Developmental Genetics of the Flower, Volume 44: Advances in Botanical Research

Book Description

Current major interests in this area include the study of higher level phylogenetic relationships and character evolution in the angiosperms, floral evolution, the genetic basis of key floral differences in basal angiosperms, the genetic and genomic consequences of polyploid speciation, conservation genetics of rare plant species, and phylogeography. This book provides a series of papers focused on the developmental genetics of flowering as well as the genetic control of the timing of flowering. Investigation of speciational mechanisms, evolutionary relationships, and character evolution in flowering plants and land plants utilizing a variety of experimental approaches are discussed. The chapters are excellent reviews of the current fast-moving area of research.

* Provides a brief review of genes known to regulate flower development
* Articles emphasize the classic ABC model of flower development

Gold and Silver Staining: Techniques in Molecular Morphology (Advances in Pathology, Microscopy, & Molecular Morphology)

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Gold and Silver Staining: Techniques in Molecular Morphology (Advances in Pathology, Microscopy, & Molecular Morphology)

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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ASIN: 0849313929

Book Description

Immunogold silver staining is one of the most sensitive techniques available for visualizing the location of antibodies and nucleotide probes that have been bounded to specific antigens or to nucleotide sequences. As gold and silver staining continues to advance research in molecular morphology, this book presents the information you need to know about the various staining methods, their useful applications, and the advantages and drawbacks of each process. Gold and Silver Staining: Techniques in Molecular Morphology provides a timely description of approaches, methods, protocols, and applications. The contributors cover the latest developments and a wide range of applications from highly sensitive detection of antigens to single copy detection of DNA and RNA. Some of the authors are "living legends" in the field and bring their expertise and experience to this fine collaboration. Written in one consistent style, each chapter includes a concise, but comprehensive introduction, step-by-step protocols with technical hints, and a discussion of results and critical steps. What differentiates this book from all others like it, is the status of the editors, who have worked on this technique from its inception and have produced innumerable publications on the topic. The other distinguishing feature is that all of the contributors are amongst the absolute foremost leaders from the United States and Europe. Gold and Silver Staining: Techniques in Molecular Morphology presents a complete overview and detailed descriptions of this technique that allows the visualization of molecules that have never been localized before and with hitherto unknown sensitivity. Not only does this book provide an excellent review of this field, but it also serves as a lab manual for those who want to carry out this technique in their laboratory and clinical work. Armed with this information, advances in this powerful field of research will ensue.

Duchenne Muscular Dystrophy: Advances in Therapeutics (Neurological Disease and Therapy)

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Duchenne Muscular Dystrophy: Advances in Therapeutics (Neurological Disease and Therapy)

Manufacturer: Informa Healthcare
ProductGroup: Book
Binding: Hardcover

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ASIN: 0824723252

Book Description

Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood for which there is no cure. This authoritative guide provides a clear overview of the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art information on pharmacological interventions, regenerative medicine, and gene therapy.

Intracellular Protein Degradation (Advances in Molecular and Cell Biology)

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Intracellular Protein Degradation (Advances in Molecular and Cell Biology)

Manufacturer: Elsevier Science
ProductGroup: Book
Binding: Hardcover

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ASIN: 0762303875

Book Description

This volume brings together a set of reviews that provide a summary of our current knowledge of the proteolytic machinery and of the pathways of protein breakdown of prokaryotic and eukaryotic cells. Intracellular protein degradation is much more than just a mechanism for the removal of incorrectly folded or damaged proteins. Since many short-lived proteins have important regulatory functions, proteolysis makes a significant contribution to many cellular processes including cell cycle regulation and transciptional control. In addition, limited proteolytic cleavage can provide a rapid and efficient mechanism of enzyme activation or inactivation in eukaryotic cells.

In the first chapter, Maurizi provides an introduction to intracellular protein degradation, describes the structure and functions of bacterial ATP-dependent proteases, and explores the relationship between chaperone functions and protein degradation. Many of the principles also apply to eukaryotic cells, although the proteases involved are often not the same. Interestingly, homologues of one of the bacterial proteases, Ion protease, have been found in mitochondria in yeast and mammals, and homologues of proteasomes, which are found in all eukaryotic cells (see below), have been discovered in some eubacteria.

Studies of proteolysis in yeast have contributed greatly to the elucidation of both lysosomal (vacuolar) and nonlysosomal proteolytic pathways in eukaryotic cells. Thumm and Wolf (chapter 2) describe studies that have elucidated the functions of proteasomes in nonlysosomal proteolysis and the contributions of lysosomal proteases to intracellular protein breakdown. Proteins can be selected for degradation by a variety of differen mechanisms. The ubiquitin system is one complex and highly regulated mechanism by which eukaryotic proteins are targetted for degradation by proteosomes. In chapter 3, Wilkinson reviews the components and functions of the ubiquitin system and considers some of the known substrates for this pathway which include cell cycle and transcriptional regulators.

The structure and functions of proteosomes and their regulatory components are described in the two subsequent chapters by Tanaka and Tanahashi and by Dubiel and Rechsteiner. Proteasomes were the first known example of threonine proteases. They are multisubunit complexes that, in addition to being responsible for the turnover of most short-lived nuclear and cytoplasmic protein, are also involved in antigen processing for presentation by the MHC class I pathway. Recent studies reviewed by McCracken and colleagues (chapter 6) lead to the exciting conclusion that some ER-associated proteins are degraded by cytosolic proteasomes.

Lysosomes are responsible for the degradation of long-lived proteins and for the enhanced protein degradation observed under starvation conditions. In chapter 7 Knecht and colleagues review the lysosomal proteases and describe studies of the roles of lysosomes and the mechanisms for protein uptake into lysosomes. Methods of measuring the relative contribution of different proteolytic systems (e.g., ubiquitin-proteasome pathway, calcium-dependent proteases, lysosomes) to muscle protein degradation, and the conclusions from such studies, are reviewed by Attai and Taillinder in the following chapter.

Finally, proteases play an important role in signaling apoptosis by catalyzing the limited cleavage of enzymes. Mason and Beyette review the role of the major players, caspases, which are both activated by and catalyze limite proteolysis, and also consider the involvement of other protoelytic enzymes in this pathway leading cell death.

Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology

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Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0387351345

Book Description

This book examines every major aspect of Alzheimer disease – clinical, epidemiologic, structural, chemical, genetic, molecular, and therapeutic. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins. Treatment of symptoms with therapeutic drugs is discussed, along with outcomes of and problems inherent in clinical trials for AD. The broad coverage of AD in this book benefits clinicians, educators, investigators, and health administrators.

Genetic Dissection of Complex Traits (Advances in Genetics, Volume 42) (Advances in Genetics)

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great collection of statistical genetic techniques
Collection of Genetic Epidemiological Developments

Genetic Dissection of Complex Traits (Advances in Genetics, Volume 42) (Advances in Genetics)

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0120176424

Book Description

Genetic Dissection of Complex Traits will present the full range of methodologies that are essential for understanding the basis of human genetic disorders, the origin of such diseases, and theories on how to determine one's genetic predisposition to certain genetic diseases.

Customer Reviews:

great collection of statistical genetic techniques.......2002-05-23

This book is great because it covers all the bases in statistical genetics and features authors who are some of the founders in the field. My favorite chapter is on the Newton Morton number - mine is 2 :) Definitely a good read for anyone interested in a growing field.

Collection of Genetic Epidemiological Developments.......2001-02-21

There has been a lot of development of novel statistical methods in the last decade which has resulted in a better understanding of genetic disorders. There are not many existing books on the subject. This volume is a collection of excellent papers written by some of the renowned experts in the field. The papers range from the basic concepts in genetic epidemiology to applications of some of the most recently developed statistical techniques like CART . The precautions that one needs to take while analyzing genetic data have also been addressed in details. The final chapter by Newton Morton is a treat to read and provides a great overview of the future directions in the field. Overall the book will be very helpful to all genetic epidemiologists in their research.

Recent Progress in Bioconversion of Lignocellulosics (Advances in Biochemical Engineering / Biotechnology)

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Recent Progress in Bioconversion of Lignocellulosics (Advances in Biochemical Engineering / Biotechnology)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540655778

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Recent Progress in Bioconversion of Lignocellulosics (Advances in Biochemical Engineering / Biotechnology)

Applications of Soft Computing: Recent Trends (Advances in Soft Computing)

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Applications of Soft Computing: Recent Trends (Advances in Soft Computing)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

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ASIN: 3540291237

Book Description

Soft Computing is a complex of methodologies that embraces approximate reasoning, imprecision, uncertainty and partial truth in order to mimic the remarkable human capability of making decisions in real-life, ambiguous environments. Soft Computing has therefore become popular in developing systems that encapsulate human expertise. Applications of Soft Computing: Recent Trends contains a collection of papers that were presented at the 10th Online World Conference on Soft Computing in Industrial Applications, held in September 2005. This carefully edited book provides a comprehensive overview of the recent advances in the industrial applications of soft computing and covers a wide range of application areas, including optimisation, data analysis and data mining, computer graphics and vision, prediction and diagnosis, design, intelligent control, and traffic and transportation systems. The book is aimed at researchers and professional engineers who are engaged in developing and applying intelligent systems. It is also suitable as wider reading for science and engineering postgraduate students.

Genetics and Molecular Biology of Muscle Adaptation (Advances in Sport and Exercise Science)

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Genetics and Molecular Biology of Muscle Adaptation (Advances in Sport and Exercise Science)

Manufacturer: Churchill Livingstone
ProductGroup: Book
Binding: Paperback

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ASIN: 0443100772

Book Description

This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.

Advances in Machine Learning and Cybernetics: 4th International Conference, ICMLC 2005, Guangzhou, China, August 18-21, 2005, Revised Selected Papers (Lecture Notes in Computer Science)

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Very useful resources for recent advances in machine learning researches.

Advances in Machine Learning and Cybernetics: 4th International Conference, ICMLC 2005, Guangzhou, China, August 18-21, 2005, Revised Selected Papers (Lecture Notes in Computer Science)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

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ASIN: 3540335846

Book Description

This book constitutes the thoroughly refereed post-proceedings of the 4th International Conference on Machine Learning and Cybernetics, ICMLC 2005, held in Guangzhou, China in August 2005.

The 114 revised full papers of this volume were carefully reviewed and selected from 2461 paper submissions and 1050 real conference presentations respectively during two rounds of reviewing and improvement. The papers are organized in topical sections on agents and distributed artificial intelligence, control, data mining and knowledge discovery, fuzzy information processing, learning and reasoning, machine learning applications, neural networks and statistical learning methods, pattern recognition, vision and image processing.

Customer Reviews:

Very useful resources for recent advances in machine learning researches........2007-01-11

I find this book very informative yet uptodate if you want to know what are the recent advances in machine learning field of research. The topics presented are very insteresting and easy to read and understand.

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