Gold and Silver Staining: Techniques in Molecular Morphology (Advances in Pathology, Microscopy, & Molecular Morphology)

Book Description

Immunogold silver staining is one of the most sensitive techniques available for visualizing the location of antibodies and nucleotide probes that have been bounded to specific antigens or to nucleotide sequences. As gold and silver staining continues to advance research in molecular morphology, this book presents the information you need to know about the various staining methods, their useful applications, and the advantages and drawbacks of each process. Gold and Silver Staining: Techniques in Molecular Morphology provides a timely description of approaches, methods, protocols, and applications. The contributors cover the latest developments and a wide range of applications from highly sensitive detection of antigens to single copy detection of DNA and RNA. Some of the authors are "living legends" in the field and bring their expertise and experience to this fine collaboration. Written in one consistent style, each chapter includes a concise, but comprehensive introduction, step-by-step protocols with technical hints, and a discussion of results and critical steps. What differentiates this book from all others like it, is the status of the editors, who have worked on this technique from its inception and have produced innumerable publications on the topic. The other distinguishing feature is that all of the contributors are amongst the absolute foremost leaders from the United States and Europe. Gold and Silver Staining: Techniques in Molecular Morphology presents a complete overview and detailed descriptions of this technique that allows the visualization of molecules that have never been localized before and with hitherto unknown sensitivity. Not only does this book provide an excellent review of this field, but it also serves as a lab manual for those who want to carry out this technique in their laboratory and clinical work. Armed with this information, advances in this powerful field of research will ensue.

Molecular Chemistry of the Transition Elements: An Introductory Course

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Molecular Chemistry of the Transition Elements: An Introductory Course
François Mathey , and Alain Sevin
Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Hardcover

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Organic Chemistry

ASIN: 0471959197

Book Description

Using a systematic and theoretical approach, this outstanding textbook offers a succinct introduction to the underlying principles of organometallic chemistry--with a strong emphasis on reactions mechanisms. It links theory with the chemical properties of the compounds, enabling students to classify the variety of compounds and to understand the basic reaction mechanisms of diverse classes of compounds. Chapters with selected applications help students to transfer the theoretical knowledge to real life chemistry. Contains numerous examples.

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Very useful text
...a practical book

Physical Vapor Deposition of Thin Films
John E. Mahan
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471330019

Book Description

A unified treatment of the theories, data, and technologies underlying physical vapor deposition methods With electronic, optical, and magnetic coating technologies increasingly dominating manufacturing in the high-tech industries, there is a growing need for expertise in physical vapor deposition of thin films. This important new work provides researchers and engineers in this field with the information they need to tackle thin film processes in the real world. Presenting a cohesive, thoroughly developed treatment of both fundamental and applied topics, Physical Vapor Deposition of Thin Films incorporates many critical results from across the literature as it imparts a working knowledge of a variety of present-day techniques. Numerous worked examples, extensive references, and more than 100 illustrations and photographs accompany coverage of:
* Thermal evaporation, sputtering, and pulsed laser deposition techniques
* Key theories and phenomena, including the kinetic theory of gases, adsorption and condensation, high-vacuum pumping dynamics, and sputtering discharges
* Trends in sputter yield data and a new simplified collisional model of sputter yield for pure element targets
* Quantitative models for film deposition rate, thickness profiles, and thermalization of the sputtered beam

Customer Reviews:

Very useful text.......2007-05-03

I found this book very useful and practical. It is nice to see a book that balances a good combination of theory and practicality.

...a practical book.......2005-09-14

This book is more practical than theoretical... It include the basic concepts of vacuum and practical plasmas (like sputering plasma... I like it becouse there are many numerical examples to apply the ecuations and to explain the fundamentals of plasma modelling. It is a basic book

The Transuranium People: The Inside Story

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A look at the People behind the Atoms
A partisan history of the heaviest elements

The Transuranium People: The Inside Story
Darleane C. Hoffman , and Albert Ghiorso
Manufacturer: World Scientific Publishing Company
ProductGroup: Book
Binding: Hardcover

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ASIN: 1860940870

Book Description

In this highly interesting book, three pioneering investigators provide an account of the discovery and investigation of the nuclear and chemical properties of the twenty presently known transuranium elements. The neutron irradiation of uranium led to the discovery of nuclear fission in 1938 and then to the first transuranium element, neptunium (atomic number 93), in 1940. Plutonium (94) quickly followed and the next nine elements completed the actinide series by 1961. Investigation of the chemical properties of the actinides was followed more recently by chemical studies of the first three transactinides - rutherfordium (104), hahnium (105), and seaborgium (106). Recent discoveries have extended the known elements to 112.

Customer Reviews:

A look at the People behind the Atoms.......2005-09-25

This is truly a facinating book about real people, not 2-dimensional facts on paper. The people leading the work to create and then discover man-made atoms, written by the people themselves.

A wonderful insight into the lives, trials, and tribulations -- as well as the joys, excitement, and successes of these people.

Having known Glenn Seaborg, and knowing Darleane Hoffman, I can hear their personality and excitement for their work bubble through the pages of this book.

Recommended for anyone with an interest in the history of science, regardless of whether you are professionally engaged in the field, or just an interested reader.

A partisan history of the heaviest elements.......2001-01-10

Lawrence Berkeley National Laboratory and its predecessor organizations have been home to the discovery of more elements with atomic number greater than 92 than anyplace else in the world, beginning in 1940 with the discovery of element 93, neptunium, by Edwin McMillan and Philip Abelson at the University of California's Radiation Laboratory.

Not all these achievements were undisputed, and the arguments are far from settled. Although many of the issues are not matters a nonspecialist can judge, a lively sense of history still unfolding is one of this book's fascinations. In addition to the volume's official page count, there are an extra 93 pages of front matter -- most of it a long preface titled "Intimate glimpses of the authors' early lives," which is an intriguing minivolume in itself.

Of Darleane Hoffman, winner of the American Chemical Society's Joseph Priestley medal, we learn that in 1952 the personnel department at Los Alamos ruined her chance to participate in the discovery of elements 99 and 100 (einsteinium and fermium). Arriving from Oak Ridge to take up a job in the short-handed radiochemistry group there, Hoffman was told that "we don't hire women in that Division." What's more, her security clearance had somehow been "lost." Meanwhile, in November, new elements had been produced in the world's first thermonuclear explosion, and in December and January they were separated from coral debris from the test site. The personnel-department snafu wasn't cleared up until March.

In 1941 Albert Ghiorso, who worked in the San Francisco Bay Area during the Depression for a supplier of ham radio equipment, was sent to the U.C. Rad Lab to hook up an intercom for the secretaries and to build some Geiger counters. "I was not told that it would be necessary to build hundreds of these devices for Prof. Glenn T. Seaborg's group." By way of consolation, he married one of the secretaries, Wilma Belt.

When Seaborg went to Chicago to join the Manhattan Project's Metallurgical Laboratory, he asked Ghiorso to come along. Although Ghiorso barely knew Seaborg, he agreed on condition "that I not be asked to build any more G-M [Geiger-Mueller] circuits." Later he learned that Wilma and Helen Griggs, Ernest Lawrence's secretary (soon to be Mrs. Seaborg), had decided between them that Ghiorso belonged in Chicago. There he was to play a crucial role.

Seaborg's life is more familiar than those of his coauthors, but it is interesting to see events usually viewed through the lens of a sometimes grim history -- his discovery of plutonium, his work on the Manhattan Project, later his Nobel Prize, and his chairmanship of the Atomic Energy Commission during the Kennedy years -- from the fresh perspective of a chemist's fascination with unexplored scientific terrain.

Much of The Transuranium People is grouped into chapters describing the quest for new elements which often came in pairs -- neptunium and plutonium, americium and curium, berkelium and californium, and so on -- for reasons having to do with particular experimental methods or available energies.

Competition, controversy, and compromise were part of the quest from the beginning. In an intriguing chapter called "Naming controversies and the Transfermium Working Group," the authors recount a quarter-century of unsuccessful attempts to end the "dissent and confusion" surrounding credit for discoveries of elements 101 through 109. Element 105 occasioned the worst clash. The authors contend that researchers at the Joint Institute for Nuclear Research at Dubna in Russia could not, as they claimed, have isolated element 105 in 1967 by the means described; a different isotope of 105 was made in 1970 at Lawrence Berkeley Lab's HILAC by Ghiorso and four colleagues, who named it hahnium.

Not until 1997 was a compromise reached by the International Union of Pure and Applied Chemistry, naming 105 dubnium and at the same time accepting the name seaborgium for element 106 -- "in the interest of international harmony," as the American Chemical Society's Committee on Nomenclature put it. In this book 105 is called hahnium, the name by which it was best known for a quarter century.

The Transuranium People also includes an illuminating discussion of the excitement behind the search for "superheavy elements," those whose stability should increase with increasing atomic weight, notably the possibility that elements in "a 'Magic Island' or 'Island of Stability' with half-lives as long as a billion years might exist."

If so, they might be found in nature. But looking for an element "whose atomic number and chemistry I could only guess at seemed nearly impossible," Hoffman states, although in 1971 she had succeeded in separating minute amounts of plutonium from natural ores. Indeed all such searches have failed.

Instead, superheavies have been produced in accelerators. In 1999 Victor Ninov, Kenneth Gregorich, and their colleagues, working at Berkeley Lab's 88-Inch Cyclotron, created elements 118 and 116. A few months earlier, researchers working at Dubna had reported finding element 114; no one has yet laid claim to 113, 115, or 117. The quest continues -- especially for those with the right number of neutrons and protons to form "magically" stable atoms.

Book Description

Low-dimensional solids are of fundamental interest in materials science due to their anisotropic properties. Written not only for experts in the field, this book explains the important concepts behind their physics and surveys the most interesting one-dimensional systems and discusses their present and emerging applications in molecular scale electronics. The second edition of this successful book has been completely revised to include the remarkable achievements of the last ten years of research and applications. Chemists, polymer and materials scientists as well as students will find this book a very readable introduction to the solid-state physics of electronic materials.

Electron Paramagnetic Resonance of Transition Ions

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Electron Paramagnetic Resonance of Transition Ions
A. Abraham , and Betty Isabelle Bleaney
Manufacturer: Dover Pubns
ProductGroup: Book
Binding: Paperback

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Metal Vapour Lasers: Physics, Engineering and Applications

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Metal Vapour Lasers: Physics, Engineering and Applications
Christopher E. Little
Manufacturer: Wiley
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471973874

Book Description

Metal Vapour Lasers Christopher E. Little University of St Andrews, St Andrews, Scotland Since the first successful demonstration of a metal vapour laser (MVL) in 1962, this class of laser has become widely used in a broad range of fields including precision materials processing, isotope separation and medicine. The MVLs that are used today have a range of impressive characteristics that are not readily available using other technologies. In particular, the combination of high average output powers, pulse recurrence frequencies and beam quality available from green/yellow Cu vapour lasers (CVLs) and Cu bromide lasers, coupled with the high-quality, multiwatt ultraviolet (265-289 nm) radiation that can be produced using simple nonlinear optical techniques, means that Cu lasers will continue to be important for many years. Metal Vapour Lasers covers all the most commercially important and scientifically interesting pulsed and continuous wave (CW) gas-discharge MVLs, and includes device histories, operating characteristics, engineering, kinetics, commercial exploitation and applications. Short descriptions of gas discharges and excitation techniques make this volume self-consistent. A comprehensive bibliography is also provided. The greater part of this book is devoted to CVLs and their variants, including new sealed-off, high-power 'kinetically enhanced' CVLs and Cu bromide lasers. However, many other self-terminating MVLs are also discussed, including the red AuVL, green/infrared MnVL and infrared BaVL. Pulsed, high-gain, high average power lasers in the UV/violet (373.7, 430.5 nm) spectral regions are represented by Sr¯+ and Ca¯+ discharge-afterglow recombination lasers. The most commercially successful of the MVLs - the CW, UV/blue cataphoretic He-Cd¯+ ion laser - is described. Hollow cathode lasers are represented in two guises: 'white light' (blue/green/red) He-Cd¯+ ion lasers and UV/infrared Ne/He-Cu¯+ ion lasers. This unique volume is an essential reference source for all those working on metal vapour lasers, and all those who use them, from postgraduate students through to experienced scientists and engineers. It will also be extremely useful to all those working in other gas laser technologies, and in gas discharge physics.

Mesoscopic Materials and Clusters: Their Physical and Chemical Properties (Springer Series in Cluster Physics)

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Mesoscopic Materials and Clusters: Their Physical and Chemical Properties (Springer Series in Cluster Physics)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540648844

Book Description

Mesoscopic physics is a fast growing discipline with countless potential applications. Understanding the science of mesoscopic materials with unique physical and chemical properties is important for the design of nanodevices and materials with unique properties. Clusters as mesoscopic particles represent an intermediate state of matter between single atoms and solid material. This book deals with the properties of clusters in matrixes, on surfaces, and in vacuum. The formation and application of cluster-based materials is discussed. This book will appeal to physicists, chemists, materials researchers, and advanced students.

Molecular Orbitals of Transition Metal Complexes

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A Good Resource, but takes some effort to master

Molecular Orbitals of Transition Metal Complexes
Yves Jean
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

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Concepts and Models in Bioinorganic Chemistry

ASIN: 0198530935

Book Description

This book starts with the most elementary ideas of molecular orbital theory and leads the reader progressively to an understanding of the electronic structure, geometry and, in some cases, reactivity of transition metal complexes. The qualitative orbital approach, based on simple notions such as symmetry, overlap and electronegativity, is the focus of the presentation and a substantial part of the book is associated with the mechanics of the assembly of molecular orbital diagrams. The first chapter recalls the basis for electron counting in transition metal complexes. The main ligand fields (octahedral, square planar, tetrahedral, etc.) are studied in the second chapter and the structure of the "d block" is used to trace the relationships between the electronic structure and the geometry of the complexes. The third chapter studies the change in analysis when the ligands have pi-type interactions with the metal. All these ideas are then used in the fourth chapter to study a series of selected applications of varying complexity (e.g. structure and reactivity). The fifth chapter deals with the "isolobal analogy" which points out the resemblance between the molecular orbitals of inorganic and organic species and provides a bridge between these two subfields of chemistry. The last chapter is devoted to a presentation of basic Group Theory with applications to some of the complexes studied in the earlier chapters.

Customer Reviews:

A Good Resource, but takes some effort to master.......2006-07-18

This book was assigned for my introductory inorganic chemistry course at Caltech. Its strong points are that it covers most common inorganic complex shapes and derives their MO diagrams in a simple and easy-to-follow way. The exercises are also relatively well-written and contain answers. The caveat is that you have to do some work on the side to understand what is going on, and some diagrams could be better listed. For example, the LGOs are shown 150+ pages away (in the appendices) from where their relevant groups are discussed, and a brief introduction to the Huckel method would have been appreciated. The source of character tables could have been explained a bit more clearly as well, and there is little to no underlying derivation of the group theory (the words dihedral group, etc. are never mentioned). But all in all, it's an OK introduction.

Molecular Metals (Proceedings. ed By William E. Hatfield. Proc of the Conf Held Sept 10-16, 1978)

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Molecular Metals (Proceedings. ed By William E. Hatfield. Proc of the Conf Held Sept 10-16, 1978)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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