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- The beat goes on!
- Rhythms of the Brain
- Timing neuronal activity
- The Brain: It's All Cycles and Rhythms
- A dense but readable explanation of the temporal aspects of neural processing
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Rhythms of the Brain
Gyorgy Buzsaki
Manufacturer: Oxford University Press, USA
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Book Description
Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the co-evolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brains fundamental organizer of neuronal information. The small world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive metastable state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of cycles, Gyorgy Buzsaki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing accessible to any reader with some scientific knowledge is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.
Customer Reviews:
The beat goes on!.......2007-04-13
"Rhythms of the Brain" by Gyorgy Buzsaki is a brilliant introduction to neuronal oscillations and fundamentals of brain functions. An enjoyable and useful read for both lay reader and accustomed professional.
Rhythms of the Brain.......2007-03-22
"Rhythms of the Brain" is nothing short of phenomenal. In fact, it may be the single best book I have ever read. Gyorgy Buzsaki is clearly way ahead his his time.
Bravo!!!
Timing neuronal activity.......2007-03-09
"Rhythms of the Brain"
by Professor György Buzsáki,
(member of the Hungarian Academy of Sciences)
There are many windows to the brain, many approaches to probe its secrets. However, a very few of them allow an in depth understanding of the most complex computational mechanisms which underlie our cognitive abilities. The approach chosen by Professor György Buzsáki in his latest book "Rhythms of the Brain" is to investigate the role of timing in governing neuronal activity. The choice is exceptionally fruitful, and sheds much new light on the emergent properties and collective behaviour of neuronal ensembles. The book is presently the most authoritative introduction to this very complex field of brain research.
In brief, the book tells that "brains are foretelling devices, and their predictive powers emerge from the various rhythms they perpetually generate". This briefing sets out the two main lines of thought recurring in "cycles" instead of chapters in the book. For the one it tells that instead of simply reacting to various kinds of input, the output of our brain is able to control its input. For the other, to do this, the brain is continuously engaged in generating various kinds of rhythmic activities, which can chunk the time and group neuronal activity into meaningful collective behaviours.
The book is outstanding in several respects. Buzsáki managed to find the fragile balance in styles and detail to be digestible to the lay person and to remain exciting to the super-specialist. Thanks to the nowadays all too rare single authorship, the line of thoughts are unbroken, and the chapters are linked together by a logic arching over the entire book. Buzsáki is leading us through various disciplines with impressive accuracy. Due to the nature of the topic, beside the numerous branches of electrophysiology (from single cell intracellular activity to MEG), the tightly linked neuroanatomy, physics, mathematics and even psychology and philosophy are lined up to bring us closer to understanding the generation of rhythmic events and their functional roles in the brain. The book is a must on the shelf of not only neuroscientist, but also of all those interested in the basic laws of our brain. The thoughts the book generates will certainly oscillate and reverberate in our mind conducted by the "rhythms of the brain".
The Brain: It's All Cycles and Rhythms.......2007-02-14
György Buzsáki's new book is superb.
One of the problems for people trying to understand some of the spectacular advances in science and medicine is that much of it has become not just complex, but highly specialized, with each discipline developing its own vocabulary. Many books are written for the cognoscenti and many others by professional writers trying to explain science in lay language. There are relatively few scientists working at the cutting edges of their fields who want - or in some cases are able - to communicate their findings to a broad audience.
This book is by an internationally recognized expert, a Professor at Rutgers who is amongst the 250 most cited neuroscientists in the world. He is passionate about his topic, literate, patient and humble. In this book he takes a complex topic - the dynamic function of the brain - and unlocks not just the secrets that he and others have uncovered, but you have the chance to look over his shoulder and understand why he has reached certain conclusions, while exposing some of the human side of the scientific enterprise. It is not all objectivity and cooperation, there is also the politics, bickering and suppression and omission of data that does not fit a pet model or theory.
As the title suggests, György Buzsáki's particular field of interest is brain oscillations: it has an extraordinary capacity for generating waves that organize its activity. We have known for centuries that there are cycles that control the rhythms of our hearts, lungs, metabolism and endocrine systems. But in recent years we have begun to suspect that the brain's constantly active rhythms, including its cycles of electrical activity, are essential to its "deepest and most general functions." That in itself is fascinating, but this is a very personal book.
He begins by saying, "The short punch line of this book is that brains are foretelling devices and their predictive powers emerge from the various rhythms they perpetually generate." A little later he explains the what, when, where, how and who of his first awakening to the importance of this realization. He says that it came, "in April, 1970, during a physiology lecture given by Endre Grastyán in the beautiful town of Pécs, on the sunny slopes of the Mecsek mountains in Hungry."
As you will see, this is no ordinary account of brain function.
It is divided into thirteen "Cycles:"
Cycle 1. Introduction.
Cycle 2. Structure defines function.
Cycle 3. Diversity of cortical functions is provided by inhibition.
Cycle 4. Windows on the brain.
Cycle 5. A system of rhythms: from simple to complex dynamics.
Cycle 6. Synchronization by oscillation.
Cycle 7. The brain's default state: self-organized oscillations in rest and sleep.
Cycle 8. Perturbation of the default patterns by experience.
Cycle 9. The gamma buzz: gluing by oscillations in the waking brain.
Cycle 10. Perceptions and actions are brain state-dependent.
Cycle 11. Oscillations in the "other cortex:" navigation in real and memory space.
Cycle 12. Coupling of systems by oscillations.
Cycle 13. The tough problem.
References.
The book is well written and scholarly. But this is not the scholarship of the show off: he is a natural scholar who is interested in knowledge for its own sake and for the ways in which it can illuminate his points. He wants to be understood beyond the narrow confines of the academy. He also understands the value of cross-pollination: how findings and insights garnered in one part of science, medicine, engineering and even art, can inform his work in the brain.
The book is full of fascinating insights. He discusses the way in which the brain is a complex adaptive, self-organizing system, while the neuron-rich cerebellum is so highly efficient and so localized that it can probably not give rise to conscious experience.
Most of us will have some points of disagreement. He is, perhaps, too certain that anatomy is destiny: that we are the cycles and oscillations created by our brains. Not all of the evidence is quite so cut and dried. But it is also certain from Buzsáki's writing that he would relish the chance to debate his points.
This is a fascinating book that may in places be a little demanding for the non-scientist. But it is also a very human story that lets the readers inside the head and the laboratory of a world-class scientist and storyteller.
Highly recommended.
A dense but readable explanation of the temporal aspects of neural processing.......2006-12-01
A good popular science book will provide laypeople with an exciting perspective on the state of the art in a particular field. But this comes at a price: typically such books are written from just a single theoretical perspective, glazing over or altogether ignoring details that might be considered controversial within the academic community. To understand these deeper issues, an interested layperson would have to trudge through academic textbooks, or for the most cutting-edge topics, delve into the often impenetrable peer-reviewed literature.
And then there are the absolute best popular science books. György Buzsáki's "Rhythms of the Brain" is of this latter variety. Not only does it provide a wide-ranging and readable introduction to neural oscillators, but every crucial argument is carefully footnoted with deeper explanations, some qualifications, and suggestions for additional reading.
"Rhythms of the Brain" begins with the premise that "structure defines function," and then outlines how the architectural principles of neural networks can give rise to neural oscillations. In the process, he meticulously covers topics like the complex, small-world, scale-free connectivity of cortex without resorting to complicated equations - the concepts are carefully grounded in real-world analogies and lay terms.
Buzsáki introduces several other topics that are usually found only in mathematically sophisticated academic works on the brain: for example, how "neural noise" can actually enhance processing through stochastic resonance and the 1/f or "pink noise" signature of EEG, mechanisms of "phase precession" and "phase reset" within nested oscillations, and the difference between relaxation and harmonic oscillators.
It is perhaps not surprising that Buzsáki is the author of such a book - holding both an MD and a Neuroscience PhD, Buzsáki's has published over 185 peer-reviewed publications, 10 book chapters, and 2 edited volumes spanning the last 35 years. His lab at Rutgers consists of a veritable army of researchers, including 8 post-docs and 4 grad students.
After reading "Rhythms of the Brain," it's easy to understand why there's so much demand for working in this laboratory. There's potentially an entirely new field of neuroscience lurking in here: Buzsáki discusses distinct oscillations with frequencies spanning 4 orders of magnitude, from the ultra-slow ("slow 4": .02 Hz) to the ultra-fast ("high gamma": 600 Hz) and everything in between.
Although this book is probably not suitable for entry-level laypeople (a good popular science introduction to the brain and its rhythms is "I of the Vortex"), it is virtually guaranteed to please everyone with some previous neuroscience experience, literary or empirical. Beware also that "Rhythms of the Brain" is quite dense (with the copious footnotes constituting almost an entire second volume!) and is therefore more likely to be enjoyed with caffeine than as a relaxing bedside book.
Some may criticize "Rhythms of the Brain" for failing to offer a comprehensive "big picture" summary of how each of these oscillations contribute to cognition (although hints are there, to be sure). For me, this is actually a strength of the book; half-informed conjecture and hasty extrapolation ruins far too many popular "science" books on the brain, and they become prematurely outdated. Besides, such speculation is far more fun to do as a reader - and for this Buzsáki has provided fertile ground.
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Introducing Biological Rhythms: A Primer on the Temporal Organization of Life, with Implications for Health, Society, Reproduction, and the Natural Environment
Willard L. Koukkari , and
Robert B. Sothern
Manufacturer: Springer
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ASIN: 1402036914 |
Book Description
Introducing Biological Rhythms is a primer that serves to introduce individuals to the area of biological rhythms. It describes the major characteristics and discusses the implications and applications of these rhythms, while citing scientific results and references. Also, the primer includes essays that provide in-depth historic and other background information for those interested in more specific topics or concepts.
It covers a basic cross-section of the field of chronobiology clearly enough so that it can be understood by a novice, or an undergraduate student, but that it would also be sufficiently technical and detailed for the scientist.
Customer Reviews:
Feedback from others the authors have received.......2006-08-17
As a co-author of the book "Introducing Biological Rhythms," I would like to share with potential readers some of the comments that we have received from others who have already received a copy. I hope this may help others who might be interested in some of the topics in our book. Thanks.
"I started immediately to read [the book] and also brought it with me on the train, in the plane and any place where I could sit and read. It is well written... To me it is the only book today that covers the whole field of Chronobiology, and you find everything there. It is a very useful reference that I will recommend to anybody that might be interested in the field. I will also get the institute to buy extra copies... I am really impressed by your work." Ole D. Laerum, PhD, Director, Stem Cell Research Group, The Gade Institute, Department of Pathology, Haukeland University Hospital, Bergen, Norway.
"It represents an encyclopedic coverage viewed from Minnesota...; the infradian cover is particularly interesting." Hugh H. Simpson, MD, Division of Pathology, Royal Infirmary, Glasgow, Scotland.
"The book looks beautiful... Congratulations for this great amount of work, with an approach that is different from the one now `in vogue' in our field!" Francis Lévi, MD, Directeur, Cancer Chronotherapeutics, Hôpital Paul Brousse et Université Paris XI, Villejuif, France.
"I am impressed by the number of pages that you have written. It is not surprising that this work demanded several years. I will now read it with a great deal of interest." Bernard Millet, PhD, Botany Laboratory, Besancon University, Besancon, France.
"I just received your book, congratulations. I already have my students using it. It is great. What a marvelous accomplishment." Jayna L. Ditty, PhD, Dept of Biology, St. Thomas University, St. Paul, MN.
"Your book is magnificent. I very much respect your work and opinions about rhythms. I hope to give the book some serious reading in the near future. Will pass your book info on to other scientists." Helen V. Ratajczak, PhD, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT.
"I'd like to share, now as a reader, my very good impression of your book. I like it very much. It's written in a way I appreciate in books - with clear aims and clear messages. The Take-Home Message is a great thing. I like the style - friendly and simple (even when you're presenting complicated things!), with nice humor." Oleg Tsinkalovsky, MD, Centre of International Health, University of Bergen, Bergen, Norway.
"You have my sincere gratitude for undertaking the Herculean and useful task, for your scholarship in doing it, and for the broad scope of the book on which I congratulate you, and I trust that in reading it I can learn much more about the field and about the two authors." Franz Halberg, MD, Halberg Chronobiology Center, University of Minnesota, Mpls, MN.
Average customer rating:
- Be Your Own Chronobiologist
- Invaluable, just when a friend needed it
- Not enough as I wanted.
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- Keeping In Time With Your Body
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The Body Clock Guide to Better Health: How to Use Your Body's Natural Clock to Fight Illness and Achieve Maximum Health
Michael Smolensky ,
Lynne Lamberg , and
Michael, Ph.D. Smolensky
Manufacturer: Owl Books
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ASIN: 0805056629 |
Amazon.com
We've all used the terms night owl and early riser; all felt the intense hunger pangs of midday and the subsequent ebb of energy after lunch; and all know what time of day we prefer to exercise or have sex. As explained in The Body Clock Guide to Better Health, these are normal cycles controlled by a sort of biological timepiece (housed in the brain's hypothalamus) that regulates everything from sleeping and eating patterns to heart rate, body temperature, and hormone production. These rhythms are vital to everyday functioning, yet, the authors claim, they're mostly overlooked when doctors prescribe treatment. This oversight, they suggest, diminishes the effectiveness of medical care; the potential for recovery and better health is enhanced when the timing of medication and other treatment is aligned with certain internal rhythms.
The Body Clock is an exhaustive guide to the merits of chronotherapy, which synchronizes healthcare with the patient's internal clock. This can be as simple as taking pain relievers at the time of day the body will best benefit from the medication, such as several hours before the patient's pain threshold will be at its lowest. (For most people, this is in the early morning; for this reason you're probably better off scheduling dental work in the late afternoon if possible.) Chronotherapy also has been shown to be effective for people managing chronic health problems such as asthma, fibromyalgia, and arthritis.
The authors, Michael Smolensky, who is director of the Memorial-Hermann Chronobiology Center and a professor at the University of Texas-Houston's School of Public Health, and Lynne Lamberg, a health writer, explain how monitoring one's clock by keeping a "chronorecord"--a personal chart that maps variations in mood, alertness, sleep cycle, eating habits, and symptoms of pain--can empower us in achieving long-term vitality. Chapter by chapter, they show how timing is everything, whether applied to weight loss, sleep, sex, exercise, or recovery from illness. In the section "Sickness and Health from A to (Nearly) Z," they address issues ranging from depression and hay fever to heartburn and skin disorders, giving practical advice on how to integrate awareness of the body clock and conventional treatment methods. For example, application of topical treatments such as moisturizers and hydrocortisone creams may be more beneficial in the afternoon than the morning because body temperature is higher and the skin more porous. Chronobiology may also explain the seasonality of illnesses: multiple sclerosis tends to worsen in late spring and summer; testicular cancer is diagnosed more in winter; and postmenopausal women detect their own breast cancers most frequently in the fall, probably due to "annual cycles in ... hormone activity or seasonal changes in melatonin secretion."
Aside from the insight we gain into our body's rhythms, perhaps The Body Clock's most valuable contribution is its advocacy of a more holistic understanding of bodily cycles and our capacity for healing. While not a replacement for conventional medical care, chronotherapy may at least give a helping hand in the process of recovery and health maintenance, adding a more personal dimension to the ordinary routines of conventional medical care. The Body Clock is an engaging resource for those who take, or want to take, an active role in wellness. --Rebecca Wright
Book Description
A medical breakthrough explained by the leading authority on the connection between health and your body clock.Chronotherapy -- adjusting the care of the body to coincide with the body's natural clock -- is poised to be the next major revolution in medical science. An understanding and awareness of these rhythms will enable us to maximize the effects not only of medications and other treatments but also of diets, exercise programs, and other daily routines. The Body Clock Guide to Better Health combines a detailed discussion of major issues, such as sleep, exercise, and nutrition, with a comprehensive A-to-Z reference to specific disorders. Among the health concerns it addresses are AIDS, arthritis, asthma, ADD, cancer, depression, diabetes, digestive problems, allergies, heart disease, chronic pain, sexual dysfunction, and complications from pregnancy. General chapters explore the big picture -- including monthly cycles and life cycles -- and provide invaluable advice on foods and dietary supplements, fitness, better sex, jet lag, and more. The Body Clock Guide to Better Health offers readers the dual benefits of improving the treatment of specific conditions while boosting their overall health and wellness.
Customer Reviews:
Be Your Own Chronobiologist.......2005-11-23
This extremely important book is written for the general public and inspires us to become amateur chronobiologists ourselves because we are the ones who can make many more discoveries that will benefit our health. Having become curious as to why I get really strong cravings to eat junk food only in the evening, three years ago I found that bright light in the afternoon either from the daylight or from a light box, stops my food cravings. In the chapter "Time to Eat" the book says that people with the eating disorder bulimia often consume vast quantities of food in the evening. Perhaps I have found one of the reasons, and one of the cures for the so-called obesity epidemic. This could put Overeaters Anonymous out of business. The chapter "How Your Body Clock Works" says that we need three to eight hours of daily daylight in order to synchronize our body clock. Yikes! Who gets this amount ? Perhaps all the beautiful buildings we are building that keep us indoors are damaging our health in many unknown ways. I hope that schoolchildren are learning about this important topic in science class. But I guess being in school all day isn't helping.
Invaluable, just when a friend needed it.......2004-12-12
I had bought this book but hadn't really paid attention to it -- bought it for one thing, found that, then put it on my medical reference shelf. Then a friend started having a sleep disorder that was really ruining his life. He went to one sleep specialist who put him on a medication for which even the pharmacist thought she had prescribed an awfully large dosage, and it didn't help that much, so she sent him to another specialist, who recommended a light box in the morning. He bought the thing, but thought it was kind of nutty, and after I set it up for him I came home and looked in this book and found a whole section explaining various forms of sleep disorder, with three or four possible explanations for his, including why and how the light box might work. I also realized that he and his wife do not close the blinds in their bedroom, which is a factor I don't think they ever considered. So I am buying a second copy of the book for them. What doctors fail to do, so often, is explain why they are doing something -- or explain it skimpily, or you can't take in what they do say because you are hearing new information that sounds weird...whatever, I know the explanations in this book are going to be useful to my friend, and now I will look through the other sections to see what else is there. Thank you, Smolensky and Lamberg.
Not enough as I wanted........2004-10-31
Good information and tips, but most of them already known before. However, it`s ok if you know absolutely anything about body cycles
Disappointing.......2001-08-06
I bought this book on the strength of its good reviews but was disappointed. It did not deliver the depth of information which I expected. A much better coverage of related issues can be found in Dennet's "Promise of sleep".
Keeping In Time With Your Body.......2001-07-11
Did you know that the majority of people don't know how to tell time? Body time, that is, and "everybody" includes a lot of doctors and other health professionals. The Body Clock Guide to Better Health explains about your body's personal body rhythms and a new field of medicine called chronomedicine.
Body time matters in almost every phase of your life. It's especially essential in keeping you healthy. The time of day you take your medication can affect how well the medicine works and whether there will be side affects. The time of day you take diagnostic tests - blood tests, urine tests, even your blood pressure, can make a change in what results the test shows.
The study of the body and time has been going on for many years. Way back in 1735, an astronomer in Paris noticed the way a plant responded to morning and night. He wondered if it was the light that caused the responses, and to find out, locked the plant in a dark closet. Much to his surprise, despite the lack of sunlight, the plant still raised its leaves in the morning and lowered them at night. It took many more years to discover just how the system worked.
Are you a lark, an owl or a hummingbird? Smolensky and Lamberg explain just what these three types of body rhythms are and how they affect you and your lifestyle. They suggest you should study your own body rhythms to find out if you are a day or a night person or somewhere in-between.
Your body clock affects not only your physical reactions, but your mental ability as well, and can explain a lot of mood swings. The Body Clock Guide talks about the different stages of sleep from very light sleep to the deep, healing sleep everyone needs. What is REM sleep? You'll find the answer in this book, and also discover just why you need to get adequate sleep and what sleep deprivation does to you.
Chapter Eight takes you through the years from babyhood to the teens and explains the differences for each age group. Babies are already cyclic in their sleep patterns, and tend to sleep more at night than during the day starting on their second day of life. Do you know why teens are like zombies in the morning? The Body Guide explains the changes in sleep needs for these difficult years.
Your body clock and rhythmic cycles affect so many things. Exercise and sports, for instance. Should you exercise in the morning or later in the day? Does your menstrual cycle make a difference? When you exercise and the type of exercise can make a difference on how well or how poorly you sleep. How our bodies handle food is also governed by when we eat, and the food we eat has an influence, again, on how well we sleep.
The Body Guide also covers sexuality and the best times to engage in sex. Want to get pregnant? Keep track of your body's rhythms. Most people know about the hormonal changes in a woman's body as she moves into menopause. But were you aware that men approaching mid-life also experience hormone changes? The Body Guide goes on to discuss how to cope with jet lag and about the use of chronobiology in the workplace to improve working conditions and accommodate those with a different body rhythm or those who have to work shift work.
Healing depends on your own body rhythm. The Body Guide gives a list of illnesses from A (AIDS) to U (Urinary disorders,) and explains when their symptoms are most and least troublesome over the day and when it's best to treat them.
And what is to come? The authors believe that in the twenty-first century, there will be better health through the use of chronotherapy. Computers will facilitate the way we keep track of our body rhythms and the times our bodies exhibit unusual patterns. Further research and education will foster a deeper understanding of chronobiology.
Throughout the book you'll find charts, illustrations and self tests to help you understand chronobiology and your own body rhythms. Also included are diaries to help you keep tabs on your health. For those who want to learn more, the authors have included an extensive list of resources.... I would recommend The Body Guide to Better Health to anyone who wants to learn what makes his or her body tick.
Average customer rating:
- A must-read
- A must-read
- The Protein Tick and the RNA Tock
- Body Clocks vs. Mechanical Clocks
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Rhythms of Life: The Biological Clocks that Control the Daily Lives of Every Living Thing
Russell G. Foster , and
Leon Kreitzman
Manufacturer: Yale University Press
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ASIN: 0300109695 |
Book Description
Why can’t teenagers get out of bed in the morning? How do bees tell the time? Why do some plants open and close their flowers at the same time each day? Why do so many people suffer the misery of jet lag? In this fascinating book, Russell Foster and Leon Kreitzman explain the significance of the biological clock, showing how it has played an essential role in evolution and why it continues to play a vitally important role in all living organisms.
The authors tell us that biological clocks are embedded in our genes and reset at sunrise and sunset each day to link astronomical time with an organism’s internal time. They discuss how scientists are working out the clockwork mechanisms and what governs them, and they describe how organisms measure different intervals of time, how they are adapted to various cycles, and how light coordinates the time within to the external world. They review problems that can be caused by malfunctioning biological clocks—including jet lag, seasonal affective disorder, and depression. And they warn that although new drugs are being promoted to allow us to stay awake for longer periods, a 24/7 lifestyle can have a harmful impact on our health, both as individuals and as a society.
Customer Reviews:
A must-read.......2005-06-18
A comprehensive and fascinating book about the last few decades of chronobiological research. Are you an "early bird" or a "night owl"? Do you want to know how to deal with jet lag and winter blues? Are you interested in biological rhythms from a scientific or professional point of view? The you have to read this book immediately. It contains nearly everything you always wanted to know about rhythms but were afraid to ask. It's a must-read for medical professionals, psychologists, teachers, trainers and consultants of all kind.
A must-read.......2005-06-18
A comprehensive and fascinating book about the last few decades of chronobiological research. Are you a "early bird" or a "night owl"? Do you want to know how to deal with jet lag and winter blues? Are you interested in biological rhythms from a scientific or professional point of view? The you have to read this book immediately. It contains nearly everything you always wanted to know about rhythms but were afraid to ask. It's a must-read for medical professionals, psychologists, teachers, trainers and consultants of all kind.
The Protein Tick and the RNA Tock.......2005-01-11
What do the disasters of the _Titanic_, the _Exxon Valdez_, Chernobyl, Three Mile Island, and the Union Carbide plant explosion in Bhopal all have in common? They involved human error, and they all happened when the humans ought, by biological fiat, to have been sleeping. We are ruled by our clocks now, but even in the unnatural world we have made for ourselves, we cannot get away from the natural clocks that our cells expect us to follow. Like almost all living things in the planet, from plants to bacteria to birds, we have "a biological clock that was first set ticking more than three billion years ago." In _Rhythms of Life: The Biological Clocks that Control the Daily Lives of Every Living Thing_ (Yale University Press), Russell G. Foster, a professor of molecular neuroscience, and Leon Kreitzman, a writer and broadcaster, have examined the investigations of a relatively new science, chronobiology, to show just how much sway natural time has over us and other organisms. It isn't just a tale of sleepy people in control making bad judgments, although cognition and prudence do have their daily cycles. We tend to have babies (natural birthing) in the early mornings, and heart attacks in the later morning, and lovemaking around 10 p.m. Physical coordination, liver metabolism, body temperature, heart rate, kidney function, and much more all are paying attention to the biological clock, and when we jump time zones or do shift work, we do so at our peril.
Many of these cycles are specifically examined here, along with the historical hunt for the biological roots of the rhythmicity. A couple of the chapters dealing with the dance of molecules will be daunting for those uninitiated into the basics of cellular biology, but they do well to show the intricacies of the molecular mechanisms and the depth of work that has been done in this field. There are not just daily rhythms, but annual ones. Migratory birds the whole world over know when to start their travels north or south; they do so not by counting the days or paying attention to when the weather changes, but by regulation from the annual changes of lengths of day and night. Plants cannot migrate, but they are regulated by day length, too; wheat flowers, for instance, when the days get long enough, and barley does so when the days start to shorten. The almost universal attention that species pay to daily or annual changes indicates that success comes from being able to predict when winter, or summer, or nightfall, or other events, are coming, and from timing leaf drop, coitus, or swimming upstream to meet the optimum times and conditions. Evolution has selected the species that are best able to predict the future.
In the famous experiments where humans lived in caves or other light-deprived environments, with no capacity to tell time, they eventually locked into their own cycles of a little more than 24 hours. Like most creatures, we have an internal daily rhythm which is not exact, but only approximate; the day night cycle (or for us, such cues as an alarm clock) "entrain" the internal cycle and keep it synchronous with the rest of the creatures on Earth. There are mutant rats and flies who have cycles that are too long or too short, and researchers have productively transplanted brain parts to find out where the actual clocks are. Chronobiologists (a term that even some chronobiologists think of as pompous) are not just doing ivory tower investigations. There are many practical implications of this sort of work. Breast cancers, for example, have an annual pattern of increased and decreased growths, and so searching for the cancer would be more productive at certain times of the year. Chemotherapy for cancers involves poisoning the cancer cells with drugs that are also poisons for regular cells, but cancer cells, with their out-of-control growth, lose their rhythm of growth and division that normal cells retain. Thus it is possible that administering anti-cancer drugs at the time of day when they will interfere the least with the normal cells could reduce the worrisome side effects of the drugs. Asthma is most prevalent at night; medicine for it would be best taken in higher doses at nighttime, rather than every eight hours. The timing of doses in some cases may be as important as what the doses contain. The authors have given a detailed but readable introduction into a new science that will have increasing importance for human health as more is learned.
Body Clocks vs. Mechanical Clocks.......2004-09-23
For the first few million years of life, time was measured by sunrise and sunset. Now we have switched to clocks. But the biological clocks that are within all of us don't know how to read clocks. Breakfast, lunch and dinner occur at standard times. Tooth pain is lowest after lunch; proof reading and sprint swimming are best performed in the evening; labour pains more often begin at night and most natural births occur in the early hours; sudden cardiac death is more likely in the morning (from Chapter 1).
The study of biological clocks has gone on for a long time, but as a science is a fairly recent development. Research in just the last few years has dramatically altered the way scientists view them. This book is a snapshot of the way the science appears right now. The pair who wrote the book are a leading researcher in the field and a professional science writer. This is a good combination that gives good enjoyable writing combined with accurate reporting.
Average customer rating:
- Great book on non-linear dynamics of metabolic pathways
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Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour
Albert Goldbeter
Manufacturer: Cambridge University Press
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An Introduction to Systems Biology: Design Principles of Biological Circuits (Chapman & Hall/Crc Mathematical and Computational Biology Series)
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Nonlinear Dynamics and Chaos: With Applications to Physics, Biology, Chemistry and Engineering
ASIN: 0521599466 |
Book Description
This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.
Customer Reviews:
Great book on non-linear dynamics of metabolic pathways.......2006-03-10
Albert Goldbeter wrote in the 70s the first articles with models on the oscillations that arise from positive feed-back regulation on metabolic pathways and since then much work has been done by him and other groups on the non-linear behavior of these systems.
This book has great chapters such as the one decribing the transitions the glycolytic pathway can suffer when some biological parameters are modified, varying from a steady-state metabolic flux to an oscillatory, complex or even chaotic one.
The math is quite advanced and in order to fully understand the consequences withdrawn from the models the reader will need a good knowledge of calculus more specifically of systems of non-linear differential equations.
In order to get full advantage of this book I would recommend fetching his early articles in pubmed with the numerical parameters for the equations as well as implementing these models in Matlab or Mathematica.
Average customer rating:
- It probably works if you try it, but...
- $1.00 used - Worth the Time to Read It !
- great great book
- At last, a palatable diet that's easy to stick to!
- The Best Diet Book Ever!
|
The Circadian Prescription: Get in Step with Your Body's Natural Rhythms
Sidney MacDonald Baker , and
Karen Baar
Manufacturer: Putnam Adult
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Genetic Nutritioneering
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ASIN: 0399145966
Release Date: 2000-04-20 |
Amazon.com
Each of us has a circadian rhythm--daily cyclical changes in chemistry and behavior--that are measured by shifts in body temperature, blood pressure, heartbeat, breathing, and body chemistries. When our circadian rhythms are disrupted by poor lifestyle choices, optimum health is sacrificed. The Circadian Prescription: Get in Step with Your Body's Natural Rhythms to Maximize Energy, Vitality, and Longevity by alternative health expert Sidney Baker, M.D., with Karen Baar, M.P.H., provides a simple 10-step plan to right your rhythms.
This thought-provoking, clearly written book based on experimental science and the experiences of Dr. Baker's patients will challenge many commonly held nutritional beliefs. At the center of the prescription is the Circadian Diet, a flexible eating plan designed to give the body the fuel it needs when it needs it (according to Baker, that means protein during the day and carbohydrates at night). The plan also includes breathing and meditation techniques, rhythmic exercise, and tips to improve sleep habits, beat jet lag, and overcome odd work shifts. Separate chapters are also devoted to weight loss, the role of intestinal flora and phytonutrients, and the specific needs of women, men, and children. --Ellen Albertston
Book Description
The first book to provide an easy-to-follow dietary and lifestyle program to enhance the body's natural rhythms for optimum health.
All living things are subject to natural patterns of eating, sleeping, and other vital functions. Disrupting these daily, or circadian, rhythms through poor diet or lifestyle results in a wide range of conditions, from fatigue and emotional imbalance to intensified symptoms of insulin resistance and other chronic health problems.
The Circadian Prescription offers a breakthrough, scientifically sound 10-point program to help anyone:
sleep better and feel energized all day long;
alleviate symptoms of menopause, jet lag, and ADD;
treat and prevent infertility, prostate disease, and Syndrome X;
enhance mental acuity and emotional balance; and
achieve and maintain ideal weight.
At the core of the program is a powerful eating plan that gives the body what it needs when it needs it by simply increasing protein intake in the early part of the day and moving most carbohydrates to the evening. The straightforward, nonrestrictive diet incorporates specific foods that provide vital information to the body to reduce risk factors for chronic disease. Plus, practical techniques--exercise, breathing, and meditation--help bring the entire body into balance.
Customer Reviews:
It probably works if you try it, but..........2007-08-24
Too complex for me! Especially with three kids a job a husband pets and god knows what else. I do believe in his theory, though, and I'm certain it works. Maybe when my last baby goes to college I'll give it a try.
$1.00 used - Worth the Time to Read It !.......2005-09-09
I had dimly begun to suspect the reasoning myself - advertising bombards us with "Carbohydrates Are For Energy", but they always seem to put me to sleep during the day when I need to think clearly. Peeking inside, Dr. Baker says effectively 'duh you idiot that's right save the carbos for dinner'. Liking this reinforcement of personal intuition, I immediately bought the book !
"Protein-in-day, carbs-at-night" is of course not patentable, but it seems to work, and the details are worth $1.00, plus which it is fairly information-dense, not one of those padded tomes.
great great book.......2002-11-26
This guy makes a lot of sense. check it out.
At last, a palatable diet that's easy to stick to!.......2002-02-12
Wish I'd read this book before moving to Seattle, one of the darkest cities in North America, and living there for 17 years! Each year when the rains started and lasted for months and months, I'd typically gain 15-25 pounds. If the sun came out long enough in the summer, I'd sometimes lose most of my winter weight. When the sun was out, diet was easy. When the sun was not shining, I could not stop eating. I arrived in Seattle weighing a petite 103 pounds and wearing a size 5 and left Seattle barely able to sqeeze into a size 14-16.
Now I've moved to a sunny state and have quite a few pounds to lose. The high-carb, low-fat diets left me hungry all the time. The low-carb diets left me feeling depressed. The carbohydrate addicts diet was too restrictive, no carbs except at one meal per day. On the Circadian diet, I don't feel an overwhelming urge to eat all the time. In fact, last night, after a very small dinner, I felt more full than I usually do after a very large meal. The diet is palatable, too. While protein is emphasized during the day, a little bit of carbohydrate is allowed, and it makes the meals a lot more appetizing. So, I can have a few chunks of pineapple with my cup of cottage cheese when I'm in a hurry and have to prepare a quickie lunch. Or I can have a piece of high fiber bread with my omlette at breakfast. And I can have some protein with my carbs at dinner. Eating out is easy. After failing at high-carb, low-carb, Weight Watchers, Diet Center, et cetera, I finally have a satisfying way to eat and am losing weight. In fact, I easily lost three pounds my first week on the diet. I learned a lot of useful information from other diet books but could not stick to the diets. After reading The Circadian Prescription, I find losing weight is pretty easy! With the other suggestions in the book, I overall feel much better than I have in years!
The Best Diet Book Ever!.......2001-12-25
This book is a literally a lifesaver! For years I have struggled to stay awake, alert and function with ADD, Candida and other health problems....the diet that is recommeneded allows me to feel alert when I need to be alert and relaxed when necessary by eating differently at different times of the day,and not be famished and weak with hunger in-between. This concept is radically different from anything else that I've ever read..but it works! I've always assumed that somehow each individual was so unique that we needed different diets ....this is a diet that seems to work for everybody, regardless or age, sex, health or lack of it...The breakfast shake in particular is a gem..and can even be used for lunch if needed..it gives me lots of energy and carries me to lunch without the usual mid-morning hunger that usually plagues me.
I have even introduced a friend to the concept and she was blown away too. Thank you Dr. MacDonald, from the bottom of my heart.
Average customer rating:
- Great Common Sense "Diet" Book
- Great Book - a novel approach that gets results
- Conflicts with much in recent understanding
- Can Change Your Life
- Great book!
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The 3-Season Diet: Eat the Way Nature Intended: Lose Weight, Beat Food Cravings, and Get Fit
John Douillard
Manufacturer: Three Rivers Press
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Tanita BC533 Glass Innerscan Body Composition Monitor
ASIN: 0609805436
Release Date: 2001-03-13 |
Book Description
* Do you drink coffee in the morning to get your day started?
* Do you work through lunch?
* Do you crave sweets or a nap in the afternoon?
* Have you tried losing weight in the past three years and given up?
* Do you tend to have bouts of worry, anxiety, and depression?
* Do you have difficulty remembering things?
If you do, this book will help you restore balance to your daily life. By following its simple instructions for eating foods appropriate to each season, adjusting your diet to your body type, eating at the optimal time of the day, and exercising without triggering a survival response, you will not only lose excess pounds and maintain your ideal weight, you will generate energy and power in your life.
Derived from a 5,000-year-old traditional medical system, the 3-season diet does what no other diet will: work along with the body's natural response to the changing seasons, feeding it what it craves and can best utilize at all times. In spring, for instance, we want salads, berries, and leafy greens, a naturally low-fat diet. And in winter, we yearn for hearty soups, nuts, warm grains, and high-fat and protein-rich foods such as fish and meat. Following the foods that nature provides seasonally creates the best diet for balancing weight, mood, and energy for anyone living anywhere on earth.
Customer Reviews:
Great Common Sense "Diet" Book.......2007-06-27
Excellent book with a lot of common sense lifestyle suggestions (that are easy to follow) and a big picture overview of why his guidelines are so important to your overall health and well-being. Would recommend it to anyone!
Great Book - a novel approach that gets results.......2007-05-14
The teachings of ayurveda have been around for 5,000 years and in this book Douillard brilliantly some of these lessons to light for those of us in the Western world. Although some of his ideas fly in the face of traditional American dietary advice (but what is that anyway), the results of following his program are undeniable. I have been on the health and nutrition bandwagon for a long time and this book has helped me reach my weight loss goals better than anything else I have tried. I have lost 35 pounds in 3 months and feel great. It truly is a lifestyle change and re-education, not just another one of the countless fad diets that are out there. His program makes a lot of sense once you are willing to get past your own ego and the "logic" of the dietary advice that we have been misled with in this country for so long. Buy this book, check your ego at the door, and be read to lose weight and feel great!
Conflicts with much in recent understanding.......2006-11-02
For any author on nutrition to suggest that we start our day (and our metabolisms!) with little or nothing for breakfast automatically brings into question everything else in the book, unfortunately. The list of optimal foods per season is probably very good, but I was put off by the lack of metabolic common sense from the get-go.
Can Change Your Life.......2006-07-11
There are very few books that can actually change our life and this is one of them. It is one the most logical and simplistic ways to live healthly for the rest of your life. Just adpot these principles 51% of the time and you'll be set!
Enjoy! I sure did!
Great book!.......2001-10-22
As a person interested in nutrition and holistic approaches to health, I read and used concepts from this book and in my opinion it deserves a five start rating! The techniques the author presents work, and the plan is really easy to do. I lost weight and felt better incorporating the "large mid day meal" concept and it works well for my busy household to eat more lightly in the evening, not to mention my digestion. Sometimes I just have to depart from the "seasonal" concept of which foods to select (gotta have that almond butter!), but overall it makes good sense to eat what is in season...it is always fresher and tastier! His recommendations on arising earlier in the morning and going to sleep earlier at night are also solid basics to regain and keep ones health. This book is a definite keeper!
Average customer rating:
- Fairly entertaining book about scientific discovery.
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The Living Clock: The Orchestrator of Biological Rhythms
John D. Palmer
Manufacturer: Oxford University Press, USA
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ASIN: 019514340X |
Book Description
This book is an introduction to a basic property of life, one mostly unknown to science and the public until the latter half of the last century: Humans, plants, and animals have within their bodies a kind of clock that synchronizes much of what they do throughout their lives to the time of day and the seasons, and in the case of the sea-dwelling organisms, the tides. This timepiece performs its service autonomously - it rules silently within us without us giving a thought to it. Three chapters are devoted to the human clock: its disruptive action in transmeridional travel and shift work, its oversight in most every aspect of our physiology, and how doctors being aware of its action can save lives. Other major subjects describe the role in piloting birds in homing and migration, guiding the seasonal reproduction of plants and animals, and its influence on shore dwellers. The book closes with a description of the clockworks' escapement.
Customer Reviews:
Fairly entertaining book about scientific discovery........2003-07-18
Palmer explains that he wrote this book because so many people he encountered were interested in what he does as a marine biologist. In truth it is a book about scientific curiosity and the process of discovery. I won't give away the ending, found in the last chapter. Had Palmer's objective been an exposition on biological clocks, the last chapter would have been first. Unfortunately, I already knew what was in the last chapter, so my appreciation for the book was somewhat dulled. Still, it is a short, well written, fairly entertaining book. Palmer does an excellent job in describing experiments and making them interesting, and in showing how often a verification of the obvious led instead to new paths of discovery. Not least, while Palmer's sense of humor is not terribly creative, he can be fun.
Average customer rating:
|
Wide Awake at 3: 00 A.M.: By Choice or by Chance
Richard M. Coleman
Manufacturer: W H Freeman & Co (Sd)
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Binding: Paperback
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ASIN: 0716717964 |
Customer Reviews:
Bruce P Benyo.......2001-01-26
Most people who wrestle with getting to sleep on a regular basis are totally unaware that they are not really "insomniacs" at all! They just need to "adjust their internal clock." In Wide Awake at 3am, Dr Coleman brings real scientific research to bear on the twin problems of insomnia and sleep-deprivation. Bottom line... The book is extremely informative and entertaining. But the most thrilling part is this: 1)The descriptions of the problems caused by insomnia are exact, 2) the diagnoses put forth by Dr. Coleman make sense, and 3) the treatments proposed in the book really work! I would suggest this book to anyone who has problems with sleep or fatigue, even on an irregular basis.
Average customer rating:
- Practice the 20 minute break and reap the rewards
- Groundbreakingly great advice, 5 stars for usefulness...
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The Twenty Minute Break: Reduce Stress, Maximize Performance, Improve Health and Emotional Well-Being Using the New Science of Ultradian Rhythms
Rossi
Manufacturer: Tarcher
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Binding: Hardcover
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ASIN: 087477585X |
Customer Reviews:
Practice the 20 minute break and reap the rewards.......2004-02-21
I've been practicing the 20 minute break since November 2003, and it works for me. I believe it will help anyone who will take the time to practice it. It is a natural restorative state. I'm really glad I found this book.
Groundbreakingly great advice, 5 stars for usefulness..........2001-02-05
Despite its slow start and somewhat dull style, the dynamite content of this book is worth mining: What work habits do Winston Churchill and Steven Hawking share that helped make them incredible acheivers? How can a simple 20 minute break (two or three times a day) profoundly affect creativity, productiveness, body fat storage, and problem solving?
A long time ago I read somewhere that the British army once made record time over some incredible journey on foot by the simple trick of resting many short times each day. I've often pondered how to apply this to my own marathon workaholic style and this book is the answer I sought. Attention workaholics - this book is for you.
What absolutely free and painless thing can we do to work smarter, think better, boost creativity, and lose weight? The answer (and the scientific evidence) is right here. My guess is that techniques described here will massively boost productivity - and health! But my fear is that this man and his theories are ahead of his time. And his lackluster writing style will fail to start the revolution to this "tortoise" style of winning life's race to achievement and health.
Highly recommended for content, this book's only flaws are style and organization (surprising from publisher Jeremy Tarcher). Somebody else will probably rewrite this info into a bestseller. But if you're ready for some terrific advice now - be ahead of the crowd - buy this and read it. Life changing.
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