Fundamentals of BioMEMS and Medical Microdevices (SPIE Press Monograph Vol. PM153)

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BioMEMS devices are as important to the future of medicine as microprocessors were to the computer revolution at the end of the last century. BioMEMS is a science that includes more than simply finding biomedical applications for microelectromechanical systems devices. It represents an expansion into a host of new polymer materials, microfluidic physics, surface chemistries and their modification, "soft" fabrication techniques, biocompatibility, and cost-effective solutions to biomedical problems. It brings together the creative talents of electrical, mechanical, optical, and chemical engineers, materials specialists, clinical laboratory scientists, and physicians. BioMEMS devices are the platform upon which nanomedicine will be delivered. Based on the author's course on bioMEMS at the University of Minnesota, this book is an introduction to the science and a survey of the state of the art. Topics include microfabrication of silicon, glass, and polymer devices; microfluidics and electrokinetics; sensors, actuators, and drug delivery systems; micro-total-analysis systems and lab-on-a-chip devices; detection and measuring systems; genomics, proteomics, DNA, and protein microarrays; emerging applications in medicine, research, and homeland security; and packaging, biocompatibility, and ISO 10993 testing.

Customer Reviews:

Excellent LIterature.......2007-06-01

I purchased the book in order to take the BioMEMs class offered by the University of Minnesota and taught by the author, Dr.Saliterman. As a Biomedical Engineer, it provided a very realistic and complete view on the engineering applications of the medical field in relation to medicine. Although not overly deep, the book is very well written and allows for easy understanding of the material. I found that the reaches of engineering can be extended to many devices and fields with encouraging results.

I thought that the book was a highly informative, interesting, and educational read that I will be keeping with me through medical school.

Very extensive, but hard to read........2007-05-30

I bought this book for my work in order to get a better understanding of the bio side of MEMS. Having a physics background, it is sometimes difficult to understand the needs of the medical and life sciences with respect to MEMS devices.

I think the book is very complete, it tries to incorporate all aspects of biomems, but everything is touched on only shortly. The book tries to be readable for both MEMS fabrication engineers (me) and for the medical field. But I feel that it failed in doing so by not elaborating enough. It is a steep learning curve for people with no background in chemistry.

On the other hand, it will probably find it's way on the shelve of many medical microdevice designers as it is very extensive and because of its completeness, gets 4 stars from me.

Nanotribology and Nanomechanics: An Introduction

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Nanotribology and Nanomechanics: An Introduction

Manufacturer: Springer
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Binding: Hardcover

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ASIN: 3540242678

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The recent emergence and proliferation of proximal probes, e.g. SPM and AFM, and computational techniques for simulating tip-surface interactions has enabled the systematic investigation of interfacial problems on ever smaller scales, as well as created means for modifying and manipulating nanostructures. In short, they have led to the appearance of the new, interdisciplinary fields of micro/nanotribology and micro/nanomechanics.

This volume serves as a timely, practical introduction to the principles of nanotribology and nanomechanics and applications to magnetic storage systems and MEMS/NEMS. Assuming some familiarity with macrotribilogy/mechanics, the book comprises chapters by internationally recognized experts, who integrate knowledge of the field from the mechanics and materials-science perspectives. They cover key measurement techniques, their applications, and theoretical modelling of interfaces, each beginning their contributions with macro- and progressing to microconcepts. After reviewing the fundamental experimental and theoretical aspects in the first part, Nanotribology and Nanomechanics then treats applications.

Three groups of readers are likely to find this text valuable: graduate students, research workers, and practicing engineers. It can serve as he basis for a comprehensive, one- or two-semester course in scanning probe microscopy; applied scanning probe techniques; or nanotribology/nanomechanics/nanotechnology, in departments such as mechanical engineering, materials science, and applied physics.

With a Foreword by Physics Nobel Laureate Gerd Binnig

BioMEMS and Biomedical Nanotechnology: VI: Biomedical & Biological Nanotechnology. V2: Micro/Nano Technology for Genomics and Proteomics. V3: Therapeutic ... Sensing, Processing and Analysis

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BioMEMS and Biomedical Nanotechnology: VI: Biomedical & Biological Nanotechnology. V2: Micro/Nano Technology for Genomics and Proteomics. V3: Therapeutic ... Sensing, Processing and Analysis

Manufacturer: Springer
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ASIN: 0387255613

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The frontiers of microtechnology and nanotechnology are changing the face of medicine through the efforts of researchers to build biomedical microelectromechanical systems, or bioMEMS - tiny working machines so small, they measure only a few millionths of a meter across. BIOMEMS AND BIOMEDICAL NANOTECHNOLOGY, edited by Mauro Ferrari, comprises the first comprehensive reference devoted to all aspects of research in the diagnostic and therapeutic applications of Micro-Electro-Mechanical Systems (MEMS), microfabrication, and nanotechnology. Contributions report on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices.

BioMEMS and Biomedical Nanotechnology is a comprehensive reference consisting of 4 volumes:

I: Prospectus, Biological and Biomedical Nanotechnology (Volume Editors, A. Lee and L. Lee)
II: Micro and Nano-Technologies for Genomics and Proteomics (Volume Editors, M. Ozkan and M. Heller)
III: Therapeutic Micro/Nanotechnology (T. Desai and S. Bhatia)
IV: Biomolecular Sensing, Processing and Analysis (Volume Editors, R. Bashid and S. Wereley)

This reference is devoted to research in the diagnostic and therapeutic applications of Micro-Electro-Mechanical Systems, microfabrication, and nanotechnology.

Subjects include the design, characterization, testing, modeling and clinical validation of microfabricated systems and their integration on-chip and in larger functional units. There will be specific discussions on systems for neural stimulation and recording, bioseparation technologies such as nanofilters and electrophoretic equipment, miniaturized analytic and DNA identification systems, biosensors, and microtechnologies for cell and tissue research, tissue engineering, cell transplantation and the controlled release of drugs and therapeutic proteins.

Each volume contains many figures in full color.

BioMEMS and Biomedical Nanotechnology (Biomems and Biological Nanotechnology)

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BioMEMS and Biomedical Nanotechnology (Biomems and Biological Nanotechnology)

Manufacturer: Springer
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ASIN: 0387255656

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This will be the first comprehensive treatment of the emerging area of therapeutic micro- and nanotechnology. Subjects covered include: cell-based therapeutics, regenerative medicine - merging cells with micro- and nanosystems, and integrating MEMS with cells and tissues; Drug delivery - intravascular nanoparticles for drug targeting and nonvascular delivery (implantable, oral, inhalable); molecular surface engineering for the biological interface, biomolecule patterning and cell patterning

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Bio-MEMS: Technologies and Applications

Manufacturer: CRC
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Binding: Hardcover

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Fundamentals of BioMEMS and Medical Microdevices (SPIE Press Monograph Vol. PM153)

ASIN: 0849335329

Book Description

Microelectromechanical systems (MEMS) are evolving into highly integrated technologies for a variety of application areas. Add the biological dimension to the mix and a host of new problems and issues arise that require a broad understanding of aspects from basic, materials, and medical sciences in addition to engineering. Collecting the efforts of renowned leaders in each of these fields, BioMEMS: Technologies and Applications presents the first wide-reaching survey of the design and application of MEMS technologies for use in biological and medical areas. This book considers both the unique characteristics of biological samples and the challenges of microscale engineering. Divided into three main sections, it first examines fabrication technologies using non-silicon processes, which use materials that are appropriate for medical/biological analyses. These include UV lithography, LIGA, nanoimprinting, injection molding, and hot-embossing. Attention then shifts to microfluidic components and sensing technologies for sample preparation, delivery, and analysis. The final section outlines various applications and systems at the leading edge of BioMEMS technology in a variety of areas such as genomics, drug delivery, and proteomics. Laying a cross-disciplinary foundation for further development, BioMEMS: Technologies and Applications provides engineers with an understanding of the biological challenges and biological scientists with an understanding of the engineering challenges of this burgeoning technology.

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BioMEMS (Microsystems)

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ASIN: 0387287310

Book Description

Explosive growth in the field of microsystem technology (MST) has introduced a variety of promising products in major disciplines from microelectronics to life sciences. Especially the life sciences and health care business was, and is expected to be a major market for MST products. Undoubtedly the merging of biological sciences with micro- and nanoscience will create a scientific and technological revolution in future. Microminiaturization of devices, down to the nanoscale, approaching the size of biological structures, will be a prerequisite for the future success of life sciences. Bioanalytical and therapeutic micro- and nanosystems will be mandatory for system biologists in the long run, to obtain insight into morphology, the function and the interactive processes of the living system. With such a deeper understanding new and personalized drugs could be developed leading to a revolution in life sciences. Today, microanalytical devices are used in clinical analytics or molecular biology as gene chips. In parallel, standard microbiomedical products are employed in the intensive care and surgical theatre, mainly for monitoring and implantation purposes. The gap between these two different scientific fields will be closed, however, as soon as functional micro devices can be produced, allowing a deeper view into the function of cells and whole organisms.

Here, a new discipline evolved which focuses on microsystems for living systems called "BIOMEMS". In this review at a glance the exciting field of bio-microsystems, from their beginnings to indicators of future successes are presented. It will also show that a broad penetration of micro and nano technologies into biology and medicine will be mandatory for future scientific and new product development progress in life science.

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BioMEMS

Manufacturer: Knowledge Press
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Binding: Paperback

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BioMEMS is targeted to have the fastest growth rate within the MEMS market, particularly for drug discovery and delivery, diagnostics, biotelemetry, and genomics. However, manufacturing of BioMEMS devices differs from IC manufacture because the market requires a diversity of materials, physical structures, input/output methods, products, and initally lower volumes per product. This creates an obvious need for modular, non-silicon approaches to building inexpensive disposable chemical and biological sensors and systems. Held in July 1999, this conference was one of the only MEMS conferences that focused specifically on the commercialization of BioMEMS accompanied with manufacturing strategies essential for the success of MEMS devices in the biomedical field. Conference participants benefited from specific case studies outlining commercial strategies for the successful implementation of BioMEMS into the biomedical marketplace.

BioMEMS and Biomedical Nanotechnology (Biomems and Biomedical Nanotechnology)

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BioMEMS and Biomedical Nanotechnology (Biomems and Biomedical Nanotechnology)

Manufacturer: Springer
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ASIN: 038725563X

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This volume focuses on synthetic nanodevices and the synthesis of nanomaterials and the generation of nanoscale features. The nanomaterials include polymeric microspheres and nanostructures, carbon nanotubes, silicon, silicon dioxide, and iron oxide. There is also a chapter on the characterization of critical nanostructures for bio applications such as nanochannels and nanopores. The second part involves hybrid synthetic-biomolecular nanodevices that utilize the self assembly properties of both biomolecules and synthetic materials. There is a chapter discussing the structure-function relations between biomolecular (protein) and inorganic interfaces. The third part gives the theoretical underpinning of bio nanodevices covering computation methods, informatics, and mechanics. These fundamentals are critical in designing the next generation nanodevices and also understanding the interaction between nanodevices and biological systems to enable more efficient in vitro and in vivo bio applications.

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BioMEMS and Biomedical Nanotechnology (Biomems and Biomedical Nanotechnology)

Manufacturer: Springer
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ASIN: 0387255648

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Contributions reporting on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices with applications to Genomics and Proteomics. Topics include gene expression profiling utilizing microarray technology; imaging and sensing for gene detection and use in DNA analysis; and coverage of advanced microfluidic devices and the Humane Genome Project.

BioMEMS and Biomedical Nanotechnology: Volume IV: Biomolecular Sensing, Processing and Analysis (Biomems and Biomedical Nanotechnology)

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BioMEMS and Biomedical Nanotechnology: Volume IV: Biomolecular Sensing, Processing and Analysis (Biomems and Biomedical Nanotechnology)

Manufacturer: Springer
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Binding: Hardcover

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ASIN: 0387255664

Book Description

Volume 4 of the multi-volume reference, BioMEMS and Biomedical Nanotechnology is a balanced review of key aspects of BioMEMS sensors, including (i) BioMEMS sensors and materials, (ii) means of manipulating biological entities at the microscale, and (iii) micro-fluidics and characterization. These three sections provide a succinct review of important topics within a single volume.

This volume is very well illustrated with many of the figures in color.

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