Strategic Applications of Named Reactions in Organic Synthesis

Book Description

Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist.

* The first reference work on named reactions to present colored schemes for easier understanding
* 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples
* An opening list of abbreviations includes both structures and chemical names
* Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works
* Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools
* Extensive index quickly locates information using words found in text and drawings

Customer Reviews:

Just Buy It........2007-09-18

To put it shortly, if you're an organic chemistry graduate student the just go ahead and buy this book. It will be the most used book in your personal library. Also, if you are an undergraduate working in a research lab buy it as well. You'll have a huge jump on the other graduate students when you go to grad school having been familiar with this book.

An invaluable reference source of organic chemistry.......2007-09-06

The Strategic Applications of Named Reactions in Organic Synthesis is constitute the largest group of organic compounds and are becoming ever more important in all aspects of strategic applications in mechanic of action organic synthesis in detail.hence,I read repeatly.I promoted to the organic chemistry from this text book.

Epic of reaction mechanism.......2007-05-10

This book is like an epic of reaction mechanism. When I read the book for the first time, I was tried to think about the mechanisms only but gradually I realized that application of these name reactions are more important than to remember. Real life mechanism applications are hard, but I am sure, if anybody can remember some of them that they referenced in the book will be great. So in one word, this book is awesome book that I ever read for reaction mechanism.

Necessary Named Reactions reference.......2007-05-05

This is the best named reactions book currently available to the organic chemist. Mechanistic detail is quite thorough, and i hope a second edition comes out in a few more years.

Strategic Applications of Named Reactions in Organic Synthesis.......2006-11-10

I just want to say that I'm really satisfied with the conditions of the book, the time that it took from the purchase until it arrives is acceptable. I'm going to start buying more from Amazon.com. I'm really happy with the service.

The book is very good. It gives a broad view of the reactions and then specific examples where these reactions were applied with the references.

The Art of Writing Reasonable Organic Reaction Mechanisms

Average customer rating:

basics for organic chemist
Excellent Book on Mechanisms
Money well spent.
Orgo Made Easy!
Surprisingly Easy to Read and Understand

The Art of Writing Reasonable Organic Reaction Mechanisms
Robert B. Grossman
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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Strategic Applications of Named Reactions in Organic Synthesis
Modern Physical Organic Chemistry
Advanced Organic Chemistry: Part A: Structure and Mechanisms (Advanced Organic Chemistry / Part A: Structure and Mechanisms)
Advanced Organic Chemistry, Fourth Edition - Part B: Reaction and Synthesis (Advanced Organic Chemistry / Advanced Organic Chemistry)
Name Reactions: A Collection of Detailed Reaction Mechanisms

Accessories:

Introduction to Proteomics: Tools for the New Biology
Conditional Mutagenesis: An Approach to Disease Models (Handbook of Experimental Pharmacology)
Transient Receptor Potential (TRP) Channels (Handbook of Experimental Pharmacology)

ASIN: 0387954686

Book Description

Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. The treatment emphasizes unifying principles, showing how common mechanisms link seemingly disparate reactions. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

The author has drawn on his own research and the current literature to ensure that appropriate attention is given to topics across the range of modern organic chemistry. The text is unique in its inclusion of a chapter on reactions mediated or catalyzed by transition metals, an area in which mechanistic understanding is now essential. Relatively new topics such as olefin metathesis and cycloaromatization are covered without giving short shrift to more traditional areas such as carbonyl chemistry. The text assumes a basic knowledge of organic chemistry. It can be used either in a formal course or by students working on their own, and will be particularly useful for graduate students studying for qualifying examinations. It will also be useful to students and researchers in biochemistry, pharmacology, and inorganic chemistry.

"This is an excellent and well-presented work.... The author ... has succeeded well in treating the central ideas of reactivity and selectivity in an integrated whole. The clear style of writing, the well chosen examples, and the ... concise summaries of the main points provided at the end of each chapter should enable the reader to easily consolidate what has been learned.... The book is indeed a little work of art."

-- Jens Hartung, Angewandte Chemie International Edition

"I have taught a one-credit course with this book for three years, and, uniformly, the students have rated this book highly for its clarity and for the scope of the problems. ... This book does an excellent job at its stated goal: 'to teach students to come up with reasonable mechanisms for reactions they have never seen before.'"

-- Amy Howell, Synthesis

"I have just finished my first year of graduate studies in organic chemistry at Duke University. I just wanted to let you know how much your book got me through the past year of course work.... When it came to mechanisms, I found the clarity and thoroughness I needed only in your book. It was impressive how you were able to present so much information in a clear and comprehensive manner yet keep the book so manageable in size. In addition to the text, I also was able to benefit from the problems.... Great practice!! The on-line answers are much better than looking up answers by reference.... I am reading it again this summer in preparation for my preliminary exam next spring."

-- David Gooden

Customer Reviews:

basics for organic chemist.......2007-05-10

This book is excellent for reaction mechanism. This book is helpful for the undergraduate's organic chem 2 and the grad school's reaction mechanism class. I learned how to move the electron in reasonable way. So in one word, this book is awesome book that I ever read for practicing reaction mechanism.

Excellent Book on Mechanisms.......2006-11-04

I bought this book to practice mechanisms because I'll be taking a physical organic class in the spring that uses them heavily. I used this book instead of sitting in on a sophomore organic class, because by job as a TA conflicted.

Anyway, this book is extraordinary. Dr. Grossman has taught me so many things about how to write a correct mechanism and how to recognize a bad mechanism when I see one. The book is written in a very clear and friendly manner and it's really quite hard to put down when you start reading it.

The book also has practice problems and the book's website has the answers, giving even more incentive to practice mechanisms.

Money well spent........2006-03-21

This compact but content-rich book is ideal for students who have completed at least their first year of organic chemistry (some physical chemistry is helpful but not critical) and wish to improve their understanding of the subject. The writing style is generally remarkably clear and readable; the author manages to make an inherently intimidating subject surprisingly easy to approach and understand.

I would recommend it to any student of chemistry, regardless of whether it fits into your scheduled courses.

Orgo Made Easy!.......2005-09-30

This book is a condensed version of my text book. With this book, GOD and "Orgo for dummies", I aced Organic the first time through.

Surprisingly Easy to Read and Understand.......2005-09-04

Being a PhD student in organic chemistry, I have read a lot of chemistry books in my days, and never have I come across a book that's understandable without a teacher's explanation. The numerous examples and pictures makes understanding what the author is writing about a breeze. I would highly suggest this book to anyone who is looking into pursuing a degree in Chemistry. It has already helped me out a great deal and I'm barely half way through!

Greene's Protective Groups in Organic Synthesis

Average customer rating:

glad i bought it
A must have for any synthetic laboratory
must have
Protecting my thesis
The Book Will be Your Bible in Lab

Greene's Protective Groups in Organic Synthesis
Peter G. M. Wuts , and Theodora W. Greene
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

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Similar Items:

March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (March's Advanced Organic Chemistry)
Strategic Applications of Named Reactions in Organic Synthesis
Purification of Laboratory Chemicals, Fifth Edition
Comprehensive Organic Transformations: A Guide to Functional Group Preparations
Name Reactions: A Collection of Detailed Reaction Mechanisms

ASIN: 0471697540

Book Description

The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including...

New protective groups such as the fluorous family and the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines
New techniques for the formation and cleavage of existing protective groups, with examples to illustrate each new technique
Expanded coverage of the unexpected side reactions that occur with protective groups
New chart covering the selective deprotection of silyl ethers
3,100 new references from the professional literature

The content is organized around the functional group to be protected, and ranges from the simplest to the most complex and highly specialized protective groups.

Customer Reviews:

glad i bought it.......2007-08-31

i'm do organic synthesis. i reference this one once a week on average. it's the first stop whenever a protecting group questions comes up.

A must have for any synthetic laboratory.......2006-04-27

There are other protecting group books out there but I found this one to be the most comprehensive and easy to use.

must have.......2006-02-24

if you are synthetic chemist you ought to have this book with you

Protecting my thesis.......2004-08-15

This book contains methods for the installation and removal of practically every protecting group you can think of, and likely some you've never encountered. Most methods are referenced to articles containing representative procedures, saving valuable time scouring the literature. It is compact, well-organized and reasonably priced. Along with March's Advanced Organic Chemistry, this book is a must have for any organic chemist.

The Book Will be Your Bible in Lab.......2002-02-04

If you doing any sort of organic chemistry in the lab, you will really get your hands into this handy reference on protecting groups. The book neatly organized into functional groups and their protecting groups. A Primer for organic chemists. It will save you zillion hours of researching for papers/references on the appropriate protecting groups used in reactions.

Synthesis and Applications of Isotopically Labelled Compounds, Volume 7

Average customer rating:

Synthesis and Applications of Isotopically Labelled Compounds, Volume 7

Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Hardcover

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Book Description

This outstanding book covers the most recent advances in the production of stable and radioactive isotopes as well as in the synthesis, analysis and applications of isotopically labelled compounds. Written by internationally renowned contributors, it provides authoritative and wide-ranging coverage of significant growth areas including:

new methodologies in the production of isotopes
novel approaches to compounds labelled with isotopes of hydrogen, carbon and other stable, long-lived and short-lived radioactive isotopes
advances in the analysis of istopically labelled compounds
recent and future applications of isotopes in pharmaceutical research and development, in pharmacological and clinical sutdies and nuclear medicine, as well as in agricultural, nutritional and environmental research
recent applications of isotopes in investigating organic and bioorganic mechanisms and pathways
safety and regulations of handling isotopes

This will be an invaluable information and reference source to anyone involved in the production of isotopes, the synthesis and analysis of compounds labelled with stable, long-lived or short-lived radioactive isotopes, in drug research and development, in clinical investigations and nuclear medicine, in agricultural research and development and environmental investigations, in the elucidation of biological and chemical pathways, handling radioisotopes, laboratory design and other areas.

Heterogeneous Catalysis in Organic Chemistry

Average customer rating:

Heterogeneous Hydrogenation Made Accesible

Heterogeneous Catalysis in Organic Chemistry
Gerard V. Smith , and Ferenc Notheisz
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0126516456

Book Description

The features of this book which will be of special interest to academic organic chemists are the introduction (Chapter 1), which presents a short course on the concepts and language of heterogeneous catalysis, covers organic reaction mechanisms of hydrogenation (Chapter 2), hydrogenolysis (Chapter 4), and oxidation (Chapter 6), a presents problems and solutions specific for running heterogeneous catalytic organic reactions in solution. These materials can supplement advanced chemistry courses.

Most synthetic organic chemists use a variety of "protecting groups" which they attach to functional groups (reactive groups of atoms) while some reaction is being conducted on another part of the molecule. These protecting groups prevent reactions of the functional groups during other reactions and are removed later by a heterogeneous catalytic method called hydrogenolysis. One unique feature of this book, not found in other books on catalysis, is an exhaustive chapter (Chapter 4) on hydrogenolysis, which is dredged from the recent synthetic literature published by modern organic chemists. Academic organic chemists should find this chapter extremely useful and may wish to adopt the book as a supplement for advanced organic chemistry courses designed for seniors and for graduate students. It will also be useful for professors and their research groups engaged in synthetic organic chemistry.

Many academic organic chemists are not aware of recent advances in heterogeneous enantioselective catalysis (Chapter 3) or in selective low temperature, liquid phase heterogeneous catalytic oxidations by hydrogen peroxide (Chapter 6). These specialty topics are timely and may be new to academic organic chemists and can be used to supplement their advanced courses.

Several features of this book will also be of special interest to industrial chemists who are unfamiliar with heterogeneous catalysis. Many good organic chemists are hire by industry. They synthesize a new compound using standard organic synthetic techniques but are informed by their supervisor that they must convert some of their synthetic steps into heterogeneous catalytic steps. They may not have been exposed to heterogeneous catalysis and have few places to turn. This book offers them a crash course in heterogeneous catalysis as well as many examples of reactions and conditions with which they can start their search.

Those industrial organic chemists already familiar with heterogeneous catalysis will find this book useful as a reference to many examples in the recent literature. They will find recent surface science discoveries correlated with heterogeneous catalysis or organic reactions and mechanistic suggestions designed to stimulate innovative nontraditional thinking about organic reactions on surfaces.

Key Features
* Written by organic chemists for organic chemists
* Introduces heterogeneous catalysis concepts and language
* Presents a comprehensive compilation of protecting group removal procedures
* Covers liquid-phase hydrogenations, hydrogenolysis, and oxidations
* Addresses heterogeneous methods for producing pure enantiomers of chiral products
* Examines the emerging field of heterogenized homogeneous catalysts
* Mixes practical applications with mechanistic interpretations

Customer Reviews:

Heterogeneous Hydrogenation Made Accesible.......2000-04-08

For the advanced organic chemistry researcher who is entering the wonderful world of heterogeneous catalysis in general - and heterogeneous hydrogenation in particular - there is no single resource such as this to guide him. Working in the field of heterogeneous hydrogenation myself, I had felt that a modern, up-to-date, readable text was long overdue. Heterogeneous Catalysis in Organic Chemistry has all of these attributes and much much more. It will help you o brave chemist to safely navigate the enormous and often useless primary literature and reach what you were looking for. Be that experimental details for a particular transformation, current developments in the scope of the field, understanding of the underlying theory. I strongly reccomend all organic synthesis research departments obtain a copy. It will be invaluable for the whole range of staff, from the first year inexperienced graduate student nervously exploring the field, to the research group leader who wants to update his knowledge and understanding, painlesly, accurately and quickly.

Average customer rating:

Highly Recommended
A Great Read and a Great Book
Organic Chemists and Students Must Have!

Advanced Practical Organic Chemistry
J. Leonard , B. Lygo , and G. Procter
Manufacturer: CRC
ProductGroup: Book
Binding: Paperback

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Similar Items:

Vogel's Textbook of Practical Organic Chemistry (5th Edition)
March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (March's Advanced Organic Chemistry)
The Art of Writing Reasonable Organic Reaction Mechanisms
Advanced Organic Chemistry: Part A: Structure and Mechanisms (Advanced Organic Chemistry / Part A: Structure and Mechanisms)
Greene's Protective Groups in Organic Synthesis

ASIN: 0748740716

Book Description

The first edition of this book achieved considerable success due to its ease of use and practical approach, and to the clear writing style of the authors. The preparation of organic compounds is still central to many disciplines, from the most applied to the highly academic and, more tan ever is not limited to chemists. With an emphasis on the most up-to-date techniques commonly used in organic syntheses, this book draws on the extensive experience of the authors and their association with some of the world's mleading laboratories of synthetic organic chemistry. In this new edition, all the figures have been re-drawn to bring them up to the highest possible standard, and the text has been revised to bring it up to date. Written primarily for postgraduate, advanced undergraduate and industrial organic chemists, particularly those involved in pharmaceutical, agrochemical and other areas of fine chemical research, the book is also a source of reference for biochemists, biologists, genetic engineers, material scientists and polymer researchers.

Customer Reviews:

Highly Recommended.......2007-10-01

As a physical chemist/spectroscopist by training who suddenly found myself needing to synthesize & characterize some model compounds for my experiments, I found this book to be a very helpful review of modern synthetic techniques, particularly in regards to purifying starting materials, dealing with air-sensitive compounds, and monitoring the reaction's progress. Definitely a recommended reference for any chemist. It's companion, "Advanced Practical Inorganic and Metalorganic Chemistry", is also highly recommended, though if I had to choose between the two I'd say that "Advanced Practical Organic Chemistry" is most useful.

A Great Read and a Great Book.......2007-04-05

A wonderful book. Whether you're in need of a nomograph, quick info on your solvents/reagents(as well as some common procedures for certain reagents), or if you're about a senior-undergrad/1st-2nd year grad student working in an organic lab and need a little refresher crash course, this book has it all(in a general sense). Contains a brief, but concise, walkthrough of considerations before starting a desired reaction all the way through the work-up and purification(very, very nice). As the previous reviewer said, and I agree completely, this book is a must-have for any organic chemist.

Organic Chemists and Students Must Have!.......2001-08-06

The book discusses fundamental techniques in organic laboratory. Topics that I found very useful are running the reaction (i.e. air-sensitive and water-sensitive chemistry), monitoring reaction (i.e.thin-layer chromatography), working up reaction (have you wondered why ammonium chloride is a good reagent to work up the reaction? how to efficiently separate layers without emulsions?, etc), purifying compounds (i.e. distillation, recrystallization, determining the sizes of columns, choice of eluting solvents,...) The book should be on the shelf of every chemist.

Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition, Second Edition

Average customer rating:

A lot of problems will be solved in later revisions
Professor Silverman does it again!

Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition, Second Edition
Richard B. Silverman
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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Similar Items:

Modern Physical Organic Chemistry
The Organic Chemistry of Biological Pathways
The Organic Chemistry of Drug Design and Drug Action, Second Edition
Medicinal Natural Products: A Biosynthetic Approach
Modern Methods of Organic Synthesis (4th Edition)

ASIN: 0126437319

Book Description

The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed.

This is a revised edition of a very successful book, which appeals to both academic and industrial markets.

Illustrates the organic mechanism associated with each enzyme-catalyzed reaction
Makes the connection between organic reaction mechanisms and enzyme mechanisms
Compiles the latest information about molecular mechanisms of enzyme reactions
Accompanied by clearly drawn structures, schemes, and figures
Includes an extensive bibliography on enzyme mechanisms covering the last 30 years
Explains how enzymes can accelerate the rates of chemical reactions with high specificity
Provides approaches to the design of inhibitors of enzyme-catalyzed reactions
Categorizes the cofactors that are appropriate for catalyzing different classes of reactions
Shows how chemical enzyme models are used for mechanistic studies
Describes catalytic antibody design and mechanism
Includes problem sets and solutions for each chapter
Written in an informal and didactic style

Customer Reviews:

A lot of problems will be solved in later revisions.......2003-05-05

The index for this book .... For example, there are a fair number of examples of the epoxidation reaction, but not a single pointer toward that in the index of the book. And much the same thing for other types of reactions.

It would also be nice if there was a more clear transfer between basic organic principles and then biological applications.

He does do a good job showing this is some cases (i.e., the benzoin condensation), but a few more parallel examples would have been very useful.

Professor Silverman does it again!.......2000-06-17

This book is an excellent resource for undergraduate and graduate students studying enzyme chemistry and organic mechanisms. Prof. Silverman does a fine job of giving many different examples of enzyme mechanisms. By not focusing totally on one kind of enzyme or catalysis, he succeeds in painting a broad picture for the reader, while not sacrificing content. The only drawback to this edition is the large amount of typographical errors that appear throughout. Perhaps better editing is in order for future editions.

Strategies and Tactics in Organic Synthesis, Volume 2: Volume 2 (Strategies and Tactics in Organic Synthesis)

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Strategies and Tactics in Organic Synthesis, Volume 2: Volume 2 (Strategies and Tactics in Organic Synthesis)

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0124502814

Book Description

This is a unique account of the synthesis of organic molecules. All of the contributors are acknowledged experts in organic synthesis.

Strategic Applications of Named Reactions in Organic Synthesis: Premium Hardcover Edition with CD-ROM : Background and Detailed Mechanisms

Average customer rating:

Strategic Applications of Named Reactions in Organic Synthesis: Premium Hardcover Edition with CD-ROM : Background and Detailed Mechanisms
Laszlo Kurti , and Barbara Czako
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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Similar Items:

Greene's Protective Groups in Organic Synthesis
Modern Physical Organic Chemistry
March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (March's Advanced Organic Chemistry)
The Art of Writing Reasonable Organic Reaction Mechanisms
Comprehensive Organic Transformations: A Guide to Functional Group Preparations

ASIN: 0123694833

Book Description

Kurti and Czako's Strategic Applications of Named Reactions in Organic Synthesis: Premium Hardcover Edition with CD-ROM is an indispensable tool for both specialists and non-specialists in the field of organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient two-page layout, using color for the first time in an advanced-level organic chemistry book. Each reaction includes a list of main features, a general scheme of the transformation, and a detailed arrow-pushing mechanism based on the latest experimental evidence. It then provides numerous examples demonstrating the synthetic utility of each reaction followed by a list of references.

This premium hardback edition also includes a CD-ROM that integrates a PDF master page linked via color links to the text pages of the book itself. A user will be able to go from lecture format to the bookpage and back with the click of a mouse.

Together both the CD-ROM and hardback text offers the most comprehensive coverage, superb organization, quality of presentation, and wealth of references for organic chemists everywhere.Due to its comprehensive coverage, superb organization, quality of presentation, and wealth of references, this long-awaited book belongs on the shelf of every organic chemist.

* The first reference work on named reactions to present colored schemes for easier understanding
* 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples
* An opening list of abbreviations includes both structures and chemical names
* Contains more than 10,000 references grouped by seminal paper, reviews, modifications, and theoretical works
* Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools
* Extensive index quickly locates information using words found in text and drawings

Average customer rating:

Organic Reactions
Inc. Organic Reactions
Manufacturer: Wiley
ProductGroup: Book
Binding: Hardcover

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Organic Reactions (Volume 48)

ASIN: 0471682586

Book Description

Organic Reactions is a comprehensive series of volumes composed of chapters devoted to important synthetic reactions. For each volume, the chapter authors are world-renowned experts with extensive hands-on experience in the field. The chemistry is presented from a preparative point of view and particular attention is given to reaction limitations, interfering influences, effects of chemical structure, and the selection of experimental conditions.
* Each reaction is fully referenced to the primary literature
* Numerous detailed procedures illustrate the significant modifications of each method
* Includes tables that contain all possible examples of the reaction under consideration

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