Chemistry for Today: General, Organic, and Biochemistry

Average customer rating:

Easy to read and understand.

This is not a good textbook

Frustrating

it isn't the best

Chemistry for Today: General, Organic, and Biochemistry
Spencer L. Seager , and Michael R. Slabaugh
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Hardcover

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Study Guide and Solutions Manual for Seager/Slabaugh's Chemistry for Today: General, Organic, and Biochemistry, 5th

Safety Scale Laboratory Experiments for Chemistry For Today: General, Organic, and Biochemistry

Organic and Biochemistry for Today (with GOB ChemistryNOW and InfoTrac )

Human Physiology

Introductory Chemistry for Today (with GOB ChemistryNOW and InfoTrac )

Accessories:

Study Guide and Solutions Manual for Seager/Slabaugh's Chemistry for Today: General, Organic, and Biochemistry, 5th

Safety Scale Laboratory Experiments for Chemistry For Today: General, Organic, and Biochemistry

ASIN: 053439969X

Book Description

Distinguished by its superior allied health focus and integration of technology, Seager and Slabaugh's CHEMISTRY FOR TODAY: GENERAL, ORGANIC, and BIOCHEMISTRY, Fifth Edition continues to lead the market on both fronts through numerous allied health-related applications, examples, boxes, and a new Companion Web Site, GOB ChemistryNow?. In addition to the many resources found in GOB ChemistryNow, this powerful new Web site contains questions modeled after the "Nursing School and Allied Health Entrance Exams" and NCLEX-LPN "Certification Exams." The authors strive to dispel users' inherent fear of chemistry and to instill an appreciation for the role chemistry plays in our daily lives through a rich pedagogical structure and an accessible writing style that provides lucid explanations. In addition, Seager and Slabaugh's CHEMISTRY FOR TODAY, Fifth Edition, provides greater support in both problem-solving and critical-thinking skills. By demonstrating how this information will be important to a reader's future career and providing important career information online, the authors not only help readers to set goals but also to focus on achieving them.

Customer Reviews:

Easy to read and understand. .......2007-02-12

In very good condition. Delivered according to schedule as promised

This is not a good textbook.......2006-12-17

I am not finding this textbook helpful whatsoever. I am in a prenursing program at Mills College. Explanations are not thorough and I need frequent help through private tutoring, other chemistry help books and textbooks, workshops. The questions at the end of the chapter asked are not even discussed within the text. It should be understood that the majority of people entering the health field especially nursing are resumers and have not touched chemistry in decades. At least that is the case in my program, it seems like a lot of them are resumers.
More explanations needed. More basic background needed. More examples. Corrections needed to be made for the problems. Plus if the problems are tricky then they should not be in black but in red. A lot of inconsistencies.
The online website program needs to be improved with more interactive demonstrations, videos etc.
I took intro to chem with this book and now i have to take survey of chem with organ and biochem next semester with it.

Frustrating.......2006-04-24

The explanations provided in this text book are decent; although, on occasions the book's breadth is insufficient. Unfortunately, the answer keys and test questions that accompany this text are riddled with inaccuracies. After my Organic Chemistry class gets back each test, we spend a half hour eliminating faulty questions. Further, while this book is egregiously expensive, one must pay extra to access the online features.

it isn't the best.......2000-03-31

This book have a traditional approach, dont take anything new. Your price is very high.

Pablo A. Pereira B. Sc. Pharm

Average customer rating:

Great Non-majors Book

Introduction to General, Organic and Biochemistry (with CD-ROM and ThomsonNOW Printed Access Card)
Frederick A. Bettelheim , William H. Brown , Mary K. Campbell , and Shawn O. Farrell
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Hardcover

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Labratory Experiments for General, Organic and Biochemistry (Brooks/Cole Laboratory Series for General Chemistry)

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Study Guide for Bettelheim/Brown/Campbell/Farrell's Introduction to Organic and Biochemistry, 8th

Human Anatomy with OLC bind-in card

Introduction to Radiologic Sciences and Patient Care

Accessories:

Student Solutions Manual for Bettelheim/Brown/March's Introduction to Organic and Biochemistry, 8th

Study Guide for Bettelheim/Brown/Campbell/Farrell's Introduction to Organic and Biochemistry, 8th

ASIN: 0495011975

Book Description

This best-selling GOB text continues to lead the way with a strong focus on current issues, pedagogically rich framework, a wide variety of medical and biological applications, visually dynamic art program, and exceptionally strong and varied end-of-chapter problems. Plus, this edition includes numerous new resources to help students' understanding and comprehension of chemistry, including full integration with our popular technological tools OWL (online homework management system) and GOBNow (student assessment program), completely updated biochemistry content, and expanded medical and health applications useful for allied health students.

Customer Reviews:

Great Non-majors Book.......2006-04-16

This book is in its 8th Edition with two new authors. The style continues the high standards set in the previous edition. I find this book to be a very good quick reference guide for chemical reactions, stoichiometry, organic and biological chemistry. I am very sad to see that Bettelheim and March have passed away!

Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding

Average customer rating:

A lot of information, but not-so-well explained...
Highly recommend it
essential
Biochemists Can't Miss
The Mother of All Enzyme Books

Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding
Alan Fersht
Manufacturer: W. H. Freeman
ProductGroup: Book
Binding: Hardcover

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ASIN: 0716732688

Customer Reviews:

A lot of information, but not-so-well explained..........2005-04-13

With an undergrad degree in chemistry and a year of graduate school (granted, without a focus solely in biochemistry), this text was often difficult for me to follow and gain much from. Though the text contained an impressive breadth of topics, this breadth came at the cost of depth. In my opinion, a textbook should more-or-less stand on its own in providing a clear understanding of a topic. All too often I didn't find this to be the case with the Fersht book. Instead, I often had to consult many of the references listed in the text to obtain sufficient understanding of topics. (Fortunately, the book includes extensive reference lists.) If looking up endless references (many old and sometimes difficult to obtain) is something you enjoy, this book is for you.--If not, forget it!

Highly recommend it.......2003-08-31

Hands down the bible of enzyme kinetics!

Anyone looking to learn more about enzyme kinetics, thermodynamics, structure, and function will find this book clear, thoughtfully written, and at the forefront in the field.

essential.......2002-05-01

If you are studying protein structure, you probably should read this book for reference.

This is solely my opinion, but I have learned new things and reinforced some old knowledge, as well. The book is well-written, and understandable, without being simplistic.

Some texts are difficult to understand, or dry, or facile. This is not one of those texts.

Biochemists Can't Miss.......2001-08-23

The book focuses on enzyme catalysis, stereochemistry of enzyme reactions, determination of rate constant, enzyme kinetics, and protein structure and folding. It would be an ideal reference for the study of protein chemistry. It can serve as the primary text for an advanced course in protein chemistry or a supplement for undergraduate biochemistry text.

Protein folding has remained one of the most intricate yet less understood process in modern biochemistry. Feersht's treatise of the subject in this book is splendid. The author overviews protein structure and diversity in the opening chapter. What I find really precious about this book is the discussion on protein engineering, forces on folding, and recombinant DNA technology in the context of protein folding.

Aside from protein chemistry, the chapter on chemical catalysis is excellent in learning more about transition state theory, general acid/base catalysis, covalent catalysis, structure-reactivity relationships, and kinetic isotope effects.

The Mother of All Enzyme Books.......2001-01-10

Man, this book rocked! I took one look at the ribbon structure of ATPase on the cover and said to myself, "Whoa dude! This is, like, phat!" Then I turned the pages and BAM! I was knee deep in protein structure! Like, any first-year biochemist knows its all about the acids, as in amino, and Fersht, he knows his peptides! Oh man, I was on cloud nine! And I've been off my meds for two months now! But you wanna know the real dope? You can't say diddly about function unless you know structure, and that Alan, as in Fersht, dude! Like, he starts you off simple, like, you know, with the "building blocks," like we're a bunch of two-year-olds, and you string 'em together and get all that higher-order structure and stuff, and slowly, ever so slowly, like a mental itch that invades your consciousness and becomes screaming voices telling you to AHHHHHHHHH! So many domains! Too many functional units! No, no, nooooooo! Schiff base? Shift Bass! Ah HA HA HA HA! What do all those K's mean!?! Take me home! Please...

Fundamentals of General, Organic, and Biological Chemistry

Average customer rating:

Thanks very much!
not the product I ordered
Well Written
Excellent Textbook
Excellent Book on Physiological Chemistry

Fundamentals of General, Organic, and Biological Chemistry
John McMurry , Mary E. Castellion , and David S. Ballantine
Manufacturer: Prentice Hall
ProductGroup: Book
Binding: Hardcover

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ASIN: 0131877488

Book Description

Rewritten throughout for enhanced clarity and readability – without sacrificing content – this best-seller offers a focus on problem-solving and engaging discussions of relevant applications. Effectively covers the essentials of allied health chemistry without excessive and unnecessary detail. Puts chemistry in the context of everyday life. Covers biochemistry thoroughly to allow for flexible treatment and places emphasis on its relevance to society. Updates and expands content throughout in topics such as DNA, genomics, chemical messengers, the new food pyramid, and the modern view of nucleic acid chemistry and protein synthesis. Revises illustrations throughout for increased effectiveness. Redesigned diagrams and bulleted lists for a clearer layout. A useful resource for anyone working in the fields of nursing, physical therapy, agriculture, home economics, aquaculture – or those who simply have a desire to learn more about the basic concepts of chemistry and biochemistry.

Customer Reviews:

Thanks very much!.......2007-07-05

It's a great edition of the book, and I appreciate it very much! I'm very happy with the shipping and condition of the book, and it was great overall!

not the product I ordered.......2007-04-03

I wanted to order the book, but when I recieved it, it was the wrong edition! Thanks for the honesty!

Well Written.......2007-01-05

The book was used for 90% of my class. It well written for the student with little exposure to chemistry. The pictures and diagrams could have better depicted the subject matter. The price was $40 less than what my college bookstore charges. Great value.

Excellent Textbook.......2006-04-19

This is an excellent textbook for a two semester course in General, Organic, and Biological Chemistry for Health Professions. It does a very good job of explaining the concepts of General, Organic, and Biological Chemistry. It also has excellent applications on disease processes and pathophysiology. The organization of each chapter is a plus. I highly recommend this textbook. It is number one!

Excellent Book on Physiological Chemistry.......2006-03-05

This book is exactly as described by the publisher. A very readable overview of general and organic chemistry. A comprehensive study of the organic molecules and chemical processes specific to the human body.

I liked this book so much that I'm ordering a hardcover copy to replace my original paperback edition.

Glycoscience: Chemistry & Chemical Biology 3 Volume Set (With CD-ROM)

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Glycoscience: Chemistry & Chemical Biology 3 Volume Set (With CD-ROM)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 354067764X

Book Description

Glycostructures play a highly diverse and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them, but many facts still remain undiscovered. "All roads lead to carbohydrates ... we cannot do without them." (K.C. Nicolaou). Presently the field is experiencing a "quantum jump". Therefore the editors have drawn together in this three volume set plus an accompanying CD-ROM, the complete and up-to-date information on glycostructures, their chemistry and chemical biology, and present them in the form of a comprehensive and strictly systematic survey. The texts are furnished by 2.670 figures, chemical structures and reaction schemes (including more than 12.000 individual chemical reactions), and more than 9.000 references.

Darwin's Black Box: The Biochemical Challenge to Evolution

Average customer rating:

A Design Parade
A great critique of evolution.
Behe's empty box
Amazing stuff
Wonderful

Darwin's Black Box: The Biochemical Challenge to Evolution
Michael J. Behe
Manufacturer: Free Press
ProductGroup: Book
Binding: Paperback

Biochemistry | Biological Sciences | Science | Subjects | Books

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ASIN: 0743290313

Amazon.com

Michael J. Behe, a biochemist at Lehigh University, presents here a scientific argument for the existence of God. Examining the evolutionary theory of the origins of life, he can go part of the way with Darwin--he accepts the idea that species have been differentiated by the mechanism of natural selection from a common ancestor. But he thinks that the essential randomness of this process can explain evolutionary development only at the macro level, not at the micro level of his expertise. Within the biochemistry of living cells, he argues, life is "irreducibly complex." This is the last black box to be opened, the end of the road for science. Faced with complexity at this level, Behe suggests that it can only be the product of "intelligent design."

Book Description

The groundbreaking, "seminal work" (Time) on intelligent design that dares to ask, was Darwin wrong?

In 1996, Darwin's Black Box helped to launch the intelligent design movement: the argument that nature exhibits evidence of design, beyond Darwinian randomness. It sparked a national debate on evolution, which continues to intensify across the country. From one end of the spectrum to the other, Darwin's Black Box has established itself as the key intelligent design text -- the one argument that must be addressed in order to determine whether Darwinian evolution is sufficient to explain life as we know it.

In a major new Afterword for this edition, Behe explains that the complexity discovered by microbiologists has dramatically increased since the book was first published. That complexity is a continuing challenge to Darwinism, and evolutionists have had no success at explaining it. Darwin's Black Box is more important today than ever.

Download Description

From within the highest ranks of the scientific community comes a startling new theory of creation that not only contradicts Darwinian orthodoxy but opens the door to theological arguments biologists have dismissed and ridiculed for more than a century.

Customer Reviews:

A Design Parade.......2007-10-08

After I purchased biochemist Michael Behe's new book "The Edge of Evolution," I decided it would be wise for me to boney up on his seminal 1996 work "Darwin's Black Box." I already played muck-a-muck with this debate for quite a few months, in a whirling attempt of absorbed concentration in the infamous struggle of "Design v. Darwin" to find out the truth. The debate may be superfluous, and especially downright nasty, and it will continue to intensify in the coming months with a new documentary by lawyer and social commentator Ben Stein in February 2008. Reading Behe is like taking a time out from the unfair play on both sides of the field. He is a better penman than Richard Dawkins, devoid of the man's vile poison, and he treats the reader as a student to be respected, not as a clay figure to be molded into a Darwiniac inquisitor. In fact, Behe is a committed believer in common descent, a position that isn't too friendly a bedfellow of creationists. The book is unique in both its author and its content, as demonstrated by the numerous "critiques" and "debunking" of the arguments proposed on the Amazon boards. Reading the hundreds or so reviews and responses only do so much to strengthen Behe's ideas.

This book is more like a parade. Behe, the ringleader with the marching rod, introduces us to the central argument of the "Black Box." It turns out to be irreducible complexity, which embodies the fabric of many biological systems once believed to be inconsequential, simplistic globules developed by chance mutation and selection. We then witness the march of the band and its many sections: the cell, the bacterial flagellum, blood-clotting, the cilium, etc. Each system, composed of many interdependent parts, will cease functioning if only one of its microscopic parts is missing. The individual parts, of course, can still possibly perform some other function (so goes the most powerful critique against ID! Things have different functions! Eureka!). However, the system itself will be quite useless. Thus appears the grand finale, a prolonged beat of the bass drum, which is that the neo-Darwinian paradigm is an implausible explanation for how these molecular systems appeared, no matter how many billions of years you attempt to postulate for its progress.

Attacking the hypothesis of intelligent design as a "God-of-the-Gaps" argument is one of the most frequently peddled mischaracterizations in all of the debate, promoted by no less than the most rabid of atheistic biologists like Dawkins and Eugenie Scott. The argument goes: We cannot envision a way naturalistic science could develop this system; hence it was made by God. The falsehood in this attack is typical, not to mention simplistic. Behe himself describes ID as the purposeful arrangement of parts in a system. We see this in every biological system: the cell, the flagellum, the cilium, and the blood clotting system. These systems are arranged in a purposeful pattern, structured precisely to, in the case of the cell, to replicate and store information, and in the case of other biological organisms, to sustain itself (unlike non-living materials like, say, rocks). It says nothing about whom or what this designer is. And, of course, it still remains the burden of proof to demonstrate how it evolved. We're talking about the Supreme Law of the Universe (Darwinism), and all that people can come up with are fairy tales about how it MIGHT have happened?

Neo-Darwinism cannot be supported much longer. It doesn't mean that evolution did not occur, or that common descent is a bogus idea. But the chance mutation-selection paradigm is becoming increasingly to difficult to sustain. The hyperactive Stalinist response to events like the Dover case and the actions committed by groups like the NSTA and ASE in America suggests a religious cult going through panic mode. Certainly there is something to what Behe and the rest of the ID movement is saying that just strikes a nerve. Maybe it's just the truth.

A great critique of evolution........2007-09-25

Supporters of the classic evolution that is taught in schools went nuts when this book was published. It could be argued that Michael Behe started the inteligent design theory and brought the debate of evolution back public stage.

Behe has been heavily criticized for daring to confront the evolution juggernaught and has made his book a must read for anyone interested in the evolution debate. This book is important and will shape the thinking of evolutionary scientists in the future, whether they like it or not.

Behe's empty box.......2007-09-05

First let's start with a quote from The National Academy of Science. " Creationism, I.D. and other claims of supernatural intervention in the origin of life of species are not science because they are not testable by the methods of science."

Mr. Behe uses the terms darwinism, darwinian evolution, darwinian gradualism through-out his book instead of modern evolution because he knows this name carries alot of heated imagery in the minds of the fundamentalist. If confronted with the findings of modern day evolution I think Mr. Behe would realize just how shakey the ground for his ideas would become.
He condems Prof. Doolittle for using a "yin yang" analogy but goes on to give boring and irrealivant analogy after analogy of his own.
He states that 90 persent of Americans believe in God as if the truth were dictated by a show of hands. If that were true then he might want to convert to Islam since the Muslim faith is the largest religious group in the world.
This leads me to my next problem with Mr. Behe's book. He is constantly refering to an intelligent designer or intelligent agent, and then speaking of the supernatural and divine. Here I have two questions.
1. Why use the singular noun? Why not appeal to many intelligent designers or agents?
2. Why could'nt these creators be "natural" as opposed to supernatural?

Which leads me to my final gripe.
Mr. Behe is constantly telling us how the scientific evidence points to an intelligent designer but never offers his own testable proof. Complexity is not proof in and of itself. What is the indentity of this creator? He does'nt say. The whole book seemed to be a rant against scientist who do not agree with his view. Mr. Behe seems to think there's this big conspiracy against the truth. Who's truth? His.

Amazing stuff.......2007-08-31

Functionally interdependent irreducible complexities....fascinating. How can these be adequately explained? I find it truly amazing.

Wonderful.......2007-08-22

Down to earth with complexity explained in a simple readable way. This is a very good source to dispute one of the most absurd notions in the history of the world....evolution. Fantastic, logical, and full of expert knowledge. Dispute it if you wish, but truth is evident. God is real!

Organic Structure Analysis (Topics in Organic Chemistry)

Average customer rating:

Organic Spectroscopy Made Clear

Organic Structure Analysis (Topics in Organic Chemistry)
Phillip Crews , Jaime Rodriguez , and Marcel Jaspars
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

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ASIN: 0195101022

Book Description

Organic Structure Analysis is an ideal text for upper-level undergraduate and first-year graduate courses in organic spectroscopy. It provides students with the background necessary to effectively apply spectroscopic data in establishing features of molecular structure. Unique in its coverage, it is the only text that emphasizes strategies, interpretation, modern techniques, and problem solving. The text's major aim is to show how spectra can be efficiently examined in order to identify a molecule's major structural elements. It focuses on four techniques which are used on a day-to-day basis by most organic chemists: nuclear magnetic resonance (NMR), mass spectroscopy (MS), infrared (IR), and ultraviolet-visible (UV-VIS). Each chapter provides different perspectives on using spectroscopic data in a step-by-step process to establish structural features such as an overall carbon framework; the presence and location of functional groups; the regiochemistry and stereochemistry of substituents; and, finally, the absolute stereochemistry of chiral centers. Recent advances in NMR and MS have changed the way these components are introduced and used in organic spectroscopy courses. Unlike similar texts, this book provides ample, up-to-date coverage of the latest developments in NMR and MS techniques. Organic Structure Analysis adopts a practical approach to the subject which emphasizes building experience; the authors recognize that a combination of problem solving, access to data from models, and understanding the rules of spectral interpretation helps students to build expertise in structure determination from spectra. It outlines elements of theory, but with an emphasis on those directly relevant to spectral interpretation. The text is divided into three major sections; the first section provides extensive coverage of each of the individual methods, the second section illustrates how the strategies of organic structure are actually applied in ten problems whose solutions are provided, and the third section consists of fifty unsolved problems which range from simple monofunctional compounds to complex natural products.

Customer Reviews:

Organic Spectroscopy Made Clear.......2001-08-24

Crews is not a hardcore treatise of the subject. It does not cover the quantum mechanics behind spectroscopy and the complicated mathematical underneath the concept. Instead it discusses the fundamentals and results of such quantum calculations which apply to identification of organic compounds. Basic concepts of nuclear magnetic resonance, infrared spectroscopy, ultra violet spectroscopy are thoroughly covered with examples and charts. Crews is a splendidly-written, straight-forward work that would be suitable for advanced undergraduates who had finished at least one year of organic chemistry, for those who pursue chemical research, and entering grad students.

Synthesis and Applications of Isotopically Labelled Compounds, Volume 7

Average customer rating:

Synthesis and Applications of Isotopically Labelled Compounds, Volume 7

Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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Book Description

This outstanding book covers the most recent advances in the production of stable and radioactive isotopes as well as in the synthesis, analysis and applications of isotopically labelled compounds. Written by internationally renowned contributors, it provides authoritative and wide-ranging coverage of significant growth areas including:

new methodologies in the production of isotopes
novel approaches to compounds labelled with isotopes of hydrogen, carbon and other stable, long-lived and short-lived radioactive isotopes
advances in the analysis of istopically labelled compounds
recent and future applications of isotopes in pharmaceutical research and development, in pharmacological and clinical sutdies and nuclear medicine, as well as in agricultural, nutritional and environmental research
recent applications of isotopes in investigating organic and bioorganic mechanisms and pathways
safety and regulations of handling isotopes

This will be an invaluable information and reference source to anyone involved in the production of isotopes, the synthesis and analysis of compounds labelled with stable, long-lived or short-lived radioactive isotopes, in drug research and development, in clinical investigations and nuclear medicine, in agricultural research and development and environmental investigations, in the elucidation of biological and chemical pathways, handling radioisotopes, laboratory design and other areas.

The Organic Chemistry of Drug Design and Drug Action, Second Edition

Average customer rating:

Good book with few flaws
Outstanding...
Excellent
Check out the new edition of this book
Compulsory book for every biochemistry student

The Organic Chemistry of Drug Design and Drug Action, Second Edition
Richard B. Silverman
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0126437327

Book Description

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that rationalize drug action and allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and now includes color illustrations, chapter problems, and other elements that make concepts easier to understand.

* Organic chemist's perspective of how drugs are designed and function
* Teaches organic chemists and biochemists the fundamentals of drug design and drug action using drugs as examples
* Extensive use of references to the primary and secondary literature for more in depth reading about all concepts
* Extensive use of structures, schemes, and figures to illustrate points
* Explanations of dual-acting drugs
* Problem sets and answers for each topic
* Casual writing style
* Author has published over 200 articles in the areas of synthesis, bioorganic chemistry, and medicinal chemistry, has been awarded 21 patents, and has invented a drug that is under consideration for commercialization.

Customer Reviews:

Good book with few flaws.......2007-01-09

The book is great for understanding the title subject. But it has too many references which distracts the reader. Also, many times, the corresponding picture of a particular topic covered is not in the same page as the topic. This requires going back and forth between pages. The problems at the end of each chapter are really good and checks the understanding of the subject thoroughly.

Outstanding..........2005-05-06

This is probably the best book of its kind in the vast and multidisciplinary field of drug design and action. Richard Silverman is an acclaimed chemistry Professor at Northwestern University, and in this book, he provides the most comprehensive and lucid exposition of the chemical basis of drug action that I have seen. No matter how complicated biological systems and their interactions are, at the basic level, it's all chemistry, and mostly organic chemistry. An organic chemist will find this book extremely illuminating in a way that would not have been made clear through his traditional education.
The book opens with a short but clear discussion of drug discovery, combinatorial chemistry, and clinical testing and trials. Then it leads the reader through a variety of enzyme catalyzed reactions, with examples of major drugs studded all the way. Silverman shows us how nature is the master organic chemist, employing the familiar reactions of chemistry in an unsurpassed way. The chapter on enzyme inhibition is long and detailed, and it's breathtaking. Which is important because almost all major drugs act by inhibiting enzymes. The examples which Silverman chooses to illustrate are both important (including many bestselling anti-cancer, anti-viral, and antibiotic drugs to name a few), as well as very interesting. The last parts of the book deal with DNA binding drugs, and with pathways of drug metabolism and excretion. Along all the way, the emphasis is on the chemical reactions that drugs undergo, which after all is what controls their properties. The lucidity of the book is such that a beginning graduate well-versed with the basic principles of general and organic chemistry can easily understand all the contents.
This book is so interesting and illuminating that it's one of the very few academic books which I have actually read from the first to the last page, with every word in between. In fact, it even makes great bedside reading! Truly a must-have book for all chemists and biologists of every kind, interested in how drugs work.

Excellent.......2004-04-05

This is an excellent book and it lies on the smaller physical side of organic chemistry, as the title says, instead of the huge biochemical side. It really was a fascinating book.

Check out the new edition of this book.......2004-02-04

There is a new considerably expanded and updated edition available of Silverman's already classic text as of Jan/04. ISBN is 0-12-643732-7. Check it out... price is comparable to the earlier edition.

Compulsory book for every biochemistry student.......2001-04-20

This book is very good introduction in the major aspects of the chemistry of the drugs. It explains with good schemes the reactions of drugs and others important mechanisms. The book is scientifically well written and enjouyable to read. The graphic images of molecules integrate well with the written aspects of book. Book covers major areas of pharmaceutical drug research, integrates the chemical and pharmacological aspects of drugs, and discusses the essentials of drug activity and mechanisms.

Essentials of General, Organic, and Biochemistry (with CD-ROM)

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exactly perfect for the new student

Essentials of General, Organic, and Biochemistry (with CD-ROM)
Melvin T. Armold
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Hardcover

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