Protein NMR Spectroscopy: Principles and Practice

Book Description

Protein NMR Spectroscopy combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical models and experimental techniques, Protein NMR Spectroscopy develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.

Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. The second edition includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.

Protein NMR Spectroscopy is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or who wish to understand the latest developments in this field.

· Provides an understanding of the theoretical principles important for biological NMR spectroscopy
· Demonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experiments
· Allows for the capability of designing effective experimental protocols for investigations of protein structures and dynamics
· Includes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods

Customer Reviews:

Satisfied.......2007-09-05

I have been reading this book for a while and decided to buy it. I am satisfied with the vendor, it arrived in good condition and fairly on time.

New 'Bible' for Protein NMR.......2007-06-16

This is the new standard for Protein NMR spectroscopists (the old one being Ernst). Everyone I've met who uses NMR in biology has nothing but praise for this book. It's not a perfect book and has some weakness, especially in the modelling portions. The math derivations are clear but the authors do not connect back to the physical phenomenon. I would recommend keeping a QM book nearby as a reference. However, this book is well written overall and very complete. Highly recommended!

Useful Handbook for Protein NMR study.......2000-04-29

The book is very complete, covers most of the field in protein NMR studies. The book is well organised, with plenty of figures to facilitate easy understanding of the subject. Overall, I find it is very helpful for anyone who will be interested in protein NMR research. I have actually seen quite a number of copies in a few NMR laboratories and I would recommand this book to all those who are looking for an complete introductory book in NMR and protein study.

Introduction to Chemical Principles: A Laboratory Approach (Brooks/Cole Laboratory Series for Introductory Chemistry)

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Introduction to Chemical Principles: A Laboratory Approach (Brooks/Cole Laboratory Series for Introductory Chemistry)
Susan A. Weiner
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Paperback

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Introduction to Chemical Principles (9th Edition)
Introductory Chemistry Essentials and CW Access Card Package (2nd Edition)
Introductory Chemistry Solutions Guide
Solutions Guide Introductory Chemistry: A Foundation/Introductory Chemistry/Basic Chemistry
Foundations of College Chemistry

ASIN: 0534407773

Book Description

Don't go to the lab without it! INTRODUCTORY TO CHEMICAL PRINCIPLES: A LABORATORY APPROACH teaches you to collect and analyze experimental data with ease using 34 class-tested experiments. Work Pages and Report Sheets for each experiment offer a convenient and efficient way for you to record your data as you work. Advanced Study Assignments, Sample Calculations, and laboratory and safety procedures are just a few of the tools that will help you complete your lab experiments successfully.

Chemical Principles in the Laboratory (Brooks/Cole Laboratory Series for General Chemistry)

Average customer rating:

Good introductory chemistry lab book

Chemical Principles in the Laboratory (Brooks/Cole Laboratory Series for General Chemistry)
Emil Slowinski , Wayne C. Wolsey , and William L. Masterton
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Spiral-bound

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Chemistry: Principles and Reactions (with CD-ROM and InfoTrac®)
General Chemistry
Chemistry
Chemistry, Fourth Edition
Chemistry (5th Edition) (MasteringChemistry Series)

ASIN: 0534424538

Book Description

Succeed in chemistry with CHEMICAL PRINCIPLES IN THE LABORATORY! Clear, user-friendly, and direct, this lab manual provides you with the tools you need to successfully complete lab experiments and lab reports. Analyzing the data you observe in the lab sessions is easy with the Advance Study Assignments, found throughout the manual, that give you extra practice with processing data through sample questions.

Customer Reviews:

Good introductory chemistry lab book.......2000-02-26

This book uses removable pages as prelabs which were very good in giving a conceptual idea of the experiments before they were done. Also, there are good flowcharts, equations for every step of the reactions, and formulas to help do the problems. All data that needs to be recorded is clearly mentioned in a form format.

Principles of Instrumental Analysis (Saunders Golden Sunburst Series)

Average customer rating:

Not so good
Instrumental text book review
alternatives to this book
So disorganized a book that it hurts
Style of writing is painful

Principles of Instrumental Analysis (Saunders Golden Sunburst Series)
Douglas A. Skoog , F. James Holler , and Timothy A. Nieman
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Hardcover

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Inorganic Chemistry
Lehninger Principles of Biochemistry, Fourth Edition
Inorganic Chemistry (2nd Edition)
Physical Chemistry
Experiments In Physical Chemistry

ASIN: 0030020786

Book Description

This text is written for a course that deals with the principles and applications of modern analytical instruments. Emphasis is placed upon the theoretical basis of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations. The text also introduces students to elementary integrated circuitry, microprocessors and computers, and treatment of analytical data.

Customer Reviews:

Not so good.......2007-09-18

I have to use this textbook for one of my classes, and I must say, it is horrible. The examples for problems in the book hardly give any explanation of what they are doing. The questions at the end of the chapter are very difficult and looking back at the chapter just makes the question even more confusing. I like to use textbooks when I do not understand what is going on in my class, but this one does not help at all! I think the only way you can understand this book is if you are already well educated in the course. Everytime I am assigned problems in the book, I cringe, because I know I am going to be spending hours being more confused than I have ever been in my life.

Instrumental text book review.......2007-07-20

This book covers the basics of instrumental analysis well. This is not a book for someone who needs colored illustrations and flashy pictures. The key words do not jump out of the page like many of the new undergraduate text books. The text is to the point. As with any textbook, there are some minor errors, but this book is better than some others I've encountered.

alternatives to this book.......2007-03-09

I'm not sure why there are so many negative reviews of this book. I found it to be very solid.

For those of you who don't like it you have 3 options:

either "Instrumental Methods of Analysis" by Willard, Merritt, Dean, Settle; (ISBN 0534081428) which is excellent and a true classic.

or "Chemical Analysis: Modern Instrumentation Methods and Techniques" by Francis Rouessac & Annick Rouessac

or "Chemical Instrumentation: A Systematic Approach" by Strobel and Heineman. This book, however, is very hardware oriented and not a general instrumental analysis text.

I would also recommend that you buy "Statistics and Chemometrics for Analytical Chemistry" by James N. Miller & Jane C. Miller. It does a much better job than the cursory chapters found in regular analytical texts. Get the 4th or 5th edition. For a paperback, this book is ridiculously expensive if you buy new. Try to find a used copy.

While the book by Miller & Miller is good, it's no substitute for a 1 or 2 semester course in stats. A good book for this material might be Statistics for Research, Third Edition by Shirley Dowdy, Stanley Wearden, Daniel Chilko (ISBN 047126735X)

Check out my other reviews for other undergrad. chem books.

So disorganized a book that it hurts.......2005-12-24

There is no clear organization in this book. Seems like they took many papers and at random picked paragraphs out of them. The only place they show organization is when they are introducing stuff in a chapter.
Works as a reference book because you can look in the back and find the 6 or seven places your topic of interest is scattered in the book. but in general the gain of knowledge through the organization of this book is near to impossible.
The authors of this book should be ashamed of themselves for doing such harm to Chemistry students.

Style of writing is painful.......2005-09-02

Just start reading the introduction, or flip to anywhere in this book to see all you need to know about it's readability: a bit rough to say the least.

For example, in the introduction, the concept of carrying binary data in a shorter period of time on a wire than several measured pulses was presented in such a confusing manner that I was forced to read it 4 times to understand what was already a simple and understood concept to me. The excessive formality of this book is a killer.. It reads at times like a formal mathematics proof book, however, at other times it is a bit more readable.

Like people said.. use this for reference.. not for a textbook.

Laboratory Manual for Principles of General Chemistry

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Lab manual for Prin. of Gen. Chem.
Opinion

Laboratory Manual for Principles of General Chemistry
Jo Allan Beran
Manufacturer: Wiley
ProductGroup: Book
Binding: Paperback

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Chemistry and Chemical Reactivity (with General ChemistryNOW CD-ROM)
General Chemistry
Chemistry and Chemical Reactivity, Volume 1 (with General ChemistryNOW)
General Chemistry
Student Solutions Manual for Kotz/Treichel/Weaver's Chemistry and Chemical Reactivity, 6th

Accessories:

General Chemistry I as a Second Language: Mastering the Fundamental Skills

ASIN: 0471214981

Book Description

This remarkably popular lab manual has won over users time and time again with its exceedingly clear presentation and broad selection of topics and experiments. Now revised and fine-tuned, this new Seventh Edition features three new experiments: Water Analysis: Solids (Experiment 3); Vitamin C Analysis (Experiment 16); and Hard Water Analysis (Experiment 30). In addition, nearly 900f the Prelaboratory Assignment Questions and Laboratory Questions are either new or revised.

Customer Reviews:

Lab manual for Prin. of Gen. Chem........2007-09-19

This lab manual is the one required for my chemistry lab class at a much better price than the school offered.

Opinion.......2007-04-25

It is a typical boring and verbose, but yet comlete and unclear, lab instructions. You wont have a choice so just buy it.

Biological Safety: Principles and Practices (Biological Safety: Principles & Practices)

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Biological Safety: Principles and Practices (Biological Safety: Principles & Practices)

Manufacturer: American Society Microbiology
ProductGroup: Book
Binding: Hardcover

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Disinfection, Sterilization, and Preservation (Disinfection, Serilization & P)
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Control Of Communicable Diseases Manual (Control of Communicable Diseases Manual) (Control of Communicable Diseases Manual)

ASIN: 1555811809

Book Description

Written by recognized authorities with decades of experience in the biological safety field, the third edition of this best-selling volume is an essential resource as well as an excellent text for courses in biosafety. The epidemiology of laboratory-associated infections, including some previously unreported cases, is thoroughly covered. Detailed chapters cover hazard assessments of the wide range of pathogens and biological toxins encountered in biomedical laboratories as well as other occupational settings. All facets of hazard control, from personal protective equipment to institution-wide provisions and policies, are discussed.

Solid-Phase Extraction: Principles, Techniques, and Applications

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Solid-Phase Extraction: Principles, Techniques, and Applications
Nigel J.K. Simpson
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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Solid-Phase Extraction: Principles and Practice
The HPLC Solvent Guide

ASIN: 082470021X

Book Description

Demonstrating the relationship of the basic theory of solid-phase extraction (SPE) to chromatography, this comprehensive reference illustrates how SPE techniques significantly contribute to the preparation of samples for a wide variety of analytical techniques. It provides step-by-step details on the applications of SPE to environmental matrices, broad-spectrum drug screening, veterinary drug abuse, pharmaceutical drug development, biological samples, and high-throughput screening. Written by world-renowned experts in the field, the book contains helpful reference charts, tables of solvent properties, selectivities, molecular acid/base properties, and more.

Chemical Principles in the Laboratory: With Qualitative Analysis : Alternate Version

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Chemical Principles in the Laboratory: With Qualitative Analysis : Alternate Version
Emil J. Slowinski , Wayne C. Wolsey , and William L. Masterton
Manufacturer: Harcourt Brace College Publishers
ProductGroup: Book
Binding: Paperback

General & Reference | Chemistry | Science | Subjects | Books

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Chemistry

ASIN: 003019234X

BioNMR in Drug Research (Methods and Principles in Medicinal Chemistry, V. 16)

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BioNMR in Drug Research (Methods and Principles in Medicinal Chemistry, V. 16)

Manufacturer: Wiley-VCH
ProductGroup: Book
Binding: Hardcover

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ASIN: 3527304657

Book Description

The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt W?h. Edited by a former coworker of W?h, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids.

BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein. Its use thereby benefits the rational development of drugs. This interaction can now be investigated in a hitherto unparalleled precision and displayed in 3D—an important prerequisite for the targeted development of new active substances. The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical research. Thus it comes as no surprise that a large number of the authors are working for leading pharmaceutical companies.

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