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The Principles of Clinical Cytogenetics
Manufacturer: Humana Press ProductGroup: Book Binding: Hardcover Similar Items:
ASIN: 1588293009 |
Book Description
This thoroughly revised and expanded edition of a highly praised classic, The Principles of Clinical Cytogenetics, includes the many advances that have occurred in the field. Among the highlights are a full section devoted to advances in fluorescence in situ hybridization (FISH) technology, increased coverage of cancer cytogenetics-both hematopoietic neoplasms and tumor cytogenetics-and new chapters on chromosome instability and the cytogenetics of infertility. The book offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, and cytogeneticists the clear understanding they need to carry out and interpret their test results rapidly.Customer Reviews:
very happy.......2007-09-05
Must have........2005-08-02
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The Cooperative Gene: How Mendel's Demon Explains the Evolution of Complex Beings
Mark Ridley Manufacturer: Free Press ProductGroup: Book Binding: Hardcover Similar Items:
ASIN: 0743201612 |
Amazon.com
The Cooperative Gene is about sex and how sex enabled complex life to arise. Mark Ridley, a researcher and author of many works including the textbook Evolution, contends that simple life is "easy." Simple life like bacteria evolved as soon as conditions on Earth permitted. But complex life--walking, flying, swimming, squawking organisms with differentiated tissues--was a huge step forward. It took billions of years for complex life (and sex) to appear.More than anything, organisms want to pass on their genes. Sex seems to defy natural selection in its ability to convince organisms to pass on only half their genes. Natural selection will favor "selfish" genes, ones that can beat the odds and get passed on. But if this happened all the time, complex life could not exist. So how does it? Enter what Ridley describes as "Mendel's demon," a system in which genes are passed on in a random fashion. Most important, the demon prevents selfish genes from sabotaging that randomness.
Although Gene isn't a technical book, its ideas are complicated. Ridley's style is methodical, broken by the occasional dryly humorous aside. Evolutionary biologists and other assorted PhDs will no doubt be entertained. Popular-science buffs may find it slow going, but they will be rewarded by a thorough understanding of the topic.
In his last two chapters, Ridley leaps further afield, exploring the influence of technology on human evolution and speculating how future science could change us. He also examines the idea of supercomplex organisms, beings that would tower over humans in complexity to the same degree that humans tower over bacteria. It's pure speculation but compelling nonetheless, worthy of its own book. --J. B. Peck
Book Description
Why isn't all life pond-scum? Why are there multimillion-celled, long-lived monsters like us, built from tens of thousands of cooperating genes? Mark Ridley presents a new explanation of how complex large life forms like ourselves came to exist, showing that the answer to the greatest mystery of evolution for modern science is not the selfish gene; it is the cooperative gene.
In this thought-provoking book, Ridley breaks down how two major biological hurdles had to be overcome in order to allow living complexity to evolve: the proliferation of genes and gene-selfishness. Because complex life has more genes than simple life, the increase in gene numbers poses a particular problem for complex beings. The more genes, the more chance for copying error; it is far easier to make a mistake copying the Bible than it is copying an advertising slogan. To add to the difficulty, Darwin's concept of natural selection encourages genes that look out for themselves, selfish genes that could easily evolve to sabotage the development of complex life forms. By retracing the history of life on our planet -- from the initial wobbly, replicating molecules, through microbes, worms, and flies, and on to humans -- Ridley reveals how life evolved as a series of steps to manage error and to coerce genes to cooperate within each body. Like a benign and unseen hand -- what Ridley calls "Mendel's Demon" -- the combination of these strategies enacts Austrian monk Gregor Mendel's fundamental laws of inheritance. This demon offers startling new perspectives on issues from curing AIDS, the origins of sex and gender, and cloning, to the genetics of angels. Indeed, if we are ever to understand the biology of other planets, we will need more than Darwin; we will need to understand how Mendel's Demon made the cooperative gene into the fundamental element of life.
What does the cooperative gene tell us about our future? With genetic technology burgeoning around the world, we must ask whether life will evolve to be even more complex than we already are. Human beings, Ridley concludes, may be near the limit of the possible, at least for earthly genetic mechanisms. But in the future, new genetic and reproductive biosystems could allow our descendants to increase their gene numbers and therefore their complexity. This process, he speculates, could lead to the evolution of life forms far stranger and more interesting than anything humanly discovered or imagined so far.
Written with uncommon energy, force, and clarity, The Cooperative Gene is essential reading for anyone wishing to see behind the headlines of our genetic age. It is an eye-opening invitation to the biotech adventure humanity has already embarked upon.
Customer Reviews:
Law enforcement in reproduction.......2005-05-10
Fascinating Premise; Witty Writing; Vague Explanations.......2004-10-06
Excellent Book - Bizarre title change.......2003-10-03
Just to eliminate any confusion, I want to reiterate what an earlier reviewer pointed out; the title of this book is "Mendel's Demon: Gene Justice and the Complexity of Life". The American edition of the book was published with an altered title, creating the absurd impression that this book is somehow a challenge to the landmark work "The Selfish Gene" by Richard Dawkins. Some misleading reviews printed here reflect that this silliness actualy worked as a marketing tool aimed at simpletons.
Mark Ridley was an undergraduate student of Richard Dawkins at the University of Oxford and is now a colleague of his there. Throughout Dawkins' work (ie. the preface to "The Extended Phenotype") he has lauded Ridley's brilliance, and he did so again in his review of this book.
Anyone who is confused by the name change (a routine by American publishers that plays havoc with citations) ought not to be confused about the book's implied content; it is a fascinating read about fascinating topics, not a "challenge" to something that Mark Ridley hasn't the faintest desire to attack.
Better than Dawkins.......2003-04-27
The Cooperative Gene.......2002-11-18
"The Cooperative Gene" give us clues as to why and how complex life came about. It was by natural selection by ingenious solutions to copying errors and uncooperative genes. The author explains everything in a distinctive style that is very cleve... indeed.
This book is geerd to a person with a scientic background as it delves into biology, biochemistry, and cell biology, but it isn't out of reach of a well read lay person. The author's wit and intelligence comes through and he seems to get the reader involved so you're not lost. I was pleasantly intrigued by the author's historical grounding of this book and the up to date relevance. From the initial wobbly, replicating molecules, through microbes, worms and flies till we get to mankind, the author reveals how life evolved on earth.
Natural selection encouragess genes that look out for themselves, while delfish genes that could easily evolve to sabotage the development of complex life forms. Ther author painstakenly explains the difference between a selfish and a cooperative gene. As well as giving the reader his definition of Gregor Mendel's fundamental laws of inheritance... Mendel's Demon, thus, we find out about the origins of sex, gender, and cloning.
The DNA in a human being is 6600 Million letters long and codes for about thirty thousand genes. In contrast, the DNA of a bacterium is two or three million letters long and codes for two or three thousand genes. You see where coding for a human being can bring on more mistakes. Mendelian inheritance controls how genes are inherited in complex life. It combines sex, reproduction, and the probabilistic rather than certain inheritance of genes.
All in all, this book was rather captivating to me, the narrative wasn't overbearing and it easily readable, but you have to have a scientific origin to get the most out this book.
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Chromosome Abnormalities and Genetic Counseling (Oxford Monographs on Medical Genetics, No. 46)
R. J. McKinlay Gardner , and Grant R. Sutherland Manufacturer: Oxford University Press, USA ProductGroup: Book Binding: Hardcover Similar Items:
ASIN: 0195149602 |
Book Description
Chromosomal abnormalities can cause disability in children, and reproductive difficulty in parents. Many parents and couples seek genetic counseling in order to learn why they, or a relative, may have had a child with a particular collection of medical problems and/or intellectual disability. There may have been a history of multiple miscarriage, or infertility. They may want to know the outlook for a pregnancy, and what the risks might be. These and other questions concerning chromosome abnormalities are addressed in this standard text, which will be of interest to genetic counselors, medical geneticists, pediatricians and obstetricians, infertility specialists, and laboratory cytogeneticists. This third edition has been thorougly updated, and is richly illustrated and fully referenced. New chapters have been written on preimplantation diagnosis and on reproductive risks due to environmental agents. The practical applications of recent advances in molecular cytogentics are noted. The book will give counselors the information that will enable them to help concerned parents accommodate to their particular "chromosomal situation", and to determine what may be, for them, the best course of action.Customer Reviews:
Outstanding.......2002-03-08
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Catalogue of Unbalanced Chromosome Aberrations in Man
Albert Schinzel Manufacturer: Walter de Gruyter ProductGroup: Book Binding: Hardcover Similar Items:
ASIN: 3110116073 |
Book Description
This book presents a comprehensive and updated catalogue of the already large, and rapidly growing number of chromosome aberrations in man. The consistent structure of the text and references provide for rapid orientation. The catalogue is an important help for any clinician treating patients with autosomal chromosome aberrations as well as for physicians and biologists working in cytogenic laboratories and human genetic institutes.
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ISCN 2005: An International System for Human Cytogenetic Nomenclature (Cytogenetic & Genome Research)
Lisa G. Shaffer , and Niels Tommerup Manufacturer: S. Karger AG (Switzerland) ProductGroup: Book Binding: Paperback Similar Items:
ASIN: 3805580193 |
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Backdoor to Eugenics
Troy Duster Manufacturer: Routledge ProductGroup: Book Binding: Paperback Similar Items:
ASIN: 0415946743 |
Book Description
Considered a classic in the field, Troy Duster's Backdoor to Eugenics was a groundbreaking book that grappled with the social and political implications of the new genetic technologies. Completely updated and revised, this work will be welcomed back into print as we struggle to understand the pros and cons of prenatal detection of birth defects; gene therapies; growth hormones; and substitute genetic answers to problems linked with such groups as Jews, Scandinavians, Native American, Arabs, and African Americans. Duster's book has never been more timely.
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The Human Genome Project: Cracking the Genetic Code of Life
Thomas F. Lee Manufacturer: Plenum Publishing Corporation ProductGroup: Book Binding: Hardcover ASIN: 0306439654 |
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Adam's Curse: A Future without Men
Bryan Sykes Manufacturer: W. W. Norton & Company ProductGroup: Book Binding: Hardcover Similar Items:
ASIN: 0393058964 |
amazon.com
Bryan Sykes follows up The Seven Daughters of Eve with the equally challenging and well-written Adam's Curse. This time, instead of following humanity's heritage back to the first women, Sykes looks forward to a possible future without men. The seeds of the book's topics were sown when Sykes met a pre-eminent pharmaceutical company chairman who shared his surname. Using the Y chromosome, which is passed nearly unchanged from father to son, the author found that he shared a distant ancestor with the other Sykes. Along the way, he discovered that the Y chromosome was worth examining more closely. The first third of Adam's Curse is devoted to a clear and comprehensive lesson about genetics, the second narrates several fascinating stories of tracing ancestry via the Y chromosome, and the last chapters explore the history of male humanity and its future. Some readers will eagerly skim until they reach Chapter 21, where Sykes gets to the heart of the matter--why and how the Y chromosome has created a world where men overwhelmingly own the wealth and power, commit the crimes, and fight the wars. He uses the structural puniness of the Y chromosome to demonstrate that men are as unnecessary biologically as they are dominant socially. Sykes' provocative and quite personal book is likely to be unpopular among science readers who prefer their biology divorced from sociology, but his points taken in context will be difficult to refute. --Therese LittletonBook Description
The inside story of the Y chromosome's fatal flaw, as told by one of the world's leading geneticists.Male reproductive fragility has been the subject of much highly publicized recent research. Is it possible, asked the New York Times, that men face extinction? Bryan Sykes examines the validity of these shocking reports, focusing on the defining characteristic of men: the Y chromosome in their DNA. Guiding his readers through chapters like "The Blood of Vikings" and "Ribbons of Life," Sykes masterfully blends natural history with scientific fact, elucidating the biology of sexual reproduction, modern genetics, and evolutionary biology. He reveals that, while the Y chromosome makes man's existence possible, it also carries within it the seeds of his destruction. Timely and fascinating, this major work covers a wealth of controversial topics, including whether there is a genetic cause for male greed, aggression, and promiscuity; the possible existence of a male homosexual gene; and what, if anything, can be done to save men from a slow, but certain, extinction.
Customer Reviews:
So true!.......2007-06-27
Disappointing.......2007-04-20
The demise of males.......2007-01-10
Very readable...great mix of geneology, genetics, and folklore.......2006-09-14
Mada-bout the bo Y.......2006-07-17
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Genetic Testing: Care, Consent and Liability
Neil F. Sharpe , and Ronald F. Carter Manufacturer: Wiley-Liss ProductGroup: Book Binding: Hardcover ASIN: 0471649872 |
Book Description
A complete review of the issues with specific recommendations and guidelines.With over 1,000 tests commercially available, genetic testing is revolutionizing medicine. Health care professionals diagnosing and treating patients today must consider genetic factors, the risks and limitations of genetic testing, and the relevant law. Genetic Testing: Care, Consent, and Liability offers the only complete, practical treatment of the genetic, clinical, ethical, and legal issue surrounding genetic testing. The authors present protocols, policies, and models of care that are currently in use, and explain the legal framework for genetic testing and counseling that has developed in North America, particularly with regard to the law of medical malpractice.
This essential book features an international roster of esteemed contributors including, Nancy P. Callanan, Bonnie S. LeRoy, Carole H. Browner, H. Mabel Preloran, Riyana Babul-Hirji, Cheryl Shuman, M.J. Esplen, Maren T. Scheuner, Dena S. Davis, JonBeckwith, Lisa Geller, Mark A. Hall, Andrew R. MacRae, David Chitayat, Roxanne Mykitiuk, Stephanie Turnham, Mireille Lacroix, Jinger G, Hoop, Edwin H, Cook, Jr., S. H. Dinwiddie, Elliot S. Gershon, C. Anthony Rupar, Lynn Holt, Bruce R. Korf, Anne Summers, S. Annie Adams, Daniel L. Van Dyke, Rhett P. Ketterling, Erik C. Thorland, Timothy Caulfield, Lorraine Sheremeta, Richard Gold, Jon F. Merz, David Castle, Peter J. Bridge, JS Parboosingh, Patricia T. Kelly, Julianne M. O'Daniel, Allyn McConkie-Rosell, Beatrice Godard, Bartha Maria Knoppers, David Weisbrot.
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Genetic Testing Care, Consent, and Liability is a must-have resource for clinical geneticists, genetic counselors, specialists, family physicians, nurses, public health professionals, and medical students.
Download Description
This book provides the only such concise, clearly written, practical treatment of the genetic, clinical, legal, and ethical issues confronting health care professionals. It identifies protocols and policies that constitute reasonable standards of care. It also performs the invaluable job of explaining the legal framework that surrounds genetic testing to help establish policies and protocols that will protect health care professionals from allegations of malpractice. Moreover, the authors describe physician-patient relationships and how the medical genetics revolution is affecting it. It is presented in an easy-to-use format, with summaries as well as medical and legal case studies to illustrate important points.
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Deciphering Human Chromosome 16: index to the report
Sarah Jacobs Manufacturer: Information as Material ProductGroup: Book Binding: Paperback ASIN: 0955309220 |
Book Description
Deciphering Human Chromosome 16: We Report Here, and Deciphering Human Chromosome 16: Index to the Report, by Sarah Jacobs, use text in a visual way to document the ethical, economic, political and philosophical polemics associated with mapping the human genome. The Report is an ebook which contains links to over 240 websites collected in the months following publication in the journal Nature of ¿The sequence and analysis of duplication-rich human chromosome 16¿ ( Vol. 432. December 2004). Its contents change over time as the websites change, migrate or disappear. It is available as a FREE DOWNLOAD from the publisher at www.informationasmaterial.com .The Index sets fragments collected from the websites against the background of the earlier draft sequence originally published by Project Gutenberg. The solid physicality of the Index contrasts with the ever changing Report although vagaries of the printing process ensure that each copy of the Index is unique.Customer Reviews:
Strange & Delightful.......2007-03-09
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