Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding

Customer Reviews:

A lot of information, but not-so-well explained..........2005-04-13

With an undergrad degree in chemistry and a year of graduate school (granted, without a focus solely in biochemistry), this text was often difficult for me to follow and gain much from. Though the text contained an impressive breadth of topics, this breadth came at the cost of depth. In my opinion, a textbook should more-or-less stand on its own in providing a clear understanding of a topic. All too often I didn't find this to be the case with the Fersht book. Instead, I often had to consult many of the references listed in the text to obtain sufficient understanding of topics. (Fortunately, the book includes extensive reference lists.) If looking up endless references (many old and sometimes difficult to obtain) is something you enjoy, this book is for you.--If not, forget it!

Highly recommend it.......2003-08-31

Hands down the bible of enzyme kinetics!

Anyone looking to learn more about enzyme kinetics, thermodynamics, structure, and function will find this book clear, thoughtfully written, and at the forefront in the field.

essential.......2002-05-01

If you are studying protein structure, you probably should read this book for reference.

This is solely my opinion, but I have learned new things and reinforced some old knowledge, as well. The book is well-written, and understandable, without being simplistic.

Some texts are difficult to understand, or dry, or facile. This is not one of those texts.

Biochemists Can't Miss.......2001-08-23

The book focuses on enzyme catalysis, stereochemistry of enzyme reactions, determination of rate constant, enzyme kinetics, and protein structure and folding. It would be an ideal reference for the study of protein chemistry. It can serve as the primary text for an advanced course in protein chemistry or a supplement for undergraduate biochemistry text.

Protein folding has remained one of the most intricate yet less understood process in modern biochemistry. Feersht's treatise of the subject in this book is splendid. The author overviews protein structure and diversity in the opening chapter. What I find really precious about this book is the discussion on protein engineering, forces on folding, and recombinant DNA technology in the context of protein folding.

Aside from protein chemistry, the chapter on chemical catalysis is excellent in learning more about transition state theory, general acid/base catalysis, covalent catalysis, structure-reactivity relationships, and kinetic isotope effects.

The Mother of All Enzyme Books.......2001-01-10

Man, this book rocked! I took one look at the ribbon structure of ATPase on the cover and said to myself, "Whoa dude! This is, like, phat!" Then I turned the pages and BAM! I was knee deep in protein structure! Like, any first-year biochemist knows its all about the acids, as in amino, and Fersht, he knows his peptides! Oh man, I was on cloud nine! And I've been off my meds for two months now! But you wanna know the real dope? You can't say diddly about function unless you know structure, and that Alan, as in Fersht, dude! Like, he starts you off simple, like, you know, with the "building blocks," like we're a bunch of two-year-olds, and you string 'em together and get all that higher-order structure and stuff, and slowly, ever so slowly, like a mental itch that invades your consciousness and becomes screaming voices telling you to AHHHHHHHHH! So many domains! Too many functional units! No, no, nooooooo! Schiff base? Shift Bass! Ah HA HA HA HA! What do all those K's mean!?! Take me home! Please...

Homogeneous Catalysis: Mechanisms and Industrial Applications

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Homogeneous Catalysis: Mechanisms and Industrial Applications
Sumit Bhaduri , and Doble Mukesh
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471372218

Book Description

Homogeneous catalysis made easy through real-world examples and illustrations.

The field of homogeneous catalysis has grown dramatically over the past decade, boasting many new applications in the chemical, fine chemical, and pharmaceutical industries. This timely work offers a unified, easy-to-understand treatment of this challenging area of chemistry. With a practical emphasis and a thorough, selective survey of current literature, the authors present homogeneous catalytic reactions proven successful in industrial applications-illustrating both the mechanistic principles and illuminating new areas of academic and industrial research. An ideal self-study guide for inorganic chemists seeking to gain entry into the field as well as a much-needed reference for industry professionals, Homogeneous Catalysis: Mechanisms and Industrial Applications features:

Clear discussions of the fundamental chemical and chemical engineering concepts relevant to homogeneous catalysis.

Important examples from selected industrial processes.

Extensive references to cutting-edge research with application potential (through March of 1999).

Many tables and more than 100 illustrations to help explain difficult concepts.

Problems of variable complexities accompanying each chapter.

Average customer rating:

Good Book for Advanced Reaction Theory
Great content, but hampered by mistakes

Chemical Kinetics & Catalysis
Richard I. Masel
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

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An Introduction to Statistical Thermodynamics

ASIN: 0471241970

Book Description

Chemical Kinetics and Catalysis is a comprehensive guide to chemical kinetics and catalysis, and focuses on the use of computational tools for studying chemical kinetics and catalytic phenomena. Provides a thorough and up-to-date treatment of chemical kinetics and catalysis, combining traditional background information with the latest computational methods for fitting data to appropriate rate equations. Demonstrates how the vastly improved computational tools now available allow application of kinetic concepts to understanding and predicting the behavior of diverse and complex phenomena, including biological systems, semiconductor growth, and corrosion.

Contains chapters reviewing of kinetic concepts, introducing kinetics via rate equations and mechanisms, explaining the theory of reaction rates (a section on trajectory calculations to simulate reactions), predicting potential energy surfaces (methods for directing the reaction rate), and discussing catalysis with a focus on modifying the reaction rate.
A useful reference guide, providing the essential basics along with numerous solved examples, problems, and illustrative computer programs.

Customer Reviews:

Good Book for Advanced Reaction Theory.......2002-07-12

This book does a good job of explaining the basis for reaction mechanisms and how catalysts work. The technical level of this book requires students to have at least a couple of advanced chemistry classes, such as physical chemistry, in their background. In summary, buy this book if you are looking to expand your understanding of chemical reactions and have a solid understanding of the basic chemistry principles.

Great content, but hampered by mistakes.......2002-03-13

Good book for undergrad and grad students who've already had reactor design and p.chem. Much of the theory, in latter half of the book, takes basis from statistical thermo, so p.chem may be useful. As a student w/o such bkgds, overall I find the book to be very clear in explanation. Delivery of material is deliberate and well thought out. Appreciate the use of many example problems. Unfortunately, no solutions for the Problems at end of chapter.

Unfortunately, the book has a ton of mistakes, some simply typos, but some are very critical mistakes in example problems, some of which are very subtle.

Book Description

The features of this book which will be of special interest to academic organic chemists are the introduction (Chapter 1), which presents a short course on the concepts and language of heterogeneous catalysis, covers organic reaction mechanisms of hydrogenation (Chapter 2), hydrogenolysis (Chapter 4), and oxidation (Chapter 6), a presents problems and solutions specific for running heterogeneous catalytic organic reactions in solution. These materials can supplement advanced chemistry courses.

Most synthetic organic chemists use a variety of "protecting groups" which they attach to functional groups (reactive groups of atoms) while some reaction is being conducted on another part of the molecule. These protecting groups prevent reactions of the functional groups during other reactions and are removed later by a heterogeneous catalytic method called hydrogenolysis. One unique feature of this book, not found in other books on catalysis, is an exhaustive chapter (Chapter 4) on hydrogenolysis, which is dredged from the recent synthetic literature published by modern organic chemists. Academic organic chemists should find this chapter extremely useful and may wish to adopt the book as a supplement for advanced organic chemistry courses designed for seniors and for graduate students. It will also be useful for professors and their research groups engaged in synthetic organic chemistry.

Many academic organic chemists are not aware of recent advances in heterogeneous enantioselective catalysis (Chapter 3) or in selective low temperature, liquid phase heterogeneous catalytic oxidations by hydrogen peroxide (Chapter 6). These specialty topics are timely and may be new to academic organic chemists and can be used to supplement their advanced courses.

Several features of this book will also be of special interest to industrial chemists who are unfamiliar with heterogeneous catalysis. Many good organic chemists are hire by industry. They synthesize a new compound using standard organic synthetic techniques but are informed by their supervisor that they must convert some of their synthetic steps into heterogeneous catalytic steps. They may not have been exposed to heterogeneous catalysis and have few places to turn. This book offers them a crash course in heterogeneous catalysis as well as many examples of reactions and conditions with which they can start their search.

Those industrial organic chemists already familiar with heterogeneous catalysis will find this book useful as a reference to many examples in the recent literature. They will find recent surface science discoveries correlated with heterogeneous catalysis or organic reactions and mechanistic suggestions designed to stimulate innovative nontraditional thinking about organic reactions on surfaces.

Key Features
* Written by organic chemists for organic chemists
* Introduces heterogeneous catalysis concepts and language
* Presents a comprehensive compilation of protecting group removal procedures
* Covers liquid-phase hydrogenations, hydrogenolysis, and oxidations
* Addresses heterogeneous methods for producing pure enantiomers of chiral products
* Examines the emerging field of heterogenized homogeneous catalysts
* Mixes practical applications with mechanistic interpretations

Customer Reviews:

Heterogeneous Hydrogenation Made Accesible.......2000-04-08

For the advanced organic chemistry researcher who is entering the wonderful world of heterogeneous catalysis in general - and heterogeneous hydrogenation in particular - there is no single resource such as this to guide him. Working in the field of heterogeneous hydrogenation myself, I had felt that a modern, up-to-date, readable text was long overdue. Heterogeneous Catalysis in Organic Chemistry has all of these attributes and much much more. It will help you o brave chemist to safely navigate the enormous and often useless primary literature and reach what you were looking for. Be that experimental details for a particular transformation, current developments in the scope of the field, understanding of the underlying theory. I strongly reccomend all organic synthesis research departments obtain a copy. It will be invaluable for the whole range of staff, from the first year inexperienced graduate student nervously exploring the field, to the research group leader who wants to update his knowledge and understanding, painlesly, accurately and quickly.

Fischer-Tropsch Technology (Studies in Surface Science and Catalysis)

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Fischer-Tropsch Technology

Fischer-Tropsch Technology (Studies in Surface Science and Catalysis)

Manufacturer: Elsevier Science
ProductGroup: Book
Binding: Hardcover

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ASIN: 044451354X

Book Description

Fischer-Tropsch Technology is a unique book for its state-of-the-art approach to Fischer Tropsch (FT) technology. This book provides an explanation of the basic principles and terminology that are required to understand the application of FT technology. It also contains comprehensive references to patents and previous publications. As the first publication to focus on theory and application, it is a contemporary reference source for students studying chemistry and chemical engineering. Researchers and engineers active in the development of FT technology will also find this book an invaluable source of information.

* Is the first publication to cover the theory and application for modern Fischer Tropsch technology
* Contains comprehensive knowledge on all aspects relevant to the application of Fischer Tropsch technology
* No other publication looks at past, present and future applications

Customer Reviews:

Fischer-Tropsch Technology.......2007-01-09

This is a very complete and up-to-date review of the topic. It is written by two people who are intimately involved with the latest research and commercial developments in this area. All aspects of Fischer-Tropsch technology are covered in great detail along with the complementary technologies such as gasification. An excellent set of references is supplied. Historically relevant work is also covered. The only negative comment I can make is a minor one; the English is not always grammatically correct and I would suggest some punctuation changes. However, this does not affect the clarity of the presentation.

Physical Chemistry of Surfaces, 6th Edition

Average customer rating:

Great book for reference
Excellent overview or starting point
Physical Chemistry of Surfaces
The new edition is a lot worse than the earlier editions
To many references

Physical Chemistry of Surfaces, 6th Edition
Arthur W. Adamson , and Alice P. Gast
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471148733

Book Description

"Should be on every surface chemist's reading list." -Spectroscopy (on the Fifth Edition)

Bridging the methodologies of "wet" and "dry" surface chemistry to present surface chemistry as a single broad field, Physical Chemistry of Surfaces, Sixth Edition retains its position as the standard work of surface science. This heavily revised and updated edition provides thorough coverage for students and professionals. New features of the Sixth Edition include:
* Expanded treatment of films at the liquid-air and liquid-solid interfaces, with contemporary techniques and macromolecular films
* Techniques for tunneling and atomic force scanning microscopes
* In-depth coverage of heterogeneous catalysis, including the case of CO on metals
* Increased emphasis on the flexible surface and restructuring of surfaces when adsorption occurs
* A new chapter on macromolecular films

The book begins with the basics of the physical chemistry of liquid-gas and liquid-solid interfaces, including electro-chemistry, long-range forces, and the various methods of spectroscopic and structural study of surfaces. These are followed by descriptive treatments of topics such as friction, lubrication, adhesion and emulsion, foams, and aerosols. Closing chapters present a quantitative approach to physical and chemical adsorption of vapors and gases as well as heterogeneous catalysis.

For senior-level undergraduates and graduate students, each chapter presents the basic surface chemistry of the topics with full derivations, end-of-chapter problems, and reviews of recent advances. This book is also an excellent reference for professional chemists interested in applying surface chemistry to their work.

Customer Reviews:

Great book for reference.......2006-08-03

I had this book as my textbook for my "surface science" class. It is a great book for reference though it does take time and effort to comb through chapters to find what you need. A lot of detailed paper-review-style chaptors which is great for research while it is a little bit overwhelming to people without any physical chemistry background.

Excellent overview or starting point.......2004-06-17

How useful and valuable this book is largely depends on what you expect from it. This book provies an overview of the extremely broad field of surface chemistry. As a starting point to learning about that field, this book is excellent. There is validity to the criticisms offered by some other reviewers of this text. The derivations often don't give enough detail and there's not much help in the way of example problems, which can make it difficult for the student to use in a classroom setting. Do not expect extremely detailed and thorough treatments of any particular area of surface chemistry. Nearly any chapter in this book could (and does) have entire texts (and courses) devoted exclusively to that one subject. What you can expect from this book is an introduction to the key areas of surface chemistry. The book is loaded with references to point the interested reader in the right direction for more detailed and thorough treatments of the variety of different areas of surface chemistry. For this reason, I have found it to be a good starting point for learning more about several subjects. In short, this book is excellent if you want a broad overview of the field or need a place to start learning about a particular area of surface chemistry. It's not worth much if you are looking for extremely in depth, thorough treatments of specific areas of surface chemistry.

Physical Chemistry of Surfaces.......2001-11-12

I used this book as a text in my class 'Physical Chemistry of Liquids, Interfaces, and Colloids'. This book is not a textbook. My students are complaining all the time about the presentation of topics as well as the extent of derivations, interpretations, and lack of examples. I must admit that I have made a mistake for choosing this text for my course. If you are planing to use it as a text, please go through a few of the derivations and you will notice that the book offers very little to a student.

The new edition is a lot worse than the earlier editions.......1999-05-27

I have found the book very difficult to follow. The book reads more like a research paper than a textbook, in both style and content (for example, there are too many references, most of which are completely unnecesary). Many symbols are left undefined. There are many gaps in the derivations. Many concepts (e.g. the Maragoni effect) are introduced out of proper context. I would not recommend it to anybody. Get an earlier edition if you can.

To many references.......1998-11-17

It was the text book of a discipline in my graduate couse. I and my friends had too many troubles with it, the text is dry with to many references. The text simply order you to look for some reference, instead of explain some obscure part of theory. We only understood many of the problems after Adamson sent the problems answer. The solve some problems we must looked for some references cited in the text, and that took a lot of time. During the couse we used to say that some problems are impossible to solve, others you don't give the correct answer, and the last ones you solve correctely, but you don't understand the why you solve by that way. We used the 5th edition until chapter 10, than we tried another book.

In-Situ Spectroscopy in Heterogeneous Catalysis

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In-Situ Spectroscopy in Heterogeneous Catalysis

Manufacturer: Wiley-VCH
ProductGroup: Book
Binding: Hardcover

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ASIN: 3527302484

Book Description

"Not using in-situ methods to examine catalytic processes is like studying a life with access only to the prenatal and postmortem states." This quote from the world renowned specialist in the field of in situ methods, Gabor A. Somorjai, clearly emphasizes the importance of these techniques in understanding heterogeneous catalysis - a type of chemical reaction used nowadays for most chemically produced supplies and fuels. Yet the fundamental mechanisms are often still not completely understood.
Many of the leading scientists in the field have contributed to this book which provides an overview of the most varied spectroscopic and related methods for studying catalytic structures and their functions during a chemical reaction. While primarily written for users of these methods, this is also a valuable aid to interpreting the phenomena observed. Indispensable for everyone working in the field.

Industrial Catalysis: Optimizing Catalysts and Processes

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Industrial Catalysis: Optimizing Catalysts and Processes
Ruud I. Wijngaarden , K. Roel Westerterp , and A. Kronberg
Manufacturer: Wiley-VCH
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Industrial Catalysis: A Practical Approach

ASIN: 3527285814

Book Description

This is a book for developers of catalysts, and for practitioners working in the field of design, operation, and optimization of chemical reactors in which heterogeneous catalysis is performed. It is designed to give a better understanding of the phenomena which can influence catalyst performance. Since two disciplines, chemistry and chemical engineering, meet in catalyst research and development, this book covers the chemical point of view for engineers, and the engineering point of view for chemists.

It starts with an introduction explaining selectivity, activity and effectiveness providing the fundamentals for the newcomer. Catalyst preparation and catalyst testing are also described.

A method is introduced that can be used to calculate the effectiveness of catalyst pellets as a function of shape, size, pore size, type of kinetics and diffusion, and temperature and pressure conditions. Optimization of catalysts and troubleshooting are also covered. This is a book without any rilvals because of its practical relevance.

Concepts of Modern Catalysis and Kinetics

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Concepts of Modern Catalysis and Kinetics
I. Chorkendorff , and J. W. Niemantsverdriet
Manufacturer: Wiley-VCH
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Binding: Hardcover

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ASIN: 3527305742

Book Description

Until now, the literature has offered a rather limited approach to the use of fundamental kinetics and their application to catalytic reactions. Subsequently, this book spans the full range from fundamentals of kinetics and heterogeneous catalysis via modern experimental and theoretical results of model studies to their equivalent large-scale industrial production processes. The result is key knowledge for students at technical universities and professionals already working in industry.

"...such an enterprise will be of great value to the community, to professionals as well as graduate and undergraduate students attempting to move into the field of modern catalysis and kinetics. I strongly recommend you publish this book based on the proposal."
—Prof. Dr. G. A. Samorjai, University of California

"Both authors are well respected specialists, with a very long record of original top-quality work and an international reputation. A book from these authors will be considered an authoritative piece of work, I definitely support this project and I am looking forward to use the book when published."
—Prof. Dr. D. E. Resasco, University of Oklahoma

Book Description

Catalysis is central to the chemical industry, as it is directly or involved in the production of almost all useful chemical products. In this book the authors, present the definitive account of industrial catalytic processes. Throughout Fundamentals of Industrial Catalytic Processes the information is illustrated with many case studies and problems. This book is valuable to anyone wanting a clear account of industrial catalytic processes, but is particularly useful to industrial and academic chemists and engineers and graduate working on catalysis. This book also:

Covers fundamentals of catalytic processes, including chemistry, catalyst preparation, properties and reaction engineering.
Addresses heterogeneous catalytic processes employed by industry.
Provides detailed data on existing catalysts and catalytic reactions, process design and chemical engineering.
Covers catalysts used in fuel cells.

Customer Reviews:

Excellent Review of Industrial Catalytic Process.......2002-07-17

This book contains a lot of very useful information about a number of industrial catalytic processes. Anybody studying catalytic processes should own this book. It has been a valuable help for my research.

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