Microbial Proteomics: Functional Biology of Whole Organisms (Methods of Biochemical Analysis)

Book Description

Discover important lessons learned about whole organism biology via microbial proteomics

This text provides an exhaustive analysis and presentation of current research in the field of microbial proteomics, with an emphasis on new developments and applications and future directions in research. The editors and authors show how and why the relative simplicity of microbes has made them attractive targets for extensive experimental manipulation in a quest for both improved disease prevention and treatment and an improved understanding of whole organism functional biology. In particular, the text demonstrates how microbial proteomic analyses can aid in drug discovery, including identification of new targets, novel diagnostic markers, and lead optimization.

Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent and thorough approach throughout. Methods, technologies, and tools associated with the most promising approaches are stressed. Key topics covered include:

Microbial pathogenesis at the proteome level
Whole cell modeling
Structural proteomics and computational analysis
Biomolecular interactions
Physiological proteomics
Metabolic reconstruction using proteomics data

While presenting the practical utility of proteomics data, the text is also clear on the field's current limitations, pointing to areas where further investigation is needed.

Book Description

This book presents an authoritative and lucid summary of the major areas of glycomicrobiology. A goal of the book is to provide readable reviews of current areas of glycomicrobiology. This molecular-oriented book considers the rapidly growing field of prokaryotic glycoproteins, and the genetics of the peptide-carbohydrate links. Expert commentary on prokaryotic recognition of glycoconjugate eukaryotic receptors and eukaryotic recognition of prokaryotic receptors is a highlight of the book. The structure and function of glycoconjugates of extremophiles is presented, along with the recognition and metabolism of carbohydrate substrata by microbial enzymes. Discussion of state-of-the-art methods in the detection of microbial carbohydrates is presented. This is the first volume devoted solely to glycomicrobiology, encompassing methods, biochemistry, genetics, molecular biology, cell biology, and enzymology.

Microbial Pentose Utilization: Current Applications in Biotechnology (Progress in Industrial Microbiology)

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Microbial Pentose Utilization: Current Applications in Biotechnology (Progress in Industrial Microbiology)
Ajay Singh , and Prashant Mishra
Manufacturer: Elsevier Science & Technology
ProductGroup: Book
Binding: Hardcover

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ASIN: 0444820396

The Physiology and Biochemistry of Prokaryotes

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An Essential Microbiology Reference
A difficult but useful book
Good information, poor illustrations

The Physiology and Biochemistry of Prokaryotes
David White
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

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ASIN: 0195301684

Book Description

The third edition of The Physiology and Biochemistry of Prokaryotes covers the basic principles of prokaryotic physiology, biochemistry, and cell behavior. It presents microbial metabolism in the context of the chemical and physical problems that cells must solve in order to grow. Written in a clear, straightforward manner, the book provides a modern perspective on the diversity of microorganisms, and an updated account of the major aspects prokaryotes, such as cell structure, metabolism, developmental biology, environmental adaptation, biofilm formation, and cellular signaling pathways. It is organized according to topic rather than by organism, therefore helping students understand the general principles of physiology and metabolism. Each chapter ends with thought-provoking study questions, a summary, and an extensive list of references to outside research literature students may go to for more information and detailed explanations of material in the text. The Physiology and Biochemistry of Prokaryotes, Third Edition, is ideal for advanced undergraduate and graduate courses on microbial physiology of bacterial metabolism. It can be used in conjunction with a laboratory manual, Microbial Physiology and Biochemistry Laboratory: A Quantitative Approach, by David White and George D. Hegeman. Features of the Third Edition BLIncludes New Material on: Cell Division, Cell-Cell Signaling, Cell Development, Biofilm Formation BLContains boxed asides that cite interesting historical information about important discoveries and notable people in the field from the 19th Century to the 1960s

Customer Reviews:

An Essential Microbiology Reference.......2007-03-23

This is an excellent resource for biochemical pathways, relationships, and diagrams of prokaryotic physiology. The written material is particularly lucid, which is greatly appreciated. While the diagrams are simple and in black-and-white print, their reduced complexity lends clarity to the concepts illustrated. I highly recommend this book to anyone in the microbial sciences at the upper-undergraduate level and beyond.

A difficult but useful book.......2005-08-01

Although it seems impossible to have just one text on the huge field of microbial physiology, this book makes a very valiant effort to be just that. The details are painstakingly researched, the text is concise and clear (no fluff anywhere!), and for such a small book, the author does a masterful job of presenting a huge amount of useful information.

Of course, every book has its downfalls, the main one of this book being its lack of helpful illustrations. Sometimes you just MUST HAVE some help visually to understand something (e.g. mixed acid fermentation, sporulation) and this book often didn't offer that. (Even if there WAS a figure, it was so hard to decipher that you'd be better off with nothing at all.) Also, some huge areas of microbial physiology were completely left out like bacterial stress response.

Overall, not the best but not the worst. It's certainly not a waste of money, but you might want to have some sort of companion book to supply your diagrams and illustrations.

Good information, poor illustrations.......1998-12-22

I used this text as a supplement for my microbial physiology class and found the explantions good, if not complete. The problem I had was that the graphic representations used to show varying processes were either very lacking, or completely absent. Most good science texts use detailed illustrations and colored ink. This text provides neither and would probably serve the more experienced bacterial physiologist as a good reference.

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Proteases of Infectious Agents

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0124205100

Book Description

Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search.
Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area.

Key Features
* Includes information on the basic biology and function of proteases
* Provides global survey of current research efforts in protease inhibitors
* Illustrates how structure-based drug design targets effective and selective compounds
* Highlights important diseases that provide economically important targets
* Describes the role of proteases as important new targets for drug discovery

Bacterial Metabolism (Springer Series in Microbiology)

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Bacterial Metabolism (Springer Series in Microbiology)
Gerhard Gottschalk
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0387961534

Book Description

This concise yet comprehensive text surveys the field of bacterial metabolism in terms useful to students and researchers. Emphasis is on those metabolic reactions occurring only in bacteria. Thus, the book describes in detail the energy metabolism of the various groups of bacteria. In addition it examines pathways used by bacteria for the degradation of organic compounds, the synthesis of cellular consituents, the regulation of bacterial metabolism and the fixation of molecular nitrogen. The general arrangement of the first edition has been retained. However, it has been thoroughly revised and updated in recognition of the rapid progress of research in this field. Readers will also appreciate the increased emphasis on membrane-associated processes. From the review of the second edition: "If there is a better textbook in its fields, I'm not aware of it, and I feel the book deserves a place on the shelf of any serious student of microbiology." -ASM News

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low value

Yeast Physiology and Biotechnology
Graeme M. Walker
Manufacturer: Wiley
ProductGroup: Book
Binding: Paperback

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ASIN: 0471964468

Book Description

Yeasts are the world's premier industrial micro-organisms. In addition to their wide exploitation in the production of foods, beverages and pharmaceuticals, yeasts also play significant roles as model eukaryotic cells in furthering our knowledge in the biological and biomedical sciences. In order for modern biotechnology to fully exploit the activities of yeasts, it is essential to appreciate aspects of yeast cell physiology. In recent years, however, our knowledge of yeast physiological phenomena has lagged behind that of yeast genetics and molecular biology. Yeast Physiology and Biotechnology redresses the balance by linking key aspects of yeast physiology with yeast biotechnology. Individual chapters provide broad and timely coverage of yeast cytology, nutrition, growth and metabolism - important aspects of yeast cell physiology which are pertinent to the practical uses of yeasts in industry. The final chapter reviews traditional, modern and emerging biotechnologies in which roles of yeasts in the production of industrial commodities and their value in biomedical research are fully discussed. Relevant aspects of classical and modern yeast genetics and molecular biology are fully integrated into the appropriate chapters. This up-to-date and fully referenced book is aimed at advanced undergraduate and postgraduate bioscience students,but will also prove to be a valuable source of information for yeast researchers and technologists.

Customer Reviews:

low value.......2006-09-24

I found this introduction to yeast physiology and biotechnology to be well written and enjoyable to read. That being said, I gave it only 2 stars because the price is absolutely ridiculous. The coverage of most topics is rather superficial (not always a bad thing in an overview-type text, but inexcusable in light of the exorbitant cost of this boook), and the material is rather dated (this being a paperback edition from 1998). I'd definitely recommend that those interested in yeast research check out a copy from a library, or buy it if you can find a used copy for around 25% of the new price, but otherwise it is just not worth it.

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Prokaryotic Development

Manufacturer: ASM Press
ProductGroup: Book
Binding: Hardcover

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Microbial Physiology, 4th Edition

ASIN: 1555811582

Book Description

This book describes the exciting advances that have occurred as a result of the transition from the almost purely genetic to the molecular analysis of bacterial development.

Prokaryotic Development focuses on the experimental systems in which a great deal is known about the molecular mechanisms of development. It devotes several chapters to the organisms that have yielded the most mechanistic information, allowing more in-depth coverage of developmental processes than previously available in one place. Introductory chapters describe the biology of each group of organisms in order to place the molecular analysis in a biological and phylogenic perspective.

Book Description

Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a selection unprecedented in the history of evolution. Consequently, society is facing one of its gravest public health problems-the emergence of infectious bacteria with resistance to many, and in some cases all, available antibiotics. This book brings together a multidisciplinary group of experts to discuss this problem. It begins by examining the origins of resistance and goes on to look at how the use of antibiotics in human medicine and farming/agriculture has selected for resistant bacteria. Separate chapters describe the evolution of resistance determinants and how these are spread both within and between bacterial species. Finally, the book contains discussions on strategies for countering the threat of antibiotic resistance. A major re-thinking of our approach to the treatment of infectious diseases is proposed-that antibiotic resistance should be seen as a problem created by the disruption of normal microbial ecology. To restore efficacy to earlier antibiotics, and to maintain the success of new antibiotics that are introduced, we need to use these drugs in a way that ensures an ecological balance that favours the predominance of susceptible bacteria.

Soil Microbial Ecology: Applications in Agricultural and Environmental Management (Books in Soils, Plants, and the Environment)

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Soil Microbial Ecology: Applications in Agricultural and Environmental Management (Books in Soils, Plants, and the Environment)

Manufacturer: Marcel Dekker
ProductGroup: Book
Binding: Hardcover

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ASIN: 0824787374

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