Book Description
Following the completion of the Human Genome Project the content and organization of the third edition of Human Molecular Genetics has been thoroughly revised.
*
Part One (Chapters 1-7) covers basic material on DNA structure and function, chromosomes, cells and development, pedigree analysis and the basic techniques used in the laboratory.
*
Part Two (Chapters 8-12) discusses the various genome sequencing projects and the insights they provide into the organization, expression, variation and evolution of our genome.
*
Part Three
(Chapters 13-18) focuses on mapping, identifying and diagnosing the genetic causes of mendelian and complex diseases and cancer.
*
Part Four (Chapters 19-21) looks at the wider horizons of functional genomics, proteomics, bioinformatics, animal models and therapy.
There are new chapters on cells and development and on functional genomics. The sections on complex diseases have been completely rewritten and reorganized, as has the chapter on Genome Projects. Other changes include a new section on molecular phylogenetics (Chapter 12) and the introduction of 'Ethics Boxes' to discuss some of the implications of the new knowledge. Virtually every page has been revised and updated to take account of the stunning developments of the past four years since the publication of the last edition of Human Molecular Genetics.
features:
* Integration of Human Genome Project data throughout the book
* Two new chapters 'Cells and Development' (Chapter 3) and 'Beyond the Genome Project: Functional Genomics, Proteomics and Bioinformatics' (Chapter 19)
* Completely rewritten and reorganized coverage of complex disease genetics
* Increased emphasis on gene function and on applications of genetic knowledge, including ethical issues
* More prominence given to novel approaches to treating disease, such as cell-based therapies, pharmacogenomics, and personalized medicine
* Special topic boxes that include detailed coverage of ethical, legal and social issues, including eugenics, genetic testing and discrimination, germ-line gene therapy and genetic enhancement, and human cloning
* Contains two indices: a general index and one that contains names of diseases and disorders.
Customer Reviews:
clinical geneticist.......2007-03-12
each addition of this text provides a close to current state of the science review of human molecular genetics, it is an excellent way to update onself about the field.
Excellent Reference Text Book for Moelcular Biology.......2007-02-18
I have used this book earlier for my post-doctoral research work and now I am using this book for the online Medical Laboratory Diagnostic course that I am taking. This is an excellent text book for students and researchers. This book not only offers detailed insight into the fundamentals of human molecular genetics but also gives a review of DNA and chromosome structure and function, cellular development, population genetics, cancer genetics, gene therapy, and different techniques of molecular genetic, its applications, and analyses. The figures and illustrations complement the text very well and are easy to understand. I would highly recommend "Human Molecular Genetics" by Tom Strachan and Andrew P. Read to senior-level college students, undergraduate students, graduate students, technologist working in a Molecular Diagnostic Laboratory and researchers.
Good book, nice figures........2007-02-16
I've only read through chapter 8 so far, but the text is understandable and the figures are clear and helpful--especially in the human genome project chapter, which had the potential to be very confusing.
Excellent reference for students and researchers........2007-01-05
This book offers detailed insight into the fundamentals of human molecular genetics. The contents review DNA and chromosome structure and function, cellular development, population genetics, cancer genetics, gene therapy, and a myriad of molecular genetic techniques, applications, and analyses. The figures and illustrations beautifully complement the text with easily understood captions and legends. The organization of the book is such that the reader can easily find a topic of interest without thumbing through the entire text. I would highly recommend "Human Molecular Genetics" by Tom Strachan and Andrew P. Read to senior-level college students, graduate students, and researchers. This is a must-have in the library of any geneticist.
Not the best genetics book out there.......2006-07-01
This book is ok, but you need a decent understanding of genetics to follow many of the chapters. The authors are very effective at overcomplicating very straight forward concepts, which is frustrating if you're simply trying to review, and even worse if you're trying to learn the info for the first time. Definitely NOT for the genetics beginner. I think you can get a better genetics book for the money.
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- viral laboratory diagnosis
|
Laboratory Diagnosis of Viral Infections, Third Edition,
Manufacturer: Informa Healthcare
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Basic Virology
ASIN: 0824719522 |
Book Description
Maintaining the features that made the previous editions so successful, the Third Edition of Laboratory Diagnosis of Viral Infections summarizes the clinical, epidemiological, pathogenetic, and immunological features of a certain disease or infection-providing laboratorians with a practical tool for the principles and techniques used in diagnostic virology. Contains a new chapter covering the important Hantavirus Pulmonary Syndrome! Fully updated since the last edition was published eight years ago and alphabetically arranged for quick and easy reference, Laboratory Diagnosis of Viral Infections, Third Edition now contains: · a complete update on human herpesviruses 6, 7, and 8 · expanded coverage of hepatitis, including enterically transmitted hepatitis viruses and parenterally transmitted viruses · new material on rubella featuring instrumentation for determination of antibodies · a new chapter on the serological diagnosis for selected viruses · a new discussion on HPV and the diagnostic value of molecular detection of the viral DNA · novel developments on rapid test methods for detection of cytomegalovirus · new sections on current information and applications for the amplification and detection of nucleic acids in clinical specimens · a detailed, up-to-date description of Epstein-Barr virus and its effect on immunocompromised patients · and more! Specifically written for laboratory technologists responsible for supplying information to physicians to support or rule out a clinical diagnosis, Laboratory Diagnosis of Viral Infections, Third Edition is a hands-on resource for clinical virologists, clinical microbiologists, clinical pathologists, and graduate and medical school students in these disciplines.
Customer Reviews:
viral laboratory diagnosis.......2003-10-01
i would like to send me any list of books deaking with molecular diagnosis, and detection of microorgnisms.
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Molecular Medicine, Third Edition
R. Trent
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover
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Molecular Diagnostics
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Principles of Molecular Medicine
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Introduction to Molecular Medicine
ASIN: 0126990573 |
Book Description
Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine.
* Extensively revised just after the completion of the Human Genome Project, it provides the latest in molecular medicine developments
* The only book in Molecular Medicine that has undergone 3 editions
* Current practice as well as future developments identified
* Extensive tables, well presented figures - resources for further understanding
Customer Reviews:
Accessible introduction to a complex field.......2006-07-14
This book is advertised as a text for the lay person that can also serve as a textbook for levels ranging from high school to graduate school. Unfortunately, this is a drawback, as the book tries to be all things to all people. The book is written in a conversational style and makes use of numerous cartoon drawings in its explanations. Most of the diagrams are very helpful. However, some drawings are somewhat juvenile and cheesy with faces drawn on enzymes, for example. Extra wide margins contain definitions of words used in the adjacent text as well as occasional jokes and anecdotes. Molecular terms are redefined whenever they are used, so you can skip around in the book with no problem understanding what is being presented.
The introductory chapter compares the molecular biology revolution with the industrial revolution. The next few chapters review bacteria, basic genetics, and the molecular basis of heredity. These are followed by chapters on the basics of DNA replication, transcription, and proteins. All these fundamentals are very well covered, and the diagrams illustrate the points well.
The next few chapters review various techniques including gene transfer in bacteria, with subjects such as transformation and plasmids being well covered. There is also coverage of DNA manipulation including purification, restriction enzymes, and agarose gel electrophoresis. Other chapters concerning methodology cover PCR and DNA sequencing. There is a very good chapter on transgenics that includes micro-injection, knock-outs, and reporter genes. One chapter is devoted specifically to the techniques of molecular biology. This contains a rather brief overview of a wide array of techniques such as bandshift assays, detection systems, FACS, and RFLP that could easily have been expanded. Other chapters focus on the applied side of molecular technology with discussions of topics such as biotechnology products and forensic medicine. The book also brings the subject matter home with very good chapters on inherited diseases as well as cancer and aging, and shows how biology at the molecular level comes into play in each of these matters.
Overall, there is a strong emphasis on DNA at the expense of RNA. Similarly, there is not much information on protein analysis. Even the authors cannot keep up with the speed of the molecular biology revolution, since a number of current popular techniques, such as differential display and quantitative PCR, are only briefly mentioned or are not even included.
Overall, Molecular Biology Made Simple and Fun contains" some useful information, especially with respect to DNA techniques and applications. This book would probably be most applicable as a supplementary textbook for an introductory college class on molecular biology or as a reference guide to look up unfamiliar molecular techniques, such as ones that might be encountered in journal articles. I think it might be too advanced for high school students. I found it a fairly accessible read and very informative, and my background is in engineering and computer science, not biology, other than what I took as a college undergraduate. I highly recommend it.
The table of contents is as folows:
1. Introduction.
2. Bacteria: The Molecular BIologists's Guinea Pigs
3. Basic Genetics
4. Required Reading: The Molecular Basis of Heredity
5. Duplicating the DNA: Replication.
6. Getting the Message Out: Transcription of Genes to Produce Messenger RNA
7. Proteins: The Buck Stops Here
8. Gene Transfer in Bacteria
9. Messing About with DNA
10. Products from BIotechnology
11. Genetic Organization in Higher Organisms
12. Mutations: Things That Go Bump in the Night
13. Inherited Human Disease
14. Cancer and Aging
15. Down on the Farm: Transgenic Plants and Animals
16. Just Do It! Techniques of Molecular BIology
17. PCR: The Polymerase Chain Reaction and Its Many Uses
18. Whodunit? Forensic Medicine and Molecular Biology
19. Gene Creatures, Part I: Viruses, Viroids and Plasmids
20. Gene Creatures, Part II: Jumping Genes and Junk DNA
21. Biological Warfare
22. The Molecular Defense Initiative: Your Immune System at Work
23. Sequencing DNA
24. Molecular Evolution: Memories of "The Way We Were"
25. Classification: BIology for the Neurotic and the Obsessive-Compulsive
26. A Brief History of Molecular Biology
27. Molecular Biology: A Millenial Update
28. What Was Said - What Was Meant: Understanding a Seminar in Molecular Biology.
Great introductory book, but beware of paper quality in 3rd ed.......2006-04-18
As the title says it,it is a great book. The book is so well written. I fist came across this book online and borrowed the second edition from the library. I am an electrochemist and I thoroughly enjoy and understand this book. If you want to learn about molecular biology, where the science is going etc., this is a good book to start with. If you are into investing and would like to understand a bit about what the nerdy scientists are talking about, this book will armor you with that knowledge.
Having said that, I recently bought the third edition and have to say that I am not satisfied with the quality. For $50, we get a book which looks like one of those eastern pirated copies. There are no margins in the book to make notes. The paper quality is so bad that you can see the back page contents while reading and it is annoying. If I were you, I would save money and buy the second edition instead. The second edition has pretty much the same content. I would return this book if Amazon were to refund the entire money!
STRONG BUY .......2005-11-15
Just a witty book to introduce the foundations of molecular biology. Keeps you smiling while you learn. If you have to buy a book of this nature, then this is definitely the one to get. In fact, if I had enough money I'd buy you one, it's that good. You won't be disappointed.
Great Introduction to Molecular Biology.......2005-10-03
I was working with a team of non-scientists that were embarking on a market study focused on customers in the Molecular Biology field. This book (which we referred to as "The Monkey Book") has been a great introduction to provide an overview of the basics of Molecular Biology and common terms/techniques used in the industry.
The book has a lot of humor built in too...which makes its reading very enjoyable.
I would say this is a must-have for those looking to begin learning about Molecular Biology.
Great Review.......2005-06-10
If you are looking to recap and review biology, this is a great book. I graduated with a degree in biology and wish I would have had this book to simplify and guide me through college. For simple explanations that are easy to understand, especially if you forget certain concepts, you should purcahse this book. This is a great book.
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- Soil Microbiology and Biochemistry, Second Edition
- Standard text for soil microbiology
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Soil Microbiology, Ecology and Biochemistry, Third Edition
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Fundamentals of Soil Ecology, Second Edition
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The Biology of Soil: A Community and Ecosystem Approach (Biology of Habitats)
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Principles and Applications of Soil Microbiology
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Environmental Soil Chemistry
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Soil Science Simplified
ASIN: 0125468075 |
Book Description
Now in its third edition, this classic textbook includes basic concepts and applications in agriculture, forestry, environmental science, and a new section entirely devoted to ecology. This revised and updated edition guides students through biochemical and microbial processes in soils and introduces them to microbial processes in water and sediments.
Soil Microbiology, Ecology, and Biochemistry serves as an invaluable resource for students in biogeochemistry, soil microbiology, soil ecology, sustainable agriculture, and environmental amelioration.
NEW TO THIS EDITION:
* New section on Ecology integrated with biochemistry and microbiology
* Sections on exciting new methodology such as tracers, molecular analysis and computers that will allow great advances in this field
* Six new chapters: bioremediation, soil molecular biology, biodiversity, global climate change, basic physiology and ecological interpretations
* Expanded with contributions from leading soil microbiologists and agronomists on both fundamental and applied aspects of the science
* Full-color figures
* Includes a website with figures for classroom presentation use
Customer Reviews:
Soil Microbiology and Biochemistry, Second Edition.......2006-02-25
Book in very good condition when arrived, was new when purchased. Cost was a little high at 62.00 dollars. Received in a timely manner.
Standard text for soil microbiology.......2002-09-18
I was a graduate student in soils and forestry when I took a class in soil microbiology that used this text. It is essentially the gold standard for soil micro texts. It isn't overly technical, but it includes a thorough analysis of the basic concepts needed to understand most aspects of soil microbiology research and application. The book uses mostly agronomic examples, but there is enough variety of ecosystems to make it useful for those working in forestry, grasslands, and almost any type of soil. Those interested in detailed discussions of molecular microbial methods or biotechnology may be disappointed, but for the general student looking to understand what those billion microbes per teaspoon of soil are doing, this book is the best introduction out there.
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Laboratory Methods in Food Microbiology, Third Edition
Wilkie F. Harrigan
Manufacturer: Academic Press
ProductGroup: Book
Binding: Paperback
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Food Microbiology Laboratory (Crc Series in Contemporary Food Science)
ASIN: 0123260434 |
Book Description
Laboratory Methods in Food Microbiology describes a wide range of methods for use in the microbiological analysis of foods, including approaches to counting and detection procedures for microorganisms, identification of bacteria, yeasts and fungi, microbiological analysis for the main food commodity groups, and safety in the food microbiology laboratory. The book also discusses specific food poisoning outbreaks in the United States.
CONTENTS INCLUDE:
* Comprehensive methods and advice on choosing appropriate techniques
* Discussion of internationally recognized standards
* Detection and enumeration of food-borne pathogenic and toxigenic microorganisms
* Detailed sections on analyses appropriate for the main food commodity groups
* Identification of bacteria, yeasts, and fungi isolated from foods
* Safety in the food microbiology laboratory
* Appendix of recipes for media and reagents
Book Description
Just as the previous editions of this highly regarded text responded to the transitions of their time, the third edition reflects the current evolution of food microbiology and explores the most recent developments in the discipline. Completely revised and updated, Fundamental Food Microbiology, Third Edition includes the latest information on microbial stress response, food biopreservatives, recent pathogens of importance (such as Helicobacter pylori and BSE), and control by novel processing technologies. A new chapter addresses foodborne disease concerns in ready-to-eat foods, and an expanded chapter on microbial stress investigates the importance of stress response in foods. The book features updated coverage of spoilage bacteria in refrigerated foods, presents new sections on fresh-cut fruits and vegetables, and includes questions and selected readings at the end of each chapter. Providing comprehensive information on the interactions of microorganisms and food, this timely resource enhances understanding of food microbiology in a logical and concise manner. It will be a valuable reference for professionals and students involved in food and microbiology.
Book Description
Numerous infectious diseases are described as idiopathic, meaning that "the cause is a complete mystery." For many idiopathic diseases, the causes become clear when certain techniques are applied to the patient's blood or other tissues. Cell Wall Deficient Forms: Stealth Pathogens, Third Edition describes these techniques. In the case of tuberculosis, a disease that has recently regained importance because the strains have acquired antibiotic resistance, the book describes a method that is widely used abroad. This method typically renders the diagnosis within 72 hours. The book examines a plethora of issues and provides answers to the following questions: o What organism should be added to the childhood vaccine, especially for boys? o What bacteria in its pleomorphic state is found in direct smears of synovial fluid of rheumatoid arthritis cases? o In which chronic diseases ( presently considered as being of unknown origin) is an acid-fast organism routinely found in smears of 72 hour blood cultures? o Which "bacterium" has a life cycle in the human erythrocyte as complex as that of Plasmodium malaria? o Which common pathogen's L Form can permanently damage myocardium mammaliam? Cell Wall Deficient Forms: Stealth Pathogens, Third Edition discloses significant aspects of microbiology, aspects that are not taught, and which go unrecognized in the clinical laboratory.
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Mucosal Immunology, Two-Volume Set, Third Edition
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover
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Immunobiology
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Cellular and Molecular Immunology
ASIN: 0124915434 |
Book Description
Mucosal immunology is so important since most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes.
Mucosal Immunology, now two volumes and in its third edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective and excellent organization.
* The most comprehensive text on mucosal immunology from internationally recognized experts in the field
* Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases
* Contains nine new chapters and an expanded appendix
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- Life After Life: The Investigation of a Phenomenon--Survival of Bodily Death
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