Oxidative Stress and Antioxidant Protocols (Methods in Molecular Biology)

Book Description

Donald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies demonstrated include ELISA, HPLC, infrared spectroscopy, gas chromatography-mass spectroscopy, immunoblotting, electroelution fractionation, isoelectric focusing, voltametry, and electron paramagnetic resonance imaging. Special emphasis is given to the separation of complex mixtures of plant antioxidants, soft drug design to protect from toxic oxidative metabolites, in vitro oxidation conditions, and correcting for random measurement error to improve statistical interpretation. A soon-to-be-published companion volume, Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (0-89603-851-3), contains state-of-the-art molecular and ultrastructural methods that expand the total number of protocols to 109 assays.

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A classic, but outdated in terms of information!!
The Stress of Life
A classic!

The Stress of Life
Hans Selye
Manufacturer: McGraw-Hill
ProductGroup: Book
Binding: Paperback

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The Balance Within: The Science Connecting Health and Emotions
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Stress without Distress (Signet)

ASIN: 0070562121

Book Description

no description

Customer Reviews:

A classic, but outdated in terms of information!!.......2007-02-02

I am a former physiology teaching fellow and research biochemist. In my daily life, I do stress management work with executives and others. While this book is a classic, it is NOT current and mostly of historical interest. For an easy read that is more accurate, try THE END OF STRESS AS WE KNOW IT. If you have a good biology background, then my favorite book in this genre is WHY ZEBRAS DON'T GET ULCERS by Sapolsky.

The three rating is not because it's a poorly written book, just that it is so behind the times it could be misleading. I would rate it higher for historical interest, but not for solid information on the stress response. We know much more about it now and Selye was off the mark in some important ways.

The Stress of Life.......2005-06-14

Hans Selye MD PHD,the discoverer of "biologic stress", the neuroendocrine response of the body to exposure to stressors, lays the foundation for mind-body medicine and takes the reader on a detailed journey of scientific discovery which impacts every human being. This three time Nobel Prize nominee was way ahead of his time documenting the role of stress hormones on the immune,cardiovascular,gastrointestinal,musculoskeletal and neurological systems.
Selye's interest in educating the lay public and health professionals and his committment to share behaviors and life philosophies that are protective or modulate life stressors are evident throughout. Strongly recommended for health professionals with an interest in the scientific foundation for mind-body medicine.A must read for the lay person with an interest in stress adaptation and how the brain processes life stressors.

A classic!.......2001-05-23

The "Stress of Life" is widely considered to be a classic work in the field of stress research. The "father" of the stress hypothesis, Hans Selye, lays out the concept of a "general adaptation syndrome" to stressors and presents evidence to show that the stress response of an animal or human is a short or long term attempt to maintain a state of physiological balance or "homeostasis" . A book that should be on the shelf of anyone interested in this topic.

Oxidative Stress and Signal Transduction

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A refreshing view on oxidative stress

Oxidative Stress and Signal Transduction
H.J. Forman , and Enrique Cadenas
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0412076810

Book Description

In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The work is organized in three sections. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers. The second details the connection between second messengers and the gene. The third part looks more closely at the level of the gene.

Customer Reviews:

A refreshing view on oxidative stress.......2001-02-23

Those investigators wondering what does oxidative stress mean to cell function will find in this book a new perspective. Written in an accesible language of basic cell biology, the text covers a broad range of subjects in an clear, orderly manner. Helpful in the formulation of mechanistic hypotheses for those interested in the pathophysiology and pharmacology of inflammation, cancer or aging, among others. The authors include some "big names" but are mostly mid-career and young investigators whose refreshing views, combined with the experience of the editors in the field make the book unusually exciting and meaningful.

Handbook of Antioxidants (Oxidative Stress and Disease)

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Handbook of Antioxidants (Oxidative Stress and Disease)

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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RESPeRATE Blood Pressure Lowering Device
Airborne Effervescent Health Formula, Original Orange, 10 Tablets (Pack of 3)

ASIN: 0824705475

Book Description

Offering over 4200 references, this book covers antioxidants in beverages and herbal products, nitric oxide and selenium. Including contributions from over 90 international experts, the book highlights research on food-derived antioxidants and biomarkers; vitamins E and C; coenzyme Q; carotenoids, flavoroids and other polyphenols; antioxidants in beverages and herbal products; the thiol antioxidants glutathione and lipoic acid; melatonin; selenium; and nitric oxide. The book helps readers understand the numerous conflicting health claims and the overabundance of epidemiological and clinical studies on nutrachemicals.

Nutrients and Cell Signaling (Oxidative Stress and Disease)

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Nutrients and Cell Signaling (Oxidative Stress and Disease)

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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ASIN: 0824722485

Book Description

Cell signaling is at the core of most biological processes from the simplest to the most complex. In addition to unicellular organisms possessing the essential ability to receive inputs with regard to nutrient availability and noxious stimuli, the cells in multicellular organisms require signaling from adjacent, as well as distant cells to maintain normal internal function, including growth, differentiation, and homeostasis. Conversely, the etiology of many disease processes, such as those involving immune system dysfunction and tumor development, have been traced to aberrant cell signaling. Nutrients and Cell Signaling, in presenting contributions from a wide array of experts in the field, fully delineates the role of nutrients in cell signaling. The text emphasizes broad concepts and covers all major groups of nutrients. Contributors discuss the role of carbohydrates, amino acids, lipids, vitamins, minerals, and trace elements in essential processes such as cell proliferation, immune function, and DNA repair. The editors have organized the work to provide select examples organized under these contemporary research areas: · Nuclear receptors, transcription factors, and signaling cascades · Amino acids, lipids, and glycation · Insulin release, signaling, and insulin resistance · Calcium-dependent signaling · Feeding and nutrient homeostasis Nutrients and Cell Signaling answers the need in the post-genomic era, for an authoritative resource that provides an in-depth understanding of how these complex and dynamic biomolecular networks control cell function. Those professionals and students in molecular biology, nutrition, biochemistry, as well as any branch involved with cell signaling and function will find this book to be an invaluable tool in promoting both understanding and further inquiry.

Oxidative Stress, Inflammation, and Health (Oxidative Stress and Disease)

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Oxidative Stress, Inflammation, and Health (Oxidative Stress and Disease)

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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ASIN: 0824727339

Book Description

Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-analyzing the implications of oxidative stress and inflammatory damage in the pathogenesis of human disorders such as cancer, neurodegenerative disease, and diabetes.

Yeast Stress Responses (Topics in Current Genetics)

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Yeast Stress Responses (Topics in Current Genetics)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540439269

Book Description

Every cell has developed mechanisms to respond to changes in its environment and to adapt its growth and metabolism to unfavorable conditions. The unicellular eukaryote yeast has long proven as a particularly useful model system for the analysis of cellular stress responses, and the completion of the yeast genome sequence has only added to its power
This volume comprehensively reviews both the basic features of the yeast genral stress response and the specific adapations to different stress types (nutrient depletion, osmotic and heat shock as well as salt and oxidative stress). It includes the latest findings in the field and discusses the implications for the analysis of stress response mechanisms in higher eukaryotes as well.

Measuring Stress in Humans: A Practical Guide for the Field (Cambridge Studies in Biological and Evolutionary Anthropology)

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Measuring Stress in Humans: A Practical Guide for the Field (Cambridge Studies in Biological and Evolutionary Anthropology)

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0521844797

Book Description

The purpose of this book is to present state-of-the-art non-invasive methods of measuring the biological responses to psychosocial stress in humans, in non-laboratory (field) settings. Following the pathways of Seyle's General Adaptation Syndrome, the text first describes how to assess the psychosocial stressors of everyday life and then outlines how to measure the psychological, behavioral, neurohumeral, physiological and immunological responses to them. The book concludes with practical information on assessing special populations, analyzing the often-complicated data that are collected in field stress studies and the ethical treatment of human subjects in stress studies. It is intended to be a practical guide for developing and conducting psychophysiological stress research in human biology. This book will assist students and professionals in designing field studies of stress.

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Cytokines: Stress and Immunity

Manufacturer: CRC Press
ProductGroup: Book
Binding: Hardcover

Immunology | Basic Science | Medicine | Subjects | Books

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ASIN: 0849331501

Book Description

Studies indicate that the well-known effects of stress hormones-ACTH and corticosteroids-are modulated to a large degree by various cytokines-interferons and interleukins. Cytokines: Stress and Immunity provides a comprehensive overview of contemporary knowledge of the role of cytokines in interreactions between the neuroendocrine and immune systems, and the clinical implications of these interactions. This book examines all cytokines, including interleukins, interferons, enkephalins, and endorphins. With its focus on the immune, central nervous, and endocrine systems, this book will impact a broad range of scientists, including both basic researchers and clinicians.

The Tending Instinct: How Nurturing is Essential to Who We Are and How We Live

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Solid, scientific and eminently readable
Mrs. Mankind
Redressing the balance
well-written discussion of hard-to-quantify material
Greatly informative & highly recommended!

The Tending Instinct: How Nurturing is Essential to Who We Are and How We Live
Shelley E. Taylor
Manufacturer: Times Books
ProductGroup: Book
Binding: Hardcover

Interpersonal Relations | Relationships | Health, Mind & Body | Subjects | Books

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The Tending Instinct: Women, Men, and the Biology of Relationships
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ASIN: 0805068376

Book Description

In times of crisis and upheaval, our responses to stress become especially important. We have long heard about the fight or flight response, but renowned psychologist Shelley E. Taylor points out that fight or flight may be distinctly male, and that femalesboth humans and those of other speciesare hardwired to respond to stress differently. Their tend and befriend response is not only demonstrable but, as Taylor deftly explains in this eye-opening work, a key ingredient in human social life.Accessibly and engagingly, Taylor draws on biology, evolutionary psychology, physiology, and neuroscience to show how this tending process begins virtually at the moment of conception and literally crafts the biology of offspring through genes that rely on caregiving. Taylor also examines what drives women to seek each others company, and to tend to the young and the infirmacts that greatly benefit the group but often at great cost to the individual. In the tradition of works such as Daniel Golemans Emotional Intelligence and Steven Pinkers The Language Instinct, Taylors book will forever change the way we view ourselves, and will revolutionize our understanding of the role of women and nurturing in maintaining a stable society.

Customer Reviews:

Solid, scientific and eminently readable.......2003-10-28

Shelley Taylor has pulled off a coup, integrating scientific research with anecdotes from her own life and translating academic jargon into readable prose.

Men and women differ in the way they respond to stress. After a hard day's work, men want to be alone; women spend more time with the children. And it is this tending instinct that keeps a society together and makes individuals healthier.

Men and women differ in other ways that influence social interaction, says Taylor. Men's groups are more hierarchical, women's more informational. Married men live longer than single men, and women fare better during times of major crisis, such as the dissolution of the Communist bloc.

Another key theme: Nurturing is essential to well-being. A nurturant parent can override genes that would predispose a child toward aggression, depression or other disorders.

Much of what Taylor writes will not seem radically new, but cumulatively, chapter to chapter, she builds a case for recognizing the importance of nurturing and the style of interaction known as traditionally female.

Because Taylor is a psychologist, rather than sociologist, it's not surprising that she omits suggestions and implications. Many well-educated citizens, for instance, resent payments to welfare mothers, yet Taylor's findings emphasize that paying women to nurture their children can save millions of dollars by keeping those children out of the criminal justice system.

A sociologist could point out that in fact tending seems to be punished by society. "Nurturant" occupations, such as teaching and social work, typically pay less than more aggressive occupations, such as policing. In medicine, surgeons make the most while pediatricians and psychiatrists earn the least, on average.

Taylor also ignores outliers -- the non-nurturing female and the nurturing male. -- who occupy ambivalent roles in many societies. And while she says that friends will become the most important social relationship, as we move farther from families, I find that friendship bonds often are formed based on family status. A married but childless woman says, "People my age are having babies!" and I say, "Women my age are getting visits from the grandchildren!"

As an academic, Taylor herself anticipates comments on what's working and what's missing, and she has made an exceptionally strong contribution here. I am recommending this book to readers who want to learn more about stress as well as those who are fascinated by the eternal "how men differ from women" puzzle.

Mrs. Mankind.......2003-04-09

If you have ever wondered about how the other half of the sky copes with stress! If you have ever given any thought to the science of anthropology & how it has neglected the study of how women look at life. If you have had this needling question that "What if society is a lie?" & couldn't find any answers...then this book's for you, because Shelley E. Taylor asked a seemingly innocuous question which unearthed a fascinating idea!

THE TENDING INSTINCT is a powerful, transformative read. It deals with both old & new ideas about community, society, morality & how women & men think about their lives, how we interact & cope with stress.

Very good stuff! Well written, well-researched, informative & everso interesting. You will find yourself nodding & saying "Of course! I knew that!"

Redressing the balance.......2003-02-24

When Darwin wrote that man attains "a higher eminence, in whatever he takes up, than can woman - whether requiring deep thought, reason, or imagination, or merely the use of the senses and hands," he was echoing what had been known to be true since the time of Aristotle. Taylor explains clearly and with compelling authority why this traditional viewpoint is so wide of the mark.

In marketing, the discipline in which I work it is quite evident that the world of consumer commerce revolves around the tending and befriending instincts of woman. Taylor grasps the fundamental principles of marketing better than all the commonly used textbooks. The reason is they all start out from the Darwinian perspective that humans are at core selfish. If the human brain was a computer that was programmed by evolution then the dog-eat-dog perspective might be tenable. However mammals tend their young - they have to, so the urge to nurture is a necessary part of human nature. Taylor makes it abundantly clear that it is a feminine trait - not masculine.

This book is excellent at explaining the connection between befriending and stress. It makes an excellent companion book to Hrdy's book "Mother Nature," an anthropologist, also from UCLA, that explains more details about lactation and mothering.

For woman readers this book should be inspiring and validating. For men... well it is sobering and in spots embarassing.

Thank you Shelley!

well-written discussion of hard-to-quantify material.......2002-08-12

The Tending Instinct is a seminal work, tying together ideas and data from difficult-to-quantify areas such as the psychology of stress, the emotional and physical aspects of the act of nuturing, and its [especially long-term] effects, and the biochemistry of stress response in humans and other primates, in both the long and short term. She also discusses tending in society as a whole -- that is, the nurturing infrastructure of a society, those elements of day-to-day life that make it easy to tend or be tended. Ease of access to trusted caregivers for working parents, or medical care, educational or mentorship opportunities, for example.

Taylor is synthesizing, spanning disciplines to draw together different strands of research in biochemistry, psychology, and other arenas, to propose they demonstrate human beings are overridingly a tending species, a nurturing species. Success, for h. sapiens, is existing in a strong network of support, giving and taking as one's needs require. Our most successful humans are those who inspire, those who persuade, those who build coalitions to achieve a good for the entire group.

Fascinating stuff.

Greatly informative & highly recommended!.......2002-06-04

Human beings are very complex individuals -- we are all driven to make a place in the world, yet we have different means to achieve this place...different behaviors that allow us to "survive."

In the book, "The Tending Instinct," the author shows how men and women differ in their responses in times of need. According to the author, women are born with a "nurturing" quality and tend to seek support from others during times of stress. During these times, women will also reach out to help others. This natural "tending instinct" that women have, is vital in a society and also beneficial to children who are exposed to this instinctive behavior at an early age.

MyParenTime.com highly recommends the book, "The Tending Instinct" -- this book is wonderful! It is clearly written and very interesting. Readers will find it greatly informative!

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