Average customer rating:
- A good introduction to the topic
- Well written, short explanations but nevertheless understandable
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Microarray Gene Expression Data Analysis: A Beginner's Guide
Helen Causton ,
John Quackenbush , and
Alvis Brazma
Manufacturer: Blackwell Publishing Limited
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Statistical Analysis of Gene Expression Microarray Data
ASIN: 1405106824 |
Book Description
Microarray technology is arguably the most important recent breakthrough in molecular biology. It enables researchers to obtain snapshots of gene expression for all the genes in a genome in a single experiment. Microarray experiments generate massive amounts of data that can be analysed to extract new knowledge about the underlying biological processes.This guide covers aspects of designing microarray experiments and analysing the data generated, and includes information on some of the tools that are available from non-commercial sources. Concepts and principles underpinning gene expression analysis are emphasised, and wherever possible the mathematics has been simplified. The guide is intended for use by graduates and researchers in bioinformatics and the life sciences and is also suitable for statisticians who are interested in the approaches currently used to study gene expression.
Customer Reviews:
A good introduction to the topic .......2007-05-20
Microarrays are a tool for monitoring gene expression levels for thousands of genes in parallel. This technology is very useful since patterns in the gene expression can be used for molecular characterization of phenomena that range from disease states and response to stimuli to the differences between cells of different types. The amount of information obtained from one microarray experiment can be large. These large amounts of information present new challenges in the areas of data storage, management, and analysis by biologists who are not accustomed to dealing with this much data. Also, the software used for data analysis is usually written by mathematicians and statisticians that have a minimum of training in biology.
This book addresses some of the issues faced by researchers who are beginning their first microarray experiments. It covers various aspects of designing and analyzing the results of microarray experiments. Microarrays are not limited to the study of gene expression, but this remains the most common use of the technology and therefore is the only use of arrays discussed here. This book attempts to explain the underlying concepts and principles routinely used in analysis of gene expression data. The book should be accessible by statisticians, computer scientists, and students of bioinformatics who want a grounding in the types of analysis currently used to study microarray data.
The book begins with an introductory chapter which is followed by three major chapters. As with any technology that has the capacity to detect small changes in a highly dynamic system, the underlying experimental design and the manner in which an experiment is conducted is critical for obtaining high quality data. Chapter two addresses these issues. The raw data from microarray experiments are images that must be transformed and organized into gene expression matrices. These transformations are the subject of chapter 3. Finally, in chapter 4, the common methods used for analyzing gene expression data matrices with the goal of obtaining new insights into biology are discussed. The book does a pretty good job of providing the reader with a general understanding of the nature of microarray data and how it can be analyzed. It was never meant to be a reference book or a comprehensive review, just a gentle introduction.
Well written, short explanations but nevertheless understandable.......2005-07-06
Certainly, this book can not give a complete description of microarrays, neither from an experimental nor a theoretical side. Nevertheless, the issues presented and discussed provide the reader with a solid basis for more advanced studies.
In my opinion, this book is well written, the explanations given are descriptive and understandable and its overall organization is plausible. I recommend this book as an introduction for the analysis of microarray data, because it provides a good overview of existing methods in this field. A warning: This does not mean, that all these methods are thorougly expained! It just provides an overview!! If you want to learn, e.g., clustering methods, you should consult another book (probably no other book about microarrays but a decent book dealing only with data analysis in general or clustering methods...)
Customer Reviews:
Lab Guide.......2005-10-03
The lab guide is very helpful for the lab. It was very specific and detailed.
An excellent manual for teaching decriptive embryology.......2001-05-02
I witnessed the birth of the first edition of this book when I was still a college student, and have seen its transformation to suit the needs of each new era. The book offers fundamental principles in descriptive embryology. I hoped to see more on the expperimental aspect of the subject. I also wished to see the embryology of more of the animal phyla (eg. fruit fly, zebra fish) included.
An Embryology Lab Instructor's Comments.......2000-04-28
I have used this book in my course for four years. Typically one-hundred students per year are enrolled in my course. The quality of the photomicrographs is excellent. My only criticisms of the micrographs are that 1.) The sequence of the photomicrographs would be enhanced if they were arranged in a developmental sequence. Presently, the student must flip pages constantly to view all slides relevant to a particular developmental stage. 2.) There are not enough sagittal sections of the chick embryos. 3.) 96 hour chick embryos, instead of pig embryos might be an improvement. The text is good, although not quite as thorough as the Matthews lab manual was.
Average customer rating:
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Guide to Techniques in Glycobiology (Methods in Enzymology)
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover
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ASIN: 0121821315 |
Book Description
The critically acclaimed laboratory standard,
Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Key Features
* Detailed procedures newly written for this volume
* Extensive practical information
* Rationale and strategies for carbohydrate chain analysis
Among the topics covered:
* Release of Oligosaccharides from Glycoproteins by Hydrazinolysis
* Mass Spectrometry of Carbohydrate-Containing Biopolymers
* High-resolution Polyacrylamide Gel Electrophoresis of Fluorophore-Labeled Reducing Saccharides
* Capillary Electrophoresis of Oligosaccharides
* Synthesis and Uses of Azido-Substituted Nucleoside Diphosphate Sugar Photoaffinity Analogs
* Structural Analysis of Glycosylphosphatidylinositol Anchors
* Identification of Polysialic Acids in Glycoconjugates
Book Description
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.
NEW TO THE THIRD EDITION:
* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies
* General comments to each chapter about the relevance of pathological findings to humans
* Provides essential information that can help decide the relevance of particular lesions for patients
Book Description
Now available from Waveland Press, this comprehensive, geographically balanced manual offers readers complete hands-on coverage of morphology, identification, and classification, physiological adaptations, and natural history. The book's taxonomic and geographic coverage is impressively broad as well, applying to a variety of fishes and areas: jawless, cartilaginous, and bony, fresh- and saltwater, temperate and tropical, and inshore and offshore. Helpful discussions and explanations introduce the guidebook's collection of well-designed exercises, making the connections between principles and specific inquiries easier to formulate. This approach works to help readers transform memorized facts into concepts that stimulate further explorations.
Book Description
This high-quality laboratory manual may accompany any comparative anatomy text, but especially Kardong's Vertebrates: Comparative Anatomy, Function, Evolution or Kent/Carr's Comparative Anatomy. This text carefully guides students through dissections and is richly illustrated.
Customer Reviews:
A great improvement.......2001-08-24
Having written a rather scathing review of the previous edition of this guide, I thought it only appropriate that I write a review for this fantastic rewrite. My biggest problem with the previous edition was the quality of the images. However, the majority of the poor images of the previous edition have been replaced by wonderful drawings for this latest edition. There are still a few problematic pictures (such as the alligator skull with many of the sutures not drawn), but as a whole I give the new pictures 5 stars because of the extreme detail and the ease of use. The addition of repeating the most important images at the back of the book add to this books use. And, the fact that the pages are perforated, means that a student could easily put the pictures in any order that they please. Although I had been planning on changing lab texts, I now see no point as Kardong and Zalisko, 3rd ed. is the best out there.
Excellent art, very clear directions.......2001-08-16
This 3rd edition is filled with updated art that in many respects exceeds any of its competition. Further, nearly every piece of art is printed again in the back of the laboratory manual to allow the figures to be sorted and reviewed separate from the laboratory text. This feature is especially attractive to my students.
The skeletal material is well illustrated and includes detailed descriptions of turtles and alligators not addressed in other laboratory manuals. The text is succinct and clearly organized. Especially unique and useful are the numerous short boxed essays describing particular aspects of structure-function relationships and the evolution of the specific anatomy under examination.
I strongly recommend this manual as an attractive, clearly written, and thoroughly illustrated manual to support any course in comparative vertebrate anatomy. It also makes for a wonderful reference book for vertebrate biologists.
Book Description
This lab guide gets readers up and running quickly with exercises that help them get the most out of the more than 20,000 images in
A.D.A.M.(r) Interactive Anatomy (AIA) software. Authors Lafferty and Panella are active AIA users who know what readers need to bridge the gap between systems-based anatomy books and the extensive illustration program in AIA. For college instructors and students.
Customer Reviews:
Great reference for my gross anatomy class.......2003-06-27
I liked this book because it make anatomy much easier to retain because of the detailed pictures showing the structures of the body. I'm a visual learner and found this book to be very good in showing me the difference in location between various ligaments and bones etc. I also used the following which is also available on amazon:
Spinal Anatomy Study Guide: Key Review Questions and Answers
isbn: 0971999600
This study guide helped me with the type of questions encountered in on my medical gross anatomy tests in med school. I highly recommend both books
Book Description
General Zoology Laboratory Manual is ideal for the laboratory that emphasizes the dissection and microscopic study of live and preserved specimens. Recognized for its accuracy and readability, this manual is comprehensive in its representation of the major groups of animal phyla.This new edition is suitable for a wide range of course needs and structures.
Customer Reviews:
general zoology manual.......2003-08-26
book was in good shape, fast shipping
ILLUSTRATIVE AND DESCRIPTIVE BREAKDOWN OF SPECIMENS.......2003-03-22
This "General Zoology Laboratory Manual" is a well-structured atlas, whose versatility would be appreciated by both students and teachers. The quality photos and electron micrographs used in this book are attractive.
Its primary target are Zoology undergrads; however, most High School biology tutors would find it irresistible. Its charts and pictures are accompanied by descriptive illustrations, which include accurate breakdown of the specimens' anatomy, morphology, and taxonomy.
This book assembled all those animals with characteristic features of zoological importance. Its scope ran from the lower invertebrates to the more advanced vertebrates. It is a fine practical guide.
Great Buy! Shipping was fast and transaction was smooth as.........2003-01-11
Great Buy! Shipping was fast and transaction was smooth as Mr. Clean's noggin.
General Zoology Laboratory Guide.......2000-03-28
This is an extremely informative full reference guide to high school through introductory college level biology. It's use of electron micrographs as well as color photos and diagrams makes it clear to understand,and easy to learn from. The book covers all of the most dissected specimens, and some oddballs. A must have for any teacher of biological science!
Book Description
A laboratory companion to the Forensic Science: An Introduction to Scientific and Investigative Techniques textbook, Forensic Science Laboratory Manual and Workbook, Revised Edition provides many basic, hands-on experiments that can be completed with inexpensive and accessible instrumentation, making this an ideal workbook for non-science majors. The experiments cover all the typical trace evidence tests including body fluid, soil, glass, fiber, ink, and hair. This revised edition provides numerous new experiments in odontology, anthropology, archeology, chemistry, and trace evidence. It also includes several new chemistry experiments at a slightly higher level to appeal to classes emphasizing chemistry. Experiments involving impression evidence, such as fingerprints, bite marks, footwear, and firearms, as well as forensic archeology, forensic anthropology, the use of digital and traditional photography, and basic microscopy are also featured. All of the experiments incorporate hands-on elements to facilitate the learning process. Students must apply the scientific method of reasoning, deduction, and problem solving in order to successfully complete the experiments covered and attain a solid understanding of fundamental forensic science.
Average customer rating:
- Indispensible (if you want PHS funding), but why is it for sale?
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Guide for the Care and Use of Laboratory Animals
National Research Council
Manufacturer: National Academies Press
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ASIN: 0309053773 |
Customer Reviews:
Indispensible (if you want PHS funding), but why is it for sale?.......2007-04-03
Certainly, this is a necessary text to have on hand for anyone involved in PHS-funded animal research. The fact that it is being offered for sale on Amazon confuses me, however, as copies can be obtained free of charge from the Office of Laboratory Animal Welfare (OLAW).
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